Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jessica R. Lou"'
Autor:
Reena Mukhiya, Wim A. Fleischmann, Jessica R. Loughland, Jo-Anne Chan, Fabian de Labastida Rivera, Dean Andrew, James G. Beeson, James S. McCarthy, Bridget E. Barber, J. Alejandro Lopez, Christian Engwerda, Richard Thomson-Luque, Michelle J. Boyle
Publikováno v:
EBioMedicine, Vol 109, Iss , Pp 105419- (2024)
Summary: Background: Human immune responses to infection and vaccination are heterogenous, driven by multiple factors including genetics, environmental exposures and personal infection histories. For malaria caused by Plasmodium falciparum parasites,
Externí odkaz:
https://doaj.org/article/61b334fc1a284054a6f4ac3e995a4b50
Autor:
Nicholas L. Dooley, Tinashe G. Chabikwa, Zuleima Pava, Jessica R. Loughland, Julianne Hamelink, Kiana Berry, Dean Andrew, Megan S. F. Soon, Arya SheelaNair, Kim A. Piera, Timothy William, Bridget E. Barber, Matthew J. Grigg, Christian R. Engwerda, J. Alejandro Lopez, Nicholas M. Anstey, Michelle J. Boyle
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Plasmodium falciparum malaria drives immunoregulatory responses across multiple cell subsets, which protects from immunopathogenesis, but also hampers the development of effective anti-parasitic immunity. Understanding malaria induced tolero
Externí odkaz:
https://doaj.org/article/d4f0ae647bca412fa846c8d4ab492791
Autor:
Yulin Wang, Fabian De Labastida Rivera, Chelsea L. Edwards, Teija C.M. Frame, Jessica A. Engel, Luzia Bukali, Jinrui Na, Susanna S. Ng, Dillon Corvino, Marcela Montes de Oca, Patrick T. Bunn, Megan S.F. Soon, Dean Andrew, Jessica R. Loughland, Jia Zhang, Fiona H. Amante, Bridget E. Barber, James S. McCarthy, J. Alejandro Lopez, Michelle J. Boyle, Christian R. Engwerda
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 19 (2023)
The development of highly effective malaria vaccines and improvement of drug-treatment protocols to boost antiparasitic immunity are critical for malaria elimination. However, the rapid establishment of parasite-specific immune regulatory networks fo
Externí odkaz:
https://doaj.org/article/3c2a3ba4c5594fffbb78ac8fa7298d0d
Autor:
Jessica R. Lou, Xiao Xi Zhang, Jie Zheng, Wei Qun Ding, Doris M. Benbrook, Marie H. Hanigan, Stuart E. Lind
Publikováno v:
Cancer Letters. 298:186-194
A variety of metal-binding compounds have been found to exert anti-cancer activity. We postulated that N-acetylcysteine (NAC), which is a membrane-permeable metal-binding compound, might have anti-cancer activity in the presence of metals. We found t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac22b07be64451bc18c5f2484ba1d630
https://doi.org/10.1016/j.canlet.2010.07.003
https://doi.org/10.1016/j.canlet.2010.07.003
Autor:
Charles T. Beavers, Michael A. Ihnat, Jessica R. Lou, Wei Qun Ding, Erin Tuller, Doris M. Benbrook
Publikováno v:
Molecular Pharmacology. 76:588-595
Docosahexaenoic acid (DHA; n-3, 22:6) is known to have anticancer activity, but its mechanisms of action remain to be further elucidated. We recently demonstrated that DHA down-regulates superoxide dismutase (SOD) 1 gene expression, thereby weakening
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcfe426016cf467468f0173d46acd896
https://doi.org/10.1124/mol.109.057430
https://doi.org/10.1124/mol.109.057430
Publikováno v:
Biochemical Pharmacology. 77:1480-1486
This study investigated the involvement of PPARgamma and PPARalpha signaling in the synergistic anticancer activity of clioquinol (5-chloro-7-iodo-8-hydroxyquinoline) and docosahexaenoic acid (DHA) in human cancer cells. The synergistic cytotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15a59f2e16b8477dd2356cc4d5508cca
https://doi.org/10.1016/j.bcp.2009.02.002
https://doi.org/10.1016/j.bcp.2009.02.002
Autor:
Jo-Anne Chan, Jessica R. Loughland, Lauren de la Parte, Satomi Okano, Isaac Ssewanyana, Mayimuna Nalubega, Felistas Nankya, Kenneth Musinguzi, John Rek, Emmanuel Arinaitwe, Peta Tipping, Peter Bourke, Dean Andrew, Nicholas Dooley, Arya SheelaNair, Bruce D. Wines, P. Mark Hogarth, James G. Beeson, Bryan Greenhouse, Grant Dorsey, Moses Kamya, Gunter Hartel, Gabriela Minigo, Margaret Feeney, Prasanna Jagannathan, Michelle J. Boyle
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Despite being key drivers of protective antibodies against malaria, little is known regarding the host and parasite factors that influence CD4 T-follicular helper cell and antibody development. Authors utilise samples from a study of children living
Externí odkaz:
https://doaj.org/article/cbf04ed2b51b46b3bbb1c106a6ca7595
Autor:
Chelsea L. Edwards, Susanna S. Ng, Fabian de Labastida Rivera, Dillon Corvino, Jessica A. Engel, Marcela Montes de Oca, Luzia Bukali, Teija C.M. Frame, Patrick T. Bunn, Shashi Bhushan Chauhan, Siddharth Sankar Singh, Yulin Wang, Jinrui Na, Fiona H. Amante, Jessica R. Loughland, Megan S.F. Soon, Nicola Waddell, Pamela Mukhopadhay, Lambros T. Koufariotis, Rebecca L. Johnston, Jason S. Lee, Rachel Kuns, Ping Zhang, Michelle J. Boyle, Geoffrey R. Hill, James S. McCarthy, Rajiv Kumar, Christian R. Engwerda
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 4 (2023)
Externí odkaz:
https://doaj.org/article/1c7a7aac042d489a8d9ce7e4e35f9dc0
Publikováno v:
International journal of pharmaceutical compounding. 18(4)
Cases of contaminated nonsterile products have been reported in increasing numbers. Often, these contaminated products are associated with the presence of objectionable microorganisms. The major contaminants of nonsterile pharmaceutical products and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e9ce825beb55446db47f4f372d136aa4
https://pubmed.ncbi.nlm.nih.gov/25474859
https://pubmed.ncbi.nlm.nih.gov/25474859
Publikováno v:
International journal of pharmaceutical compounding. 18(3)
Contamination of pharmaceuticals with microorganisms may lead to deleterious effects on the therapeutic properties of the drug, and may potentially cause injuries to intended recipients. Cases of contaminated nonsterile products have been reported in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::526b2155e5ce02678a8e896a1e5c75e5
https://pubmed.ncbi.nlm.nih.gov/25306769
https://pubmed.ncbi.nlm.nih.gov/25306769