Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Jessica Sher"'
Autor:
Juan Yan, Yuedan Chen, Amish J. Patel, Sarah Warda, Cindy J. Lee, Briana G. Nixon, Elissa W.P. Wong, Miguel A. Miranda-Román, Ning Yang, Yi Wang, Mohini R. Pachai, Jessica Sher, Emily Giff, Fanying Tang, Ekta Khurana, Sam Singer, Yang Liu, Phillip M. Galbo Jr., Jesper L.V. Maag, Richard P. Koche, Deyou Zheng, Cristina R. Antonescu, Liang Deng, Ming O. Li, Yu Chen, Ping Chi
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 17 (2022)
Immune checkpoint blockade (ICB) has demonstrated clinical success in “inflamed” tumors with substantial T cell infiltrates, but tumors with an immune-desert tumor microenvironment (TME) fail to benefit. The tumor cell–intrinsic molecular mecha
Externí odkaz:
https://doaj.org/article/5f861c04fcd24ec597718aa39450c410
Autor:
Dan Li, Yu Zhan, Naitao Wang, Fanying Tang, Cindy J. Lee, Gabriella Bayshtok, Amanda R. Moore, Elissa W. P. Wong, Mohini R. Pachai, Yuanyuan Xie, Jessica Sher, Jimmy L. Zhao, Makhzuna Khudoynazarova, Anuradha Gopalan, Joseph Chan, Ekta Khurana, Peter Shepherd, Nora M. Navone, Ping Chi, Yu Chen
Publikováno v:
Science Advances. 9
The mechanisms underlying ETS -driven prostate cancer initiation and progression remain poorly understood due to a lack of model systems that recapitulate this phenotype. We generated a genetically engineered mouse with prostate-specific expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86854dc7e7acec98f3d100273e4ef8c8
https://doi.org/10.1126/sciadv.adc9446
https://doi.org/10.1126/sciadv.adc9446
Autor:
Ping Chi, Yu Chen, Cristina R. Antonescu, Richard P. Koche, Deyou Zheng, Yuanyuan Xie, Alan Chramiec, Katie Yang Li, Shipra Shukla, Youxin Guan, Shangqian Wang, Zhen Cao, Inna Sirota, Kemal Deniz, Dan Li, Jenny Q. Zhang, Devan Murphy, Elissa W.P. Wong, Jessica Sher, Yuedan Chen, Leili Ran
Figure S1. Expression of forkhead family transcription factors in GIST; S2. Motif analysis of the FOXF1 cistrome and validation of FOXF1 binding sites in GIST 48 cells; S3. FOXF1 regulates ETV1, KIT, and ETV1- and KIT-dependent transcriptome as well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc08cd7300f2658298ce2882eeed127
https://doi.org/10.1158/2159-8290.22532126.v1
https://doi.org/10.1158/2159-8290.22532126.v1
Autor:
Ping Chi, Yu Chen, Cristina R. Antonescu, Richard P. Koche, Deyou Zheng, Yuanyuan Xie, Alan Chramiec, Katie Yang Li, Shipra Shukla, Youxin Guan, Shangqian Wang, Zhen Cao, Inna Sirota, Kemal Deniz, Dan Li, Jenny Q. Zhang, Devan Murphy, Elissa W.P. Wong, Jessica Sher, Yuedan Chen, Leili Ran
S1. De novo motifs in GIST-Specific ETV1 enhancers; S2. De novo motifs in Prostate Specific ETV1 enhancers; S3. De novo motifs in Shared ETV1 enhancers; S4. De novo motifs in Shared ETV1 promoters; S5: Expression of Forkhead Transcription Factors in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a9dd2b1a8646d955f5eaeb2060bc78
https://doi.org/10.1158/2159-8290.22532123
https://doi.org/10.1158/2159-8290.22532123
Autor:
Ping Chi, Yu Chen, Cristina R. Antonescu, Yu Zhan, Shipra Shukla, Yuanyuan Xie, Youxin Guan, Edward Walczak, Shangqian Wang, Zhen Cao, Jessica Sher, Devan Murphy, Leili Ran
Combination of homozygous BrafV600E activation and Trp53 loss induced dramatic ICC hyperplasia in stomach, cecum and large intestine, but not in small intestine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::962302b697923be0ddd4edc24434d8e9
https://doi.org/10.1158/0008-5472.22414659
https://doi.org/10.1158/0008-5472.22414659
Autor:
Ping Chi, Yu Chen, Cristina R. Antonescu, Yu Zhan, Shipra Shukla, Yuanyuan Xie, Youxin Guan, Edward Walczak, Shangqian Wang, Zhen Cao, Jessica Sher, Devan Murphy, Leili Ran
Gastrointestinal stromal tumor (GIST) is the most common subtype of sarcoma. Despite clinical advances in the treatment of KIT/PDGFRA–mutant GIST, similar progress against KIT/PDGFRA wild-type GIST, including mutant BRAF-driven tumors, has been lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11a7e5ca44f5894be551497f0aa5d915
https://doi.org/10.1158/0008-5472.c.6509046.v1
https://doi.org/10.1158/0008-5472.c.6509046.v1
Autor:
Laura Nixon, Laura Sheard, Jessica Sheringham, Amy Creaser, Halima Iqbal, Patience Gansallo, Liina Mansukoski, Maria Bryant, Bridget Lockyer
Publikováno v:
Health Research Policy and Systems, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Addressing the upstream social determinants of health (e.g. built environment, education) can reduce the burden of non-communicable diseases. To do so effectively often requires system-wide collaboration. However, collaborating ac
Externí odkaz:
https://doaj.org/article/c60b9f6a2d4749fcab3d17efd26021d7
Autor:
Tommer Spence, Alison Howarth, David Reid, Jessica Sheringham, Vanessa Apea, David Crundwell, Sara Day, Claire Dewsnap, Louise Jackson, Catherine H. Mercer, Hamish Mohammed, Jonathan D. C. Ross, Ann Sullivan, Andy Williams, Andrew Winter, Geoff Wong, Fiona Burns, Jo Gibbs
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Sexually transmitted infections (STIs) are a serious public health issue in many countries. Online postal self-sampling (OPSS) is increasingly used to test for STIs, a trend accelerated by the COVID-19 pandemic. There remains limi
Externí odkaz:
https://doaj.org/article/8e0b8691874e4612b204726d9de1ccbd
Autor:
Juan Yan, Yuedan Chen, Amish J. Patel, Sarah Warda, Briana G. Nixon, Elissa W.P. Wong, Miguel A. Miranda-Román, Cindy J. Lee, Ning Yang, Yi Wang, Jessica Sher, Emily Giff, Fanying Tang, Ekta Khurana, Sam Singer, Yang Liu, Phillip M. Galbo, Jesper L. Maag, Richard P. Koche, Deyou Zheng, Liang Deng, Cristina R. Antonescu, Ming Li, Yu Chen, Ping Chi
Immune checkpoint blockade (ICB) has demonstrated clinical success in “inflamed” tumors with significant T-cell infiltrates, but tumors with an immune-desert tumor microenvironment (TME) fail to benefit. The tumor cell-intrinsic molecular mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c3e30d42629a5df69dc99352a3c9ef0
https://doi.org/10.1101/2022.05.27.493507
https://doi.org/10.1101/2022.05.27.493507
Autor:
Juan Yan, Yuedan Chen, Amish J. Patel, Sarah Warda, Cindy J. Lee, Briana G. Nixon, Elissa W.P. Wong, Miguel A. Miranda-Román, Ning Yang, Yi Wang, Mohini R. Pachai, Jessica Sher, Emily Giff, Fanying Tang, Ekta Khurana, Sam Singer, Yang Liu, Phillip M. Galbo, Jesper L.V. Maag, Richard P. Koche, Deyou Zheng, Cristina R. Antonescu, Liang Deng, Ming O. Li, Yu Chen, Ping Chi
Publikováno v:
The Journal of clinical investigation. 132(17)
Immune checkpoint blockade (ICB) has demonstrated clinical success in "inflamed" tumors with substantial T cell infiltrates, but tumors with an immune-desert tumor microenvironment (TME) fail to benefit. The tumor cell-intrinsic molecular mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c931fb44c66ea5c53605e85e8a92e709
https://pubmed.ncbi.nlm.nih.gov/35852856
https://pubmed.ncbi.nlm.nih.gov/35852856