Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jessica Plescia"'
Publikováno v:
ARKIVOC, Vol 2019, Iss 4, Pp 280-298 (2019)
Externí odkaz:
https://doaj.org/article/0cd7dd09f8ea43a9836cfa361b939f2d
Autor:
Justin M. Di Trani, Stephane De Cesco, Rebecca O’Leary, Jessica Plescia, Claudia Jorge do Nascimento, Nicolas Moitessier, Anthony K. Mittermaier
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
There is growing evidence that the kinetics of interactions between inhibitors and their targets can strongly impact therapeutic efficacy. Here the authors describe an isothermal titration calorimetry-based method that can rapidly quantify inhibition
Externí odkaz:
https://doaj.org/article/695ef23f7e8d4d87a44cc9ad450d7ebc
Autor:
Jessica Plescia, Damien Hédou, Maud Eva Pousse, Anne Labarre, Caroline Dufresne, Anthony Mittermaier, Nicolas Moitessier
Publikováno v:
European journal of medicinal chemistry. 240
We have previously described several different chemical series of bicyclic prolyl oligopeptidase (POP) inhibitors as probes for neurodegenerative diseases that demonstrated nanomolar activity in vitro and submicromolar activity in cellulo. The more r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1474d42ec3f8327a4986fd713a8e9dd8
https://pubmed.ncbi.nlm.nih.gov/35797897
https://pubmed.ncbi.nlm.nih.gov/35797897
Autor:
Julia K. Stille, Jevgenijs Tjutrins, Guanyu Wang, Felipe A. Venegas, Christopher Hennecker, Andrés M. Rueda, Itai Sharon, Nicole Blaine, Caitlin E. Miron, Sharon Pinus, Anne Labarre, Jessica Plescia, Mihai Burai Patrascu, Xiaocong Zhang, Alexander S. Wahba, Danielle Vlaho, Mitchell J. Huot, T. Martin Schmeing, Anthony K. Mittermaier, Nicolas Moitessier
Publikováno v:
European Journal of Medicinal Chemistry
Severe diseases such as the ongoing COVID-19 pandemic, as well as the previous SARS and MERS outbreaks, are the result of coronavirus infections and have demonstrated the urgent need for antiviral drugs to combat these deadly viruses. Due to its esse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e1caa31a79967b02adbbfb04cbc82d5
http://europepmc.org/articles/PMC8665847
http://europepmc.org/articles/PMC8665847
Autor:
Julia Stille, Jevgenijs Tjutrins, Guanyu Wang, Felipe A. Venegas, Christopher Hennecker, Andres Mauricio Rueda, Itai Sharon, Nicole Blaine, Caitlin E. Miron, Sharon Pinus, Anne Labarre, Jessica Plescia, Mihai Burai Patrascu, Xiaocong Zhang, Alexander S. Wahba, Danielle Vlaho, Mitchell Huot, T. Martin Schmeing, Anthony K Mittermaier, Nicolas Moitessier
Severe diseases such as the ongoing COVID-19 pandemic, as well as the previous SARS and MERS outbreaks, are the result of coronavirus infections and have demonstrated the urgent need for antiviral drugs to combat these deadly viruses. Due to its esse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a36d8047a6c9ad0b9b6ffb8666e7f58
https://doi.org/10.33774/chemrxiv-2021-5twk7-v3
https://doi.org/10.33774/chemrxiv-2021-5twk7-v3
Autor:
Jessica Plescia, Caroline Dufresne, Anthony Mittermaier, Maud Pousse, Damien Hedou, Anne Labarre, Nicolas Moitessier
We have previously described several different chemical series of bicyclic prolyl oligopeptidase (POP) inhibitors as probes for neurodegenerative diseases that demonstrated nanomolar activity in vitro and submicromolar activity in cellulo. The more r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26bb1084a10ae55e0136c77279fa929a
https://doi.org/10.33774/chemrxiv-2021-2x1d1
https://doi.org/10.33774/chemrxiv-2021-2x1d1
Autor:
Jessica Plescia, Nicolas Moitessier, Amit S. Kalgutkar, Mihai Burai Patrascu, Vincent Mascitti
Publikováno v:
ARKIVOC, Vol 2019, Iss 4, Pp 280-298 (2019)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3c9aab2b579609fbe65634967c1baf
https://doi.org/10.24820/ark.5550190.p010.970
https://doi.org/10.24820/ark.5550190.p010.970
Autor:
Kevin McBride, Patricia Laplante, Caitlin E. Miron, Julie A. Ross, Nicolas Moitessier, Jessica Plescia, Tarik Möröy
Publikováno v:
European journal of medicinal chemistry. 213
The MYC oncogene is considered to be a high priority target for clinical intervention in cancer patients due to its aberrant activation in more than 50% of human cancers. Direct small molecule inhibition of MYC has traditionally been hampered by its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eac6f51f71390275f284ce6468457f83
https://pubmed.ncbi.nlm.nih.gov/33460833
https://pubmed.ncbi.nlm.nih.gov/33460833
Autor:
Julia Stille, Jevgenijs Tjutrins, Guanyu Wang, Felipe A. Venegas, Christopher Hennecker, Andres Mauricio Rueda, Caitlin E. Miron, Sharon Pinus, Anne Labarre, Jessica Plescia, Mihai Burai Patrascu, Danielle Vlaho, Mitchell Huot, Anthony K Mittermaier, Nicolas Moitessier
Severe diseases such as the ongoing COVID-19 pandemic, as well as the previous SARS and MERS outbreaks, are the result of coronavirus infections and have demonstrated the urgent need for antiviral drugs to combat these deadly viruses. Due to its esse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b917bcf453eb7c43395b652c44f04f9
https://doi.org/10.26434/chemrxiv.13087742.v1
https://doi.org/10.26434/chemrxiv.13087742.v1
Autor:
Caroline Dufresne, Naëla Janmamode, Nicolas Moitessier, Alexander S. Wahba, Anthony Mittermaier, Jessica Plescia
Publikováno v:
European journal of medicinal chemistry. 185
Over the past decade, many drug discovery endeavors have been invested in targeting the serine proteases prolyl oligopeptidase (POP) for the treatment of Alzheimer's and Parkinson's disease and, more recently, epithelial cancers. Our research group h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecf649fd52a95299fc41738cee0528dc
https://pubmed.ncbi.nlm.nih.gov/31732257
https://pubmed.ncbi.nlm.nih.gov/31732257