Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Jessica Sabourin"'
Autor:
Hélène Le Ribeuz, Bastien Masson, Mary Dutheil, Angèle Boët, Antoine Beauvais, Jessica Sabourin, Vincent Thomas De Montpreville, Véronique Capuano, Olaf Mercier, Marc Humbert, David Montani, Fabrice Antigny
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2023)
AimsWe hypothesized that the ATP-sensitive K+ channels (KATP) regulatory subunit (ABCC9) contributes to PAH pathogenesis. ABCC9 gene encodes for two regulatory subunits of KATP channels: the SUR2A and SUR2B proteins. In the KATP channel, the SUR2 sub
Externí odkaz:
https://doaj.org/article/99c8714ef1d44eb39bf6aad8c7b0d47e
Autor:
Jessica Sabourin, Antoine Beauvais, Rui Luo, David Montani, Jean-Pierre Benitah, Bastien Masson, Fabrice Antigny
Publikováno v:
Cells, Vol 11, Iss 20, p 3282 (2022)
Right ventricular failure (RVF) is the most important prognostic factor for morbidity and mortality in pulmonary arterial hypertension (PAH) or pulmonary hypertension (PH) caused by left heart diseases. However, right ventricle (RV) remodeling is und
Externí odkaz:
https://doaj.org/article/e899352baef14debaa355a79f7dcd4c7
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The archetypal store-operated Ca2+ channels (SOCs), Orai1, which are stimulated by the endo/sarcoplasmic reticulum (ER/SR) Ca2+ sensor stromal interaction molecule 1 (STIM1) upon Ca2+ store depletion is traditionally viewed as instrumental for the fu
Externí odkaz:
https://doaj.org/article/6bcbdac852c94f8ca2b463b5afb2796d
Autor:
Fiona Bartoli, Soraya Moradi Bachiller, Fabrice Antigny, Kaveen Bedouet, Pascale Gerbaud, Jessica Sabourin, Jean-Pierre Benitah
Publikováno v:
Cells, Vol 9, Iss 1, p 47 (2019)
Whereas cardiac TRPC (transient receptor potential canonical) channels and the associated store-operated Ca2+ entry (SOCE) are abnormally elevated during cardiac hypertrophy and heart failure, the mechanism of this upregulation is not fully elucidate
Externí odkaz:
https://doaj.org/article/c447f6aca1034dadbefc4bc835966cdc
Autor:
Mélanie Lambert, Véronique Capuano, Andrea Olschewski, Jessica Sabourin, Chandran Nagaraj, Barbara Girerd, Jason Weatherald, Marc Humbert, Fabrice Antigny
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 3162 (2018)
Pulmonary arterial hypertension (PAH) is a multifactorial and severe disease without curative therapies. PAH pathobiology involves altered pulmonary arterial tone, endothelial dysfunction, distal pulmonary vessel remodeling, and inflammation, which c
Externí odkaz:
https://doaj.org/article/f9cf6bd3f4284f64907bcd071ccc1b04
Autor:
Rui Luo, Masson Bastien, Guillaume Fadel, Ali Akamkam, Romain Perrier, Simon Dang Van, Dorothée Brunet, Florence Lefebvre, Angele Boet, David Montani, Marc Humbert, Ana Maria Gomez Garcia, Jean-Pierre Benitah, Julien Guihaire, Olaf Mercier, Jessica Sabourin, Fabrice Antigny
Publikováno v:
Archives of Cardiovascular Diseases Supplements. 15:203-204
Autor:
Bastien Masson, Hélène Le Ribeuz, Jessica Sabourin, Loann Laubry, Emily Woodhouse, Richard Foster, Yann Ruchon, Mary Dutheil, Angèle Boët, Maria-Rosa Ghigna, Vincent Thomas De Montpreville, Olaf Mercier, David J. Beech, Jean-Pierre Benitah, Marc A. Bailey, Marc Humbert, David Montani, Véronique Capuano, Fabrice Antigny
Publikováno v:
Circulation research. 131(9)
Background: Pulmonary arterial hypertension (PAH) is characterized by progressive distal pulmonary artery (PA) obstruction, leading to right ventricular hypertrophy and failure. Exacerbated intracellular calcium (Ca 2+ ) signaling contributes to abno
Autor:
Catherine Rucker-Martin, Justin F. X. Ainscough, Baptiste Rode, Philippe Mateo, Florence Lefebvre, Jessica Sabourin, Hollie L. Appleby, Richard Foster, Kaveen Bedouet, Susana Gomez, Jian Shi, Alexander-Francisco Bruns, Fabrice Antigny, Jean-Pierre Benitah, Marc A. Bailey, Rajendra Gosain, Heba Shawer, Fiona Bartoli, Pascale Gerbaud, Richard S. Young, Marjolaine Debant, Jeffrey Plante, A.M. Gomez, Mark T. Kearney, Katherine Norman, David J. Beech
Publikováno v:
Circulation
Supplemental Digital Content is available in the text.
Background: Orai1 is a critical ion channel subunit, best recognized as a mediator of store-operated Ca2+ entry (SOCE) in nonexcitable cells. SOCE has recently emerged as a key contributor o
Background: Orai1 is a critical ion channel subunit, best recognized as a mediator of store-operated Ca2+ entry (SOCE) in nonexcitable cells. SOCE has recently emerged as a key contributor o
Autor:
Marc Humbert, Olaf Mercier, Fabrice Antigny, Emily Woodhouse, Mary Dutheil, Jean-Pierre Benitah, Maria-Rosa Ghigna, Hélène Le Ribeuz, Yann Ruchon, Véronique Capuano, Bastien Masson, Angèle Boet, Richard Foster, Marc A. Bailey, David Montani, Jessica Sabourin, David J. Beech
Publikováno v:
Pulmonary hypertension.
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The archetypal store-operated Ca2+ channels (SOCs), Orai1, which are stimulated by the endo/sarcoplasmic reticulum (ER/SR) Ca2+ sensor stromal interaction molecule 1 (STIM1) upon Ca2+ store depletion is traditionally viewed as instrumental for the fu