Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jessica N. Filderman"'
Autor:
Jennifer L. Taylor, Kathleen M. Kokolus, Per H. Basse, Jessica N. Filderman, Chloe E. Cosgrove, Simon C. Watkins, Andrea Gambotto, Devin B. Lowe, Robert P. Edwards, Pawel Kalinski, Walter J. Storkus
Publikováno v:
Vaccines, Vol 12, Iss 7, p 777 (2024)
We previously reported that dendritic cell (DC)-based vaccines targeting antigens expressed by tumor-associated vascular endothelial cells (VECs) and pericytes effectively control tumor growth in translational mouse tumor models. In the current repor
Externí odkaz:
https://doaj.org/article/d89de03438f041a29bc5602044bdd7d6
Autor:
Jessica N. Filderman, Jennifer L. Taylor, Jianmin Wang, Yali Zhang, Prashant Singh, Mark A. Ross, Simon C. Watkins, Ayah Nedal Al Bzour, Lilit Karapetyan, Pawel Kalinski, Walter J. Storkus
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundStimulator of Interferon Genes (STING) is a dsDNA sensor that triggers type I inflammatory responses. Recent data from our group and others support the therapeutic efficacy of STING agonists applied intratumorally or systemically in a range
Externí odkaz:
https://doaj.org/article/3c0638960d42499caddb87b687f3e945
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 12 (2022)
Tumor-infiltrating lymphocytes (TILs) contain substantial numbers of CD4+ T cells mediating pro- and antitumor functions. While CD4+ Tregs are well characterized and known to promote tumor immune evasion, the fingerprint of CD4+ Th cells that recogni
Externí odkaz:
https://doaj.org/article/38db6302f5984895a63c6feccf8dcc1a
Autor:
Yan Lin, Lisa H Butterfield, Pawel Kalinski, Walter J Storkus, Hussein Tawbi, Ahmad Tarhini, John M Kirkwood, Ronald J Fecek, Fei Ding, Lauren Miller, Deena Maurer, Manoj Chelvanambi, Amy Rose, Jennifer L Taylor, Anamika Bose, Devin Lowe, Melissa DeMark, Lilit Karapetyan, Jessica N Filderman, Timothy J Looney, Elizabeth Linch, Geoffrey M Lowman
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/dcbb8fd4e95447ba88c7962ad61b4ed6
Autor:
Jessica N. Filderman, Mark Appleman, Manoj Chelvanambi, Jennifer L. Taylor, Walter J. Storkus
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Tertiary lymphoid structures (TLS), also known as ectopic lymphoid structures (ELS) or tertiary lymphoid organs (TLO), represent a unique subset of lymphoid tissues noted for their architectural similarity to lymph nodes, but which conditionally form
Externí odkaz:
https://doaj.org/article/6bae8bdeb7b8406a91f8206c17e917a9
Autor:
Jennifer L. Taylor, Hussein Abdul-Hassan Tawbi, Lauren Miller, Jessica N. Filderman, Timothy J. Looney, Manoj Chelvanambi, John M. Kirkwood, Yan Lin, Deena M. Maurer, Melissa DeMark, Lilit Karapetyan, Ronald J Fecek, Walter J. Storkus, Anamika Bose, Lisa H. Butterfield, Geoffrey Lowman, Elizabeth Linch, Ahmad A. Tarhini, Devin B. Lowe, Fei Ding, Amy Rose, Pawel Kalinski
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Journal for immunotherapy of cancer, vol 9, iss 11
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Journal for immunotherapy of cancer, vol 9, iss 11
BackgroundA first-in-human, randomized pilot phase II clinical trial combining vaccines targeting overexpressed, non-mutated tumor blood vessel antigens (TBVA) and tyrosine kinase inhibitor dasatinib was conducted in human leukocyte antigen (HLA)-A2+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f64e2b33170ed2494c9b7122765e2cf
https://pubmed.ncbi.nlm.nih.gov/34782430
https://pubmed.ncbi.nlm.nih.gov/34782430
Publikováno v:
Cancers
Cancers, Vol 13, Iss 2695, p 2695 (2021)
Cancers, Vol 13, Iss 2695, p 2695 (2021)
Simple Summary Immunotherapies have revolutionized the field of cancer therapeutics, yet a substantial subset of patients fail to respond. Recent efforts have focused on identifying targets that could elicit or augment anti-tumor immune responses. On
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e3b284ed71173fe6900ac7a08f18d1d
https://pubmed.ncbi.nlm.nih.gov/34070756
https://pubmed.ncbi.nlm.nih.gov/34070756
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Tertiary lymphoid structures (TLS) are non-encapsulated immune cell aggregates that form at sites of chronic inflammation, including in and around tumors. Recent studies have shown that the presence of TLS in human tumors is an indicator o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73d4119b147370adb6d24b91cf793758
https://doi.org/10.1136/jitc-2020-sitc2020.0584
https://doi.org/10.1136/jitc-2020-sitc2020.0584
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 26(17)
The cancer mutanome has been associated with disease prognosis as well as response to interventional immunotherapy and provides a substrate for development of personalized vaccines targeting tumor neoepitopes. Recent findings suggest that neoantigen-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39e49a675aeab5ccc13a366e0d57bbc8
https://pubmed.ncbi.nlm.nih.gov/32439700
https://pubmed.ncbi.nlm.nih.gov/32439700
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundTertiary lymphoid structures (TLS) are non-encapsulated immune cell aggregates that form at sites of chronic inflammation. Recent studies have shown that the presence of TLS in human tumors predicts extended survival and superior response t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed9b3a3fbf1205a6f64326f5b9930b58
https://doi.org/10.1136/jitc-2021-sitc2021.762
https://doi.org/10.1136/jitc-2021-sitc2021.762