Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jessica R. Bame"'
Autor:
Michael Jirasek, Abhishek Sharma, Jessica R. Bame, S. Hessam M. Mehr, Nicola Bell, Stuart M. Marshall, Cole Mathis, Alasdair MacLeod, Geoffrey J. T. Cooper, Marcel Swart, Rosa Mollfulleda, Leroy Cronin
Publikováno v:
ACS Central Science, Vol 10, Iss 5, Pp 1054-1064 (2024)
Externí odkaz:
https://doaj.org/article/a200dd341b7f40ffa1127bd0f1ffcfcd
Publikováno v:
Angewandte Chemie International Edition. 62
Autor:
Craig P. Butts, Casper Hoeck, Christof M. Jäger, M.J. Carrington, Jessica R. Bame, Anna K. Croft
Publikováno v:
Bame, J, Hoeck, C, Carrington, M J, Butts, C P, Jäger, C M & Croft, A K 2018, ' Improved NOE fitting for flexible molecules based on molecular mechanics data-a case study with : S-adenosylmethionine ', Physical Chemistry Chemical Physics, vol. 20, no. 11, pp. 7523-7531 . https://doi.org/10.1039/c7cp07265a
The use of molecular dynamics (MD) calculations to derive relative populations of conformers is highly sensitive to both timescale and parameterisation of the MD. Where these calculations are coupled with NOE data to determine the dynamics of a molec
Autor:
Aviram Kogot-Levin, Joo Won Park, Racheli Erez-Roman, Boaz Tirosh, Jessica R. Bame, Alfred H. Merrill, Yael Pewzner-Jung, Anthony H. Futerman, Woo Jae Park, Ann Saada
Publikováno v:
Journal of Biological Chemistry. 288:30904-30916
Very long chain (C22-C24) ceramides are synthesized by ceramide synthase 2 (CerS2). A CerS2 null mouse displays hepatopathy because of depletion of C22-C24 ceramides, elevation of C16-ceramide, and/or elevation of sphinganine. Unexpectedly, CerS2 nul
Autor:
Jessica R. Bame, Alfred H. Merrill, Kostantin Dobrenis, Jingjing Duan, Samuel Kelly, Tamar Farfel-Becker, Einat B. Vitner, Vera Shinder, Anthony H. Futerman
Publikováno v:
Human Molecular Genetics. 23:843-854
Gaucher disease has recently received wide attention due to the unexpected discovery that it is a genetic risk factor for Parkinson's disease. Gaucher disease is caused by the defective activity of the lysosomal enzyme, glucocerebrosidase (GCase; GBA
Autor:
Russell J. Cox, Thomas J. Simpson, Jessica R. Bame, Catharine R. Jones, James W. Marshall, Mark D. Greenhalgh, Craig P. Butts
Publikováno v:
Jones, C R, Greenhalgh, M D, Bame, J R, Simpson, T J, Cox, R J, Marshall, J W & Butts, C P 2016, ' Subtle temperature-induced changes in small molecule conformer dynamics-observed and quantified by NOE spectroscopy ', Chemical Communications, vol. 52, no. 14, pp. 2920-2923 . https://doi.org/10.1039/c5cc10509a
NOE–distance relationships are shown to be sufficiently accurate to monitor very small changes in conformer populations in response to temperature (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b647f5a22ef44aa8d241c7169ace363
https://research-information.bris.ac.uk/ws/files/83548945/c5cc10509a.pdf
https://research-information.bris.ac.uk/ws/files/83548945/c5cc10509a.pdf
Autor:
Varinder K. Aggarwal, Sebastien Balieu, Jeremy N. Harvey, Jessica R. Bame, Craig P. Butts, Matthew P. Webster, Stephanie P. Bull, James Dale, Matthew Burns, Stephanie Essafi
Publikováno v:
Nature
Nature, Nature Publishing Group, 2014, 513, pp.183-188. ⟨10.1038/nature13711⟩
Nature, Nature Publishing Group, 2014, 513, pp.183-188. ⟨10.1038/nature13711⟩
International audience; Molecular ‘assembly lines’, in which organic molecules undergo iterative processes such as chain elongation and functional group manipulation, are found in many natural systems, including polyketide biosynthesis. Here we r
Autor:
Nadja B. Cech, Tamam El-Elimat, Jessica R. Bame, Joseph O. Falkinham, R. Owen Bussey, Hiyas A. Junio, Richard A. Cech, Nicholas H. Oberlies, Tyler N. Graf, Scott A. Jarmusch
An Alkanna orientalis leaf and flower extract inhibited the growth of Staphylococcus aureus, a pathogen that causes an estimated 478 000 hospitalizations in the US annually. Bioassay-guided fractionation of A. orientalis resulted in isolation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25150ad60413add16f0287e2d30cb571
https://europepmc.org/articles/PMC4527991/
https://europepmc.org/articles/PMC4527991/