Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jessica R. Doll"'
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102643- (2023)
Summary: Inflammation-driven preterm birth (PTB) is modeled in mice using lipopolysaccharide (LPS) challenge. Here, we present a protocol for cytokine and uterine immune cell characterization in a mouse model of LPS-induced PTB. We describe steps for
Externí odkaz:
https://doaj.org/article/9a67d7e0a6fe48a394a639ab4a64b52e
Autor:
Jessica R. Doll, Maria E. Moreno-Fernandez, Traci E. Stankiewicz, Jennifer L. Wayland, Adrienne Wilburn, Benjamin Weinhaus, Claire A. Chougnet, Daniela Giordano, Monica Cappelletti, Pietro Presicce, Suhas G. Kallapur, Nathan Salomonis, Tamara Tilburgs, Senad Divanovic
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112352- (2023)
Summary: Clinical evidence points to a function for B cell-activating factor (BAFF) in pregnancy. However, direct roles for BAFF-axis members in pregnancy have not been examined. Here, via utility of genetically modified mice, we report that BAFF pro
Externí odkaz:
https://doaj.org/article/59d828a84fe34ca5847dca21b989426e
Aging mitigates the severity of obesity-associated metabolic sequelae in a gender independent manner
Autor:
Maria E. Moreno-Fernandez, Vishakha Sharma, Traci E. Stankiewicz, Jarren R. Oates, Jessica R. Doll, Michelle S. M. A. Damen, Maha A. T. A. Almanan, Claire A. Chougnet, David A. Hildeman, Senad Divanovic
Publikováno v:
Nutrition & Diabetes, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Background Understanding gender-associated bias in aging and obesity-driven metabolic derangements has been hindered by the inability to model severe obesity in female mice. Methods Here, using chow- or high fat diet (HFD)-feeding regimens a
Externí odkaz:
https://doaj.org/article/7d0c748d3a344ab1a14d117f2eb1e4a9
Autor:
Calvin C. Chan, Isaac T. W. Harley, Paul T. Pfluger, Aurelien Trompette, Traci E. Stankiewicz, Jessica L. Allen, Maria E. Moreno-Fernandez, Michelle S. M. A. Damen, Jarren R. Oates, Pablo C. Alarcon, Jessica R. Doll, Matthew J. Flick, Leah M. Flick, Joan Sanchez-Gurmaches, Rajib Mukherjee, Rebekah Karns, Michael Helmrath, Thomas H. Inge, Stuart P. Weisberg, Sünje J. Pamp, David A. Relman, Randy J. Seeley, Matthias H. Tschöp, Christopher L. Karp, Senad Divanovic
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Interactions between the immune system and adipose tissue contribute to the regulation of body weight, however, the underlying mechanisms remain incompletely understood. Here the authors dissect the role of two structurally and functionally similar i
Externí odkaz:
https://doaj.org/article/1874a0fdf3df440c914731f67be8205d
Autor:
Calvin C. Chan, Michelle S. M. A. Damen, Maria E. Moreno-Fernandez, Traci E. Stankiewicz, Monica Cappelletti, Pablo C. Alarcon, Jarren R. Oates, Jessica R. Doll, Rajib Mukherjee, Xiaoting Chen, Rebekah Karns, Matthew T. Weirauch, Michael A. Helmrath, Thomas H. Inge, Senad Divanovic
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
White adipose inflammation can occur in obesity and is at least in part mediated by inflammatory immune cells. Here the authors show that the Type I Interferon/Interferon alpha-beta receptor axis promotes an inflammatory, glycolysis associated adipoc
Externí odkaz:
https://doaj.org/article/d7769e000a41416a858c145b467956f7
Autor:
Monica Cappelletti, Jessica R. Doll, Traci E. Stankiewicz, Matthew J. Lawson, Vivien Sauer, Bingqiang Wen, Vladimir V. Kalinichenko, Xiaofei Sun, Tamara Tilburgs, Senad Divanovic
Publikováno v:
JCI Insight, Vol 5, Iss 22 (2020)
Infection-driven inflammation in pregnancy is a major cause of spontaneous preterm birth (PTB). Both systemic infection and bacterial ascension through the vagina/cervix to the amniotic cavity are strongly associated with PTB. However, the contributi
Externí odkaz:
https://doaj.org/article/bd2f0c1a6a2e41528ce78f3b2d2a01fe
Autor:
Se-Hyung Park, Michelle S M A Damen, Samir Softic, Senad Divanovic, De’Broski R. Herbert, Sara Szabo, Calvin C. Chan, Traci E. Stankiewicz, Jessica R Doll, Robert N. Helsley, Maria E. Moreno-Fernandez
Publikováno v:
International Journal of Obesity (2005)
ObjectiveThe risks of excess sugar intake in addition to high-fat diet consumption on immunopathogenesis of obesity-associated metabolic diseases are poorly defined. Interleukin-4 (IL-4) and IL-13 signaling via IL-4Rα regulates adipose tissue lipoly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b224bcba79e770fcc5d4a636a95b0bf9
https://doi.org/10.1038/s41366-021-00902-6
https://doi.org/10.1038/s41366-021-00902-6
Aging mitigates the severity of obesity-associated metabolic sequelae in a gender independent manner
Autor:
Jessica R Doll, Claire A. Chougnet, Traci E. Stankiewicz, Maria E. Moreno-Fernandez, Vishakha Sharma, Jarren R Oates, Senad Divanovic, Maha Almanan, David A. Hildeman, Michelle S M A Damen
Publikováno v:
Nutrition & Diabetes, Vol 11, Iss 1, Pp 1-13 (2021)
Nutrition & Diabetes
Nutrition & Diabetes
Background Understanding gender-associated bias in aging and obesity-driven metabolic derangements has been hindered by the inability to model severe obesity in female mice. Methods Here, using chow- or high fat diet (HFD)-feeding regimens at standar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755cd3d83aa69df30b160525678d5b2f
https://doaj.org/article/7d0c748d3a344ab1a14d117f2eb1e4a9
https://doaj.org/article/7d0c748d3a344ab1a14d117f2eb1e4a9
Autor:
Maria E. Moreno-Fernandez, Michelle S M A Damen, Isaac T.W. Harley, Joan Sanchez-Gurmaches, David A. Relman, Stuart P. Weisberg, Pablo C Alarcon, Matthew J. Flick, Matthias H. Tschöp, Calvin C. Chan, Aurelien Trompette, Rajib Mukherjee, Christopher L. Karp, Randy J. Seeley, Traci E. Stankiewicz, Leah M. Flick, Paul T. Pfluger, Jessica R Doll, Sünje Johanna Pamp, Michael A. Helmrath, Senad Divanovic, Thomas H. Inge, Jarren R Oates, Jessica L. Allen, Rebekah Karns
Publikováno v:
Nature Communications
Chan, C C, Harley, I T W, Pfluger, P T, Trompette, A, Stankiewicz, T E, Allen, J L, Moreno-Fernandez, M E, Damen, M S M A, Oates, J R, Alarcon, P C, Doll, J R, Flick, M J, Flick, L M, Sanchez-Gurmaches, J, Mukherjee, R, Karns, R, Helmrath, M, Inge, T H, Weisberg, S P, Pamp, S J, Relman, D A, Seeley, R J, Tschöp, M H, Karp, C L & Divanovic, S 2021, ' A BAFF/APRIL axis regulates obesogenic diet-driven weight gain ', Nature Communications, vol. 12, no. 1, 2911 . https://doi.org/10.1038/s41467-021-23084-1
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nat. Commun. 12:2911 (2021)
Chan, C C, Harley, I T W, Pfluger, P T, Trompette, A, Stankiewicz, T E, Allen, J L, Moreno-Fernandez, M E, Damen, M S M A, Oates, J R, Alarcon, P C, Doll, J R, Flick, M J, Flick, L M, Sanchez-Gurmaches, J, Mukherjee, R, Karns, R, Helmrath, M, Inge, T H, Weisberg, S P, Pamp, S J, Relman, D A, Seeley, R J, Tschöp, M H, Karp, C L & Divanovic, S 2021, ' A BAFF/APRIL axis regulates obesogenic diet-driven weight gain ', Nature Communications, vol. 12, no. 1, 2911 . https://doi.org/10.1038/s41467-021-23084-1
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nat. Commun. 12:2911 (2021)
The impact of immune mediators on weight homeostasis remains underdefined. Interrogation of resistance to diet-induced obesity in mice lacking a negative regulator of Toll-like receptor signaling serendipitously uncovered a role for B cell activating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::263f2646adf0ada712afeb8ddda964b2
https://doi.org/10.1038/s41467-021-23084-1
https://doi.org/10.1038/s41467-021-23084-1
Autor:
Michelle S M A Damen, Maria E. Moreno-Fernandez, Stavra A. Xanthakos, Lindsey E. Romick-Rosendale, Nathan Salomonis, Amy S. Shah, Kashish Chetal, Daniel A. Giles, Sara Szabo, Michael A. Helmrath, Jarren R Oates, Calvin C. Chan, Traci E. Stankiewicz, Thomas H. Inge, Xiaoting Chen, Jessica R Doll, Rebekah Karns, Senad Divanovic, Rachel Sheridan, Hitesh Deshmukh, Matthew T. Weirauch
Publikováno v:
Cell Metab
Emerging evidence suggests a key contribution to non-alcoholic fatty liver disease (NAFLD) pathogenesis by Th17 cells. The pathogenic characteristics and mechanisms of hepatic Th17 cells, however, remain unknown. Here, we uncover and characterize a d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e9f8c394017d703a607992701ff8f7
https://europepmc.org/articles/PMC8237408/
https://europepmc.org/articles/PMC8237408/
