Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jessica Pierre Francois"'
Autor:
Margot Ernst, Werner Sieghart, Nathalie Y. R. Agar, Kashi Reddy Methuku, Robert Langer, Oliver Jonas, Michael M. Poe, Armen Changelian, Soma Sengupta, Michael J. Cima, Jessica Pierre Francois, Daniel Pomeranz Krummel, Frank Tranghese, Scott L. Pomeroy, David Calligaris, James M. Cook
Publikováno v:
Journal of Biomedical Nanotechnology. 12:1297-1302
Medulloblastoma is the most common childhood malignant brain tumor. The most lethal medulloblastoma subtype exhibits a high expression of the GABAA receptor α5 subunit gene and MYC amplification. New benzodiazepines have been synthesized to function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8628ba8c771bf0d7d2965f5d9d306605
https://doi.org/10.1166/jbn.2016.2262
https://doi.org/10.1166/jbn.2016.2262
Autor:
Vladimir Amani, Natalia Teider, Judith A. Steen, Jessica Pierre-Francois, Peter G. Warren, Marc Remke, Stefan M. Pfister, Min Jeong Kye, Shyamal Dilhan Weeraratne, Yoon Jae Cho, Scott L. Pomeroy, Tenley C. Archer, Dominic Winter, Alfa H.C. Bai, Soma Sengupta
Publikováno v:
Acta Neuropathologica. 123:539-552
Medulloblastomas are the most common malignant brain tumors in children. Several large-scale genomic studies have detailed their heterogeneity, defining multiple subtypes with unique molecular profiles and clinical behavior. Increased expression of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607792c622e145ad48e75b481f995731
https://doi.org/10.1007/s00401-012-0969-5
https://doi.org/10.1007/s00401-012-0969-5
Autor:
Kristian Cibulskis, Pablo Tamayo, Peter Lichter, David T.W. Jones, Furong Yu, Michael D. Taylor, Scott L. Pomeroy, Paul A. Northcott, Scott L. Carter, Niall J. Lennon, Jill P. Mesirov, Petar Stojanov, Tenley C. Archer, Amanda G. Kautzman, Vladimir Amani, Mauricio O. Carneiro, Daniel Auclair, Thomas M. Roberts, Heidi Greulich, Shyamal Dilhan Weeraratne, Andrey Sivachenko, Aaron McKenna, Gerald R. Crabtree, Gad Getz, Michael S. Lawrence, Stacey Gabriel, James Meldrim, Stefan M. Pfister, Yoon Jae Cho, Rachel L. Erlich, Natalie Jäger, Natalia Teider, Alex H. Ramos, Matthew Meyerson, Soma Sengupta, Jessica Pierre Francois, Michael G. Ross, James Bochicchio, Erica Shefler, Trevor J. Pugh, Brian Sogoloff, Carsten Russ, Daniel Pomeranz Krummel
Publikováno v:
Nature
Nature, vol 488, iss 7409
Nature, vol 488, iss 7409
Medulloblastomas are the most common malignant brain tumors in children1. Identifying and understanding the genetic events that drive these tumors is critical for the development of more effective diagnostic, prognostic and therapeutic strategies. Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d3b8b4a2dc5a34e08ab4c3a11f5b4f
http://europepmc.org/articles/PMC3413789
http://europepmc.org/articles/PMC3413789
Autor:
Ernest Fraenkel, Jill P. Mesirov, Andrey Korshunov, Pablo Tamayo, James Jensen, Scott L. Pomeroy, Michael A. Gillette, Hailei Zhang, Marcel Kool, Colin J. Daniel, Divya Ramamoorthy, Lauren C. Tang, Jessica Pierre-Francois, Michael S. Noble, Alexander LeNail, Jonathan O. Lipton, D. R. Mani, Maxwell P. Gold, Rosalie C. Sears, Tobias Ehrenberger, Tenley C. Archer, Elizabeth L. Mahoney, Karsten Krug, Clarence K. Mah, Philipp Mertins, Filip Mundt, Paul A. Northcott, Jacob Silterra, Karl R. Clauser, Steven A. Carr, Stefan M. Pfister
Publikováno v:
Cancer cell, vol 34, iss 3
PMC
PMC
There is a pressing need to identify therapeutic targets in tumors with low mutation rates such as the malignant pediatric brain tumor medulloblastoma. To address this challenge, we quantitatively profiled global proteomes and phospho-proteomes of 45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f6fd78b41fabed227cd0495b673682
https://doi.org/10.1016/j.ccell.2018.08.004
https://doi.org/10.1016/j.ccell.2018.08.004
Autor:
James M. Cook, Nathalie Y. R. Agar, Kashi Reddy Methuku, Oliver Jonas, Michael M. Poe, Jessica Pierre Francois, David Calligaris, Soma Sengupta, Robert Langer, Scott L. Pomeroy
Publikováno v:
Neuro-Oncology. 16:v84-v84
INTRODUCTION: Neural tumors such as medulloblastomas, have distinct genetic signatures, including neurotransmitter receptors, indicative of their developmental lineage. Neurotransmitter receptors have been well-defined in normal neurophysiological, d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54cba5d6d2aedd5aaa822631db77d7f5
https://doi.org/10.1093/neuonc/nou255.24
https://doi.org/10.1093/neuonc/nou255.24
Publikováno v:
Cancer Research. 73:5241-5241
Medulloblastoma, the most common malignant pediatric brain tumor, comprises four subtypes classified by their distinct molecular signatures. Wnt and SHH subtypes up-regulate those respective signaling pathways, while Group 3 and Group 4 tumors are le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe26a887f4f89db1597ce314c03e2513
https://doi.org/10.1158/1538-7445.am2013-5241
https://doi.org/10.1158/1538-7445.am2013-5241