Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jessica S. Elman"'
Autor:
Jessica S. Elman, Thomas K. Ni, Kristen E. Mengwasser, Dexter Jin, Ania Wronski, Stephen J. Elledge, Charlotte Kuperwasser
Publikováno v:
Cell Reports, Vol 28, Iss 13, Pp 3435-3449.e5 (2019)
Summary: Comprehensive sequencing approaches have allowed for the identification of the most frequent contributors to cancer, known as drivers. They have also revealed a class of mutations in understudied, infrequently altered genes, referred to as
Externí odkaz:
https://doaj.org/article/e617fd7258c847d486aa6bcbaa90f6f9
Role for Egr1 in the Transcriptional Program Associated with Neuronal Differentiation of PC12 Cells.
Autor:
Kenneth W Adams, Sergey Kletsov, Ryan J Lamm, Jessica S Elman, Steven Mullenbrock, Geoffrey M Cooper
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170076 (2017)
PC12 cells are a well-established model to study how differences in signal transduction duration can elicit distinct cell behaviors. Epidermal growth factor (EGF) activates transient ERK signaling in PC12 cells that lasts 30-60 min, which in turn pro
Externí odkaz:
https://doaj.org/article/4694657aa41d476897bb4514f675c79f
Autor:
Jessica S Elman, Ryan C Murray, Fangjing Wang, Keyue Shen, Shan Gao, Kevin E Conway, Martin L Yarmush, Bakhos A Tannous, Ralph Weissleder, Biju Parekkadan
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89882 (2014)
Transient cell therapy is an emerging drug class that requires new approaches for pharmacological monitoring during use. Human mesenchymal stem cells (MSCs) are a clinically-tested transient cell therapeutic that naturally secrete anti-inflammatory f
Externí odkaz:
https://doaj.org/article/bebf5db53a4d4a56accd59d2bbe8606b
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Nature
Nature
In cancer, tumor suppressor genes (TSGs) are frequently truncated, causing their encoded products to be non-functional or dominant-negative. We previously showed that premature polyadenylation (pPA) of MAGI3 truncates the gene, switching its function
Publikováno v:
Scientific Reports
In cancer, tumor suppressor genes (TSGs) are frequently truncated, causing their encoded products to be non-functional or dominant-negative. We previously showed that premature polyadenylation (pPA) of MAGI3 truncates the gene, switching its function
Autor:
Keyue Shen, Michael J. Cima, Jungwoo Lee, Arjun K. Manrai, Biju Parekkadan, Martin L. Yarmush, Aaron Gabow, Joshua Yarmush, Yunxin Jiao, Jack M. Milwid, Jessica S Elman, Anne L. Fletcher, Matthew D. Li
Publikováno v:
Elsevier
The secreted proteins from a cell constitute a natural biologic library that can offer significant insight into human health and disease. Discovering new secreted proteins from cells is bounded by the limitations of traditional separation and detecti
Autor:
Stephen J. Elledge, Charlotte Kuperwasser, Ania Wronski, Dexter X. Jin, Jessica S Elman, Kristen E. Mengwasser, Thomas K. Ni
Publikováno v:
Cell reports
Cell Reports, Vol 28, Iss 13, Pp 3435-3449.e5 (2019)
Cell Reports, Vol 28, Iss 13, Pp 3435-3449.e5 (2019)
SUMMARY Comprehensive sequencing approaches have allowed for the identification of the most frequent contributors to cancer, known as drivers. They have also revealed a class of mutations in understudied, infrequently altered genes, referred to as
Publikováno v:
Scientific Reports
Cancer-associated fibroblasts (CAFs) are a major cancer-promoting component in the tumor microenvironment (TME). The dynamic role of human CAFs in cancer progression has been ill-defined because human CAFs lack a unique marker needed for a cell-speci
Autor:
Shannon J. Turley, Janice M Nieves, Ryan Murray, Biju Parekkadan, Flavian D. Brown, Konstantin Knoblich, J. D'Rozario, Nima Saeidi, Anne L. Fletcher, Frank A. Schildberg, Jessica S Elman, Jillian L. Astarita, Tracy Sp Heng, Richard L. Boyd
Publikováno v:
Science Translational Medicine. 6
Sepsis is an aggressive inflammatory syndrome and a global health burden estimated to kill 7.3 million people annually. Single-target molecular therapies have not addressed the multiple disease pathways triggered by septic injury. Cell therapies migh
Autor:
Keyue Shen, Martin L. Yarmush, Ryan Murray, Biju Parekkadan, Kevin E. Conway, Ralph Weissleder, Jessica S Elman, Shan Gao, Bakhos A. Tannous, Fangjing Wang
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89882 (2014)
PLoS ONE
PLoS ONE
Transient cell therapy is an emerging drug class that requires new approaches for pharmacological monitoring during use. Human mesenchymal stem cells (MSCs) are a clinically-tested transient cell therapeutic that naturally secrete anti-inflammatory f