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pro vyhledávání: '"Jessica Pilar McLin"'
Autor:
Jessica Pilar McLin, Leslie Michels Thompson, Aldons J. Lusis, Richard C. Davis, Oswald Steward
Publikováno v:
Neurobiology of Disease, Vol 29, Iss 3, Pp 391-399 (2008)
Previous studies have provided evidence that a quantitative trait locus (QTL) on the distal part of chromosome 18 (chr18) is a major determinant of vulnerability to hippocampal neurodegeneration following kainic acid (KA)-induced seizures in inbred m
Externí odkaz:
https://doaj.org/article/f59fdd7df1ad4fb59e4a0838dfecb1cf
Publikováno v:
Neurobiology of Disease, Vol 29, Iss 3, Pp 391-399 (2008)
Previous studies have provided evidence that a quantitative trait locus (QTL) on the distal part of chromosome 18 (chr18) is a major determinant of vulnerability to hippocampal neurodegeneration following kainic acid (KA)-induced seizures in inbred m
Publikováno v:
The European journal of neuroscience. 24(11)
In mice, the genetic background determines susceptibility to hippocampal neurodegeneration induced by the excitotoxin kainic acid (KA). If genetic background plays as significant a role in the striatum, the area most affected in Huntington's disease
Autor:
Oswald Steward, Jessica Pilar McLin
Publikováno v:
The European journal of neuroscience. 24(8)
We assessed inbred, outbred and hybrid mouse strains for susceptibility to seizures and neurodegeneration induced by systemic administration of kainic acid (KA). Each strain showed a unique pattern of susceptibility to seizures as assessed by the dos