Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Jessica O Winter"'
Autor:
Ariel Robbins, Hazen Hildebolt, Michael Neuhoff, Peter Beshay, Jessica O. Winter, Carlos E. Castro, Ralf Bundschuh, Michael G. Poirier
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Biomolecular systems are dependent on a complex interplay of forces. Modern force spectroscopy techniques provide means of interrogating these forces, but they are not optimized for studies in constrained environments as they require attachm
Externí odkaz:
https://doaj.org/article/9d8b1719f3fd49ac8789b779e7d5820d
Autor:
Shreyas S Rao, Sarah Bentil, Jessica DeJesus, John Larison, Alex Hissong, Rebecca Dupaix, Atom Sarkar, Jessica O Winter
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35852 (2012)
Cells sense and respond to the rigidity of their microenvironment by altering their morphology and migration behavior. To examine this response, hydrogels with a range of moduli or mechanical gradients have been developed. Here, we show that edge eff
Externí odkaz:
https://doaj.org/article/8a7b3c4efca849ed88427e8140783a73
Autor:
Jessica O Winter, Shreyas Rao
The tumour microenvironment is increasingly recognized as an important contributor to cancer progression and treatment. However, most cancer studies continue to be performed in 2D tissue culture dishes that do not capture the characteristics of the t
Autor:
Yixiao Cui, Paul Lee, Jesse J. Reardon, Anna Wang, Skylar Lynch, Jose J. Otero, Gina Sizemore, Jessica O. Winter
Publikováno v:
Journal of Materials Chemistry B.
Glioblastoma cells co-cultured with astrocytes in col-HA hydrogels exhibit changes in migration patterns. 3D in vitro models using ECM mimetic materials can be used to analyze glioma-astrocyte crosstalk.
Autor:
Elizabeth Jergens, Silvio de Araujo Fernandes-Junior, Yixiao Cui, Ariel Robbins, Carlos E. Castro, Michael G. Poirier, Metin N. Gurcan, Jose J. Otero, Jessica O. Winter
Publikováno v:
Nanoscale.
Top: Schematic of DNA-caged nanoparticle composite formation. Bottom: U87 cells labeled with fluorescent DNA-caged nanoparticles before and after erasing with single stranded DNA. Scale bar = 10 μm.
Autor:
Jessica O. Winter, Shreyas S. Rao
Publikováno v:
Biomaterial Based Approaches to Study the Tumour Microenvironment ISBN: 9781839162848
This chapter introduces the application of tissue engineering to study disease pathology and treatment in the field of cancer. A general overview and history of tissue engineering is provided, with early examples of its application to cancer. Finally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8d3fd35f51f599454d87091a4e70632
https://doi.org/10.1039/9781839166013-00001
https://doi.org/10.1039/9781839166013-00001
Autor:
Elizabeth Jergens, Silvio de Araujo Fernandes-Junior, Yixiao Cui, Ariel Robbins, Carlos E. Castro, Michael G. Poirier, Metin N. Gurcan, Jose J. Otero, Jessica O. Winter
DNA-modified nanoparticles enable DNA sensing and therapeutics in nanomedicine and are also crucial for nanoparticle self-assembly with DNA-based materials. However, methods to conjugate DNA to nanoparticle surfaces are limited, inefficient, and lack
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77378c5753a07e6a4ca2440fd9e1d736
https://doi.org/10.1101/2022.11.07.515456
https://doi.org/10.1101/2022.11.07.515456
Publikováno v:
Frontiers in Biomaterials Science. 1
Sustainable food production is a grand challenge facing the global economy. Traditional agricultural practice requires numerous interventions, such as application of nutrients and pesticides, of which only a fraction are utilized by the target crop p
Autor:
Kil Ho Lee, Brenton A. Noesges, Chris McPherson, Faiz Khan, Leonard J. Brillson, Jessica O. Winter
Publikováno v:
Nanoscale. 14(32)
Most high-quality quantum dots (QDs) are synthesized in the organic phase, and are often coated with polymers for use in aqueous biological environments. QDs can exhibit fluorescence losses during phase transfer, but evaluating underlying mechanisms
Autor:
Jessica O. Winter
Publikováno v:
Science
To accelerate the translation of cancer nanomedicine, we used an integrated genomic approach to improve our understanding of the cellular processes governing nanoparticle trafficking. We developed a massively parallel screen leveraging barcoded, pool