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pro vyhledávání: '"Jessica N. Anderson"'
Publikováno v:
Multiple Sclerosis International, Vol 2023 (2023)
Gait speed is frequently the primary efficacy endpoint in clinical trials of interventions targeting mobility in people with multiple sclerosis (MS). However, it is unclear whether increased gait speed is a meaningful outcome for people living with M
Externí odkaz:
https://doaj.org/article/5e7b49c6111a4a779b8873510d76ba5b
Autor:
Dirk Iwata-Reuyl, Valérie de Crécy-Lagard, Shilah A. Bonnett, Jessica N. Anderson, Manal A. Swairjo, Basma El Yacoubi
Publikováno v:
Journal of Biological Chemistry. 281:37586-37593
GTP cyclohydrolase I (GCYH-I) is the first enzyme of the de novo tetrahydrofolate biosynthetic pathway present in bacteria, fungi, and plants, and encoded in Escherichia coli by the folE gene. It is also the first enzyme of the biopterin (BH4) pathwa
Publikováno v:
Blood. 106:2623-2623
p53 not only functions as a transcription factor but also has a direct extranuclear apoptogenic role at the mitochondria. We have discovered that DNA damage-induced p53/Bcl2 binding is associated with decreased Bcl2/Bax interaction and increased apop