Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jessica Saltarski"'
Autor:
Kemp H. Kernstine, Ralph J. DeBerardinis, Chyndhri Padmanabhan, Jessica Saltarski, Quyen N. Do, Ivan Pedrosa, Lorraine Pelosof, Chul Ahn, Rachael Skelton, David E. Gerber, Raja Reddy Kallem, Sahba Kasiri, Scott I. Reznik, Yin Xi, Farjana J. Fattah, Rolf A. Brekken, Richard D. Leff, Vaidehi Chembukar, William C. Putnam, James Kim, Robert E. Lenkinski, Brandon Faubert, Qing Yuan, Indhumathy Subramaniyan
Publikováno v:
Clin Cancer Res
Purpose: Itraconazole has been repurposed as an anticancer therapeutic agent for multiple malignancies. In preclinical models, itraconazole has antiangiogenic properties and inhibits Hedgehog pathway activity. We performed a window-of-opportunity tri
Autor:
Jason Y. Park, Yvonne Gloria-McCutchen, Rong Lu, David E. Gerber, Saad A. Khan, Jessica Saltarski, Edward K. Wakeland, Quan Zhen Li, Bonnie L. Bermas, Farjana J. Fattah, Mitchell S. von Itzstein, Shaheen Khan, Yang Xie, David R. Karp
Publikováno v:
The Oncologist
Immune checkpoint inhibitor (ICI)‐induced immune‐related adverse events (irAEs) may affect almost any organ system and occur at any point during therapy. Autoantibody analysis may provide insight into the mechanism, nature, and timing of these ev
Autor:
Shaheen Khan, Bonnie L. Bermas, Edward K. Wakeland, Rong Lu, Jason Y. Park, Yang Xie, Murtaza Ahmed, Jessica Saltarski, Saad A. Khan, Farjana J. Fattah, Vinita Popat, Quan Zhen Li, David R. Karp, David E. Gerber, Yvonne Gloria-McCutchen, Mitchell S. von Itzstein
Publikováno v:
Oncologist
Immune-related adverse events induced by immune checkpoint inhibitor (ICI) therapy may affect diverse organ systems, including skeletal and cardiac muscle. ICI-associated myositis may result in substantial morbidity and occasional mortality. We prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc85a6ff120f2f47167eaf3ecd045a33
https://europepmc.org/articles/PMC7418340/
https://europepmc.org/articles/PMC7418340/
Publikováno v:
Clinical Lung Cancer. 18:626-630
Increasingly, analysis of tumor tissue samples for predictive and pharmacodynamic biomarkers is incorporated into lung cancer clinical trials. We determined the time and effort required for tissue acquisition and submission.We analyzed data from pati
Autor:
Mitchell S. von Itzstein, David Hsiehchen, David E. Gerber, Nazima Sultana, Murtaza Ahmed, Shaheen Khan, Jared Ostmeyer, Thomas Sheffield, Jason Y. Park, Vinita Popat, Farjana J. Fattah, Edward K. Wakeland, Saad A. Khan, Yvonne Gloria-McCutchen, Quan Zhen Li, Jessica Saltarski, Yang Xie
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundIncreased body mass index (BMI) has been associated with improved response to immune checkpoint inhibitors (ICIs) in multiple cancer types. We evaluated associations between BMI, ICI dosing strategy, and clinical outcomes.MethodsWe abstract
Autor:
Shaheen Khan, Benjamin Aaron Bleiberg, Donglu Xie, Murtaza Ahmed, Mary Katherine Watters, Jason Y. Park, Jessica Saltarski, Saad A. Khan, Farjana J. Fattah, Edward K. Wakeland, Vinita Popat, David Hsieh, Rong Lu, David E. Gerber, Yvonne Gloria-McCutchen, Mitchell S. von Itzstein
Publikováno v:
Journal of Clinical Oncology. 38:3043-3043
3043 Background: Baseline circulating white blood cell differential counts have been proposed as possible markers of response to Immune therapy (ICI) and immune toxicity (irAE), but have not been validated for clinical practice. Methods: 214 patients
Autor:
Noah Sorrelle, Samantha Mannala, Hak Choy, Rolf A. Brekken, Puneeth Iyengar, Jessica Saltarski, Kenneth D. Westover, Jonathan E. Dowell, Sawsan Rashdan, Hong Zhu, Robert Timmerman, David E. Gerber, Kasia Harrah, Randall S. Hughes, Saad A. Khan, Laurin L. Priddy
Publikováno v:
Web of Science
e21571 Background: ALK -targeting drugs and SABR are combined in patients with metastatic cancer, anecdotally yielding clinical benefit. However, the precise impact of the combination and the optimal time to introduce SABR remain unknown. Methods: Th
Autor:
Jessica Saltarski, Farjana J. Fattah, Murtaza Ahmed, Noah Sorrelle, Yvonne Gloria-McCutchen, Saad A. Khan, Shaheen Khan, David Hsieh, David E. Gerber, Jason Y. Park, Rong Lu, Rolf A. Brekken, Mitchell S. von Itzstein, Donglu Xie, Vinita Popat, Benjamin Aaron Bleiberg, Yuqing Zhang, Mary Katherine Watters
Publikováno v:
Journal of Clinical Oncology. 38:e15126-e15126
e15126 Background: The mechanisms by which immune checkpoint inhibitors (ICI) cause immune related adverse events (irAE) are not clear. No current blood tests predict which patients will suffer irAEs. Methods: 70 cancer patients had blood drawn prior
Autor:
Jessica Saltarski, Xin Luo, Shaheen Khan, Saad A. Khan, Farjana J. Fattah, Rong Lu, Edward K. Wakeland, Quan Li, Yvonne Gloria-McCutchen, Yang Xie, David E. Gerber
Publikováno v:
British Journal of Cancer
Background Up to 40% of cancer patients on immune checkpoint inhibitors develop clinically significant immune-related adverse events (irAEs). The role of host immune status and function in predisposing patients to the development of irAEs remains unk
Intracellular compartmentalization and trafficking of molecules plays a critical role in complex and essential cellular processes. In lung cancer and other malignancies, aberrant nucleocytoplasmic transport of tumor suppressor proteins and cell cycle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ed2fd5c74b6e1215644521d0f2c83c
https://europepmc.org/articles/PMC5572747/
https://europepmc.org/articles/PMC5572747/