Výsledky vyhledávání - "Jessica S. Nikitczuk"

N-cadherin regulates molecular organization of excitatory and inhibitory synaptic circuits in adult hippocampus in vivo

Autor: Matthew L. Shapiro, Shekhar B. Patil, Deanna L. Benson, Jessica S. Nikitczuk, George W. Huntley, Joseph R. Scarpa, Bridget A. Matikainen-Ankney

Publikováno v: Hippocampus. 24:943-962

N-Cadherin and β-catenin form a transsynaptic adhesion complex required for spine and synapse development. In adulthood, N-cadherin mediates persistent synaptic plasticity, but whether the role of N-cadherin at mature synapses is similar to that at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe782f60b250f5789fec2ad572c729e0
https://doi.org/10.1002/hipo.22282

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Persistence of Coordinated Long-Term Potentiation and Dendritic Spine Enlargement at Mature Hippocampal CA1 Synapses Requires N-Cadherin

Autor: Ozlem Bozdagi, Tonya R. Anderson, Erik B. Bloss, Jessica S. Nikitczuk, Deanna L. Benson, George W. Huntley, Qiang Zhou, Xiao-bin Wang, Glenn L. Radice

Publikováno v: The Journal of Neuroscience. 30:9984-9989

Persistent changes in spine shape are coupled to long-lasting synaptic plasticity in hippocampus. The molecules that coordinate such persistent structural and functional plasticity are unknown. Here, we generated mice in which the cell adhesion molec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::05039d235a91edaed38e02c48c022d31
https://doi.org/10.1523/jneurosci.1223-10.2010

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Nanoscale Anionic Macromolecules Can Inhibit Cellular Uptake of Differentially Oxidized LDL

Autor: Jessica S. Nikitczuk, Kathryn E. Uhrich, Prabhas V. Moghe, Evangelia Chnari

Publikováno v: Biomacromolecules. 7:597-603

Nanoscale particles could be synthetically designed to potentially intervene in lipoprotein matrix retention and lipoprotein uptake in cells, processes central to atherosclerosis. We recently reported on lipoprotein interactions of nanoscale micelles

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b7115ea0e066dfccbfdd279b20c537
https://doi.org/10.1021/bm0506905

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Extracellular proteolysis by matrix metalloproteinase-9 drives dendritic spine enlargement and long-term potentiation coordinately

Autor: Qiang Zhou, Xiao-bin Wang, Zu Wei Zhai, Ozlem Bozdagi, Jessica S. Nikitczuk, George W. Huntley

Persistent dendritic spine enlargement is associated with stable long-term potentiation (LTP), and the latter is thought to underlie long-lasting memories. Extracellular proteolytic remodeling of the synaptic microenvironment could be important for s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c27c9993a012368b8f4cf1b981afb10
https://europepmc.org/articles/PMC2614793/

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Engineered polymeric nanoparticles for receptor-targeted blockage of oxidized low density lipoprotein uptake and atherogenesis in macrophages

Autor: Prabhas V. Moghe, Kathryn E. Uhrich, Evangelia Chnari, Jinzhong Wang, Jessica S. Nikitczuk

Publikováno v: Biomacromolecules. 7(6)

Strategies to prevent the uptake of modified low density lipoproteins (LDLs) by immune cells, a major trigger of inflammation and atherogenesis, are challenged by complex interfacial factors governing LDL receptor-mediated uptake. We examine a new ap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05cd223f13b0e76b445c18a4d77d026f
https://pubmed.ncbi.nlm.nih.gov/16768400

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