Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Jessica Saben"'
Autor:
Chad N. Brocker, Thomas Velenosi, Hania K. Flaten, Glenn McWilliams, Kyle McDaniel, Shelby K. Shelton, Jessica Saben, Kristopher W. Krausz, Frank J. Gonzalez, Andrew A. Monte
Publikováno v:
Human Genomics, Vol 14, Iss 1, Pp 1-9 (2020)
Abstract Introduction Metoprolol succinate is a long-acting beta-blocker prescribed for the management of hypertension (HTN) and other cardiovascular diseases. Metabolomics, the study of end-stage metabolites of upstream biologic processes, yield ins
Externí odkaz:
https://doaj.org/article/3aa5f026348a45d1a54d74ed99cf37ff
Autor:
Hunter B. Moore, Jessica Saben, Ivan Rodriguez, Yanik J. Bababekov, James J. Pomposelli, Dor Yoeli, Tanner Ferrell, Megan A. Adams, Thomas J. Pshak, Bruce Kaplan, Elizabeth A. Pomfret, Trevor L. Nydam
Publikováno v:
Liver Transplantation.
Publikováno v:
Curr Dev Nutr
OBJECTIVES: Branched chain amino acids (AA) (BCAAs: leucine (Leu), isoleucine (Ile), and valine) and aromatic AA (AAAs: phenylalanine (Phe) and tyrosine (Tyr)) have been hypothesized to take part in early-life metabolic programing. To date studies te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce30aac54435467202151a2af127a2f
https://europepmc.org/articles/PMC8182077/
https://europepmc.org/articles/PMC8182077/
Autor:
Hania K. Flaten, John Schwartz, Shelby K. Shelton, Brandon Sonn, Karen Ryall, Jessica Saben, Andrew A. Monte
Publikováno v:
International Journal of Clinical Pharmacology and Therapeutics
Objective To identify single nucleotide variants (SNVs) associated with lisinopril effectiveness. Materials and methods This was an observational study using a candidate gene approach to examine SNVs associated with lisinopril effectiveness. Drug eff
Publikováno v:
Nutrients, Vol 13, Iss 446, p 446 (2021)
Nutrients
Volume 13
Issue 2
Nutrients
Volume 13
Issue 2
Human milk oligosaccharides (HMOs) are bioactive molecules playing a critical role in infant health. We aimed to quantify the composition of HMOs of women with normal weight (18.5&ndash
24.9 kg/m2), overweight (25.0&ndash
29.9 kg/m2), or ob
24.9 kg/m2), overweight (25.0&ndash
29.9 kg/m2), or ob
Publikováno v:
Nutrients, Vol 12, Iss 2209, p 2209 (2020)
Nutrients
Volume 12
Issue 8
Nutrients
Volume 12
Issue 8
Human milk oligosaccharides (HMOs) are bioactive molecules in human milk that play a critical role in infant health. Obesity and associated metabolic aberrations can negatively impact lactation and alter milk composition. Here, the relationship betwe
Publikováno v:
The American journal of clinical nutrition. 112(5)
Background Human milk composition is altered by maternal obesity. The association between milk metabolites and infant outcomes has not been thoroughly investigated. Objectives This study aimed to quantify maternal adiposity-related differences in the
Publikováno v:
Journal of the Endocrine Society
Bone mass and quality in humans are controlled by numerous genetic and environmental factors that are not fully understood. Increasing evidence has indicated that maternal metabolic dysregulation impairs multiple physiological processes in the adult
Autor:
Shelby K. Shelton, Diana Abbott, Kayla Williamson, Jessica Saben, Andrew A. Monte, Peter L. Anderson, Hania K. Flaten, Lane R. Bushman, Farah Abdelmawla, Kelsey West, Kyle McDaniel
Publikováno v:
Clinical Pharmacology & Therapeutics. 104:933-939
Drug-drug interactions have been demonstrated to alter cytochrome 2D6 (CYP2D6) enzyme phenotype due to inhibitor ingestion, although it is unclear how substrate interactions affect phenotype. This was a pragmatic clinical trial examining the kinetics
Publikováno v:
Physiology. 32:51-59
Recent human and animal studies investigating the roles of the genome, epigenome, and environmental cues have identified associations between offspring predisposition to life-long obesity/metabolic disease and epigenetic modifications such as DNA met