Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jessica S. Bolton"'
Autor:
Jessica S. Bolton, Randall S. MacGill, Emily Locke, Jason A. Regules, Elke S. Bergmann-Leitner
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionPre-erythrocytic malaria vaccines hold the promise of inducing sterile protection thereby preventing the morbidity and mortality associated with Plasmodium infection. The main surface antigen of P. falciparum sporozoites, i.e., the circum
Externí odkaz:
https://doaj.org/article/0ade5144f61c4c5a99b1bb4130173d62
Autor:
Shikha Shrivastava, Joshua M. Carmen, Zhongyan Lu, Shraddha Basu, Rajeshwer S. Sankhala, Wei-Hung Chen, Phuong Nguyen, William C. Chang, Jocelyn King, Courtney Corbitt, Sandra Mayer, Jessica S. Bolton, Alexander Anderson, Isabella Swafford, Guillermo D. Terriquez, Hung V. Trinh, Jiae Kim, Ousman Jobe, Dominic Paquin-Proulx, Gary, R. Matyas, Gregory D. Gromowski, Jeffrey R. Currier, Elke Bergmann-Leitner, Kayvon Modjarrad, Nelson L. Michael, M. Gordon Joyce, Allison M. W. Malloy, Mangala Rao
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-17 (2023)
Abstract This study demonstrates the impact of adjuvant on the development of T follicular helper (Tfh) and B cells, and their influence on antibody responses in mice vaccinated with SARS-CoV-2-spike-ferritin-nanoparticle (SpFN) adjuvanted with eithe
Externí odkaz:
https://doaj.org/article/d8f58b2e3b264c9caf318f2cc61ee799
Autor:
Joshua M. Carmen, Shikha Shrivastava, Zhongyan Lu, Alexander Anderson, Elaine B. Morrison, Rajeshwer S. Sankhala, Wei-Hung Chen, William C. Chang, Jessica S. Bolton, Gary R. Matyas, Nelson L. Michael, M. Gordon Joyce, Kayvon Modjarrad, Jeffrey R. Currier, Elke Bergmann-Leitner, Allison M. W. Malloy, Mangala Rao
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-18 (2021)
Abstract The emergence of variants of concern, some with reduced susceptibility to COVID-19 vaccines underscores consideration for the understanding of vaccine design that optimizes induction of effective cellular and humoral immune responses. We ass
Externí odkaz:
https://doaj.org/article/1e6ad3a6c4204cd083ca84b3ba93c735
Autor:
Elke S. Bergmann-Leitner, Alexander G. Bobrov, Jessica S. Bolton, Michael D. Rouse, Lanier Heyburn, Radmila Pavlovic, Brittany I. Garry, Yonas Alamneh, Joseph Long, Brett Swierczewski, Stuart Tyner, Derese Getnet, Venkatasivasai S. Sajja, Vlado Antonic
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Explosive devices, either conventional or improvised, are common sources of injuries during combat, civil unrest, and terror attacks, resulting in trauma from exposure to blast. A blast wave (BW), a near-instantaneous rise in pressure followed by a n
Externí odkaz:
https://doaj.org/article/4712846560af4dd1aab09c9248d4237f
Autor:
Jessica S. Bolton, Sidhartha Chaudhury, Sheetij Dutta, Scott Gregory, Emily Locke, Tony Pierson, Elke S. Bergmann-Leitner
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-13 (2020)
Abstract Background Profiling immune responses induced by either infection or vaccination can provide insight into identification of correlates of protection. Furthermore, profiling of serological responses can be used to identify biomarkers indicati
Externí odkaz:
https://doaj.org/article/0fa132939bea4e1e8227f8a20908aa39
Autor:
Marie Mura, Pinyi Lu, Tanmaya Atre, Jessica S. Bolton, Elizabeth H. Duncan, Sidhartha Chaudhury, Elke S. Bergmann-Leitner
Publikováno v:
Vaccines, Vol 10, Iss 1, p 124 (2022)
Immune correlates of protection remain elusive for most vaccines. An identified immune correlate would accelerate the down-selection of vaccine formulations by reducing the need for human pathogen challenge studies that are currently required to dete
Externí odkaz:
https://doaj.org/article/a0b8b8246dae492b80b7c6e0b6f6cbd2
Autor:
Sidhartha Chaudhury, Jessica S. Bolton, Leigh Anne Eller, Merlin Robb, Julie Ake, Viseth Ngauy, Jason A. Regules, Edwin Kamau, Elke S. Bergmann-Leitner
Publikováno v:
Journal of Clinical Medicine; Volume 11; Issue 7; Pages: 1839
Reliably assessing exposure to mosquitoes carrying malaria parasites continues to be a challenge due to the lack of reliable, highly sensitive diagnostics with high-throughput potential. Here, we describe an approach that meets these requirements by
Autor:
Edwin Kamau, Sidhartha Chaudhury, Jessica S Bolton, Bonnie M Slike, Ningbo Jian, Michael A Eller, Leigh Anne Eller, Julie Ake, Merlin L Robb, Shelly J Krebs, Elke S Bergmann-Leitner
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 75(10)
Human immunodeficiency virus (HIV) and malaria infection rates overlap across sub-Saharan Africa, but factors influencing their co-occurrence are unclear. In a case-control study, we investigated whether malaria exposure increases risk of type 1 (HIV
Autor:
Elke S. Bergmann-Leitner, Alexander R. A. Anderson, Shikha Shrivastava, Allison M. W. Malloy, M. Gordon Joyce, Gary R. Matyas, Joshua M. Carmen, Elaine B. Morrison, Wei-Hung Chen, Rajeshwer S. Sankhala, William C. Chang, Zhongyan Lu, Nelson L. Michael, Jeffrey R. Currier, Mangala Rao, Jessica S Bolton, Kayvon Modjarrad
Potent cellular responses to viral infections are pivotal for long -lived protection. Evidence is growing that these responses are critical in SARS -CoV-2 immunity. Assessment of a SARS -CoV-2 spike ferritin nanoparticle (SpFN) immunogen paired with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e8623787e1bcb943b3902c9c4f37967
https://doi.org/10.1101/2021.04.28.441763
https://doi.org/10.1101/2021.04.28.441763
Autor:
Emily Locke, Daniel E. Neafsey, Sidhartha Chaudhury, Angela M. Early, Randall S. MacGill, Tony Pierson, Dyann F. Wirth, Elke S. Bergmann-Leitner, Jessica S. Bolton, C. Richter King
Publikováno v:
Vaccine. 39(6)
The circumsporozoite protein (CSP) is the main surface antigen of malaria sporozoites, a prime vaccine target, and is known to have polymorphisms in the C-terminal region. Vaccines using a single allele may have lower efficacy against genotypic varia