Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jessica N, Mazerik"'
Publikováno v:
Cell Medicine
Across scientific disciplines, 3-D organoid culture systems offer platforms to integrate basic research findings with clinical care. The National Eye Institute mounted a $1.1 million 3-D Retina Organoid Challenge. Organoids developed through the Chal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21a865649483ba7b515e2ff6d1d927ef
https://escholarship.org/uc/item/58x7g4wf
https://escholarship.org/uc/item/58x7g4wf
Autor:
Bulent Arman Aksoy, Kenneth C. Smith, Stuart L. Schreiber, Zhou Ji, Olga Nikolova, Leandro C. Hermida, Daniela S. Gerhard, Aris Floratos, Vlado Dančík, Nadia L. Jaber, Jessica N. Mazerik, Paul A. Clemons, Benjamin Gross, Subhashini Jagu, Chris Sander, Andrea Califano
Publikováno v:
Database: The Journal of Biological Databases and Curation
The Cancer Target Discovery and Development (CTD2) Network aims to use functional genomics to accelerate the translation of high-throughput and high-content genomic and small-molecule data towards use in precision oncology. As part of this goal, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208ec0f9cc0a9646f281d6d68491d591
https://doi.org/10.1093/database/bax054
https://doi.org/10.1093/database/bax054
Autor:
Edus H. Warren, Anna Lasorella, Hanlee P. Ji, Alykhan F. Shamji, Michael A. White, Tina Zheng, Jonathan S. Weissman, Jesse S. Boehm, Stanley R. Riddell, Michael T. McManus, Chris Sander, Adam A. Margolin, Christopher J. Kemp, Haian Fu, Michael Boettcher, Stuart L. Schreiber, Ken Chen, Justin Chen, Frank McCormick, Andrea Califano, Raffaella Sordella, Calvin J. Kuo, Fadlo R. Khuri, Olivier Gevaert, Brent R. Stockwell, Paul A. Clemons, Scott Powers, Francisca Vazquez, Bridget K. Wagner, Barbara A. Weir, Cindy S. Hon, Sourav Bandyopadhyay, Harshil Dhruv, John D. Minna, John B. MacMillan, Darren Finlay, Carla Grandori, Jessica N. Mazerik, Michael G. Roth, Allan Balmain, Trever G. Bivona, Erin F. Simonds, Olga Nikolova, Zhenyi An, Daniela S. Gerhard, Margaret A. Johns, Ozlem Aksoy, Jose M. Silva, Bruce A. Posner, Kristiina Vuori, Subhashini Jagu, Eduardo Mendez, Seungchan Kim, Matthew J. Hangauer, Kenneth L. Scott, Jeff Kiefer, Gordon B. Mills, Martin W. McIntosh, William A. Weiss, Carlos S. Moreno, Michael E. Berens, Vijayakrishna K. Gadi, Scott W. Lowe, Han Liang, Mahalaxmi Aburi, Kenneth C. Smith, William C. Hahn, Alexander Krasnitz, Antonio Iavarone
The Cancer Target Discovery and Development (CTD2) Network was established to accelerate the transformation of “Big Data” into novel pharmacologic targets, lead compounds, and biomarkers for rapid translation into improved patient outcomes. It ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b6a618e692751cca99fccb4318e7924
https://europepmc.org/articles/PMC4987219/
https://europepmc.org/articles/PMC4987219/
Autor:
Jessica N. Mazerik, Matthew J. Tyska, Elizabeth A. Feeser, E. Michael Ostap, Serapion Pyrpassopoulos
Publikováno v:
Current Biology. 22(18):1688-1692
SummaryClass I myosins are molecular motors that link cellular membranes to the actin cytoskeleton and play roles in membrane tension generation, membrane dynamics, and mechanosignal transduction [1]. The widely expressed myosin-Ic (myo1c) isoform bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::617eff3916abbfebb2c0b2b57fc20ee0
Autor:
Jessica N. Mazerik, Matthew J. Tyska
Publikováno v:
Journal of Biological Chemistry. 287:13104-13115
One of the most abundant components of the enterocyte brush border is the actin-based monomeric motor, myosin-1a (Myo1a). Within brush border microvilli, Myo1a carries out a number of critical functions at the interface between membrane and actin cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f90b0d3931684d485ddcfac4259422e
https://doi.org/10.1074/jbc.m111.336313
https://doi.org/10.1074/jbc.m111.336313
Autor:
Periannan Kuppusamy, Ulysses J. Magalang, Sampath Parthasarathy, Elizabeth Susan O’Connor Butler, Narasimham L. Parinandi, Jessica N. Mazerik, Clay B. Marsh, Chandan K. Sen, Shariq I. Sherwani, Valorie Ciapala, Jason P. Cruff, Emily Steinhour
Publikováno v:
Molecular and Cellular Biochemistry. 315:97-112
We have earlier reported that the redox-active antioxidant, vitamin C (ascorbic acid), activates the lipid signaling enzyme, phospholipase D (PLD), at pharmacological doses (mM) in the bovine lung microvascular endothelial cells (BLMVECs). However, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa0b20e98388d8959b09ead5f079bc30
https://doi.org/10.1007/s11010-008-9793-6
https://doi.org/10.1007/s11010-008-9793-6
Autor:
Jessica N. Mazerik, Clay B. Marsh, Periannan Kuppusamy, Vivek A. Kuppusamy, Narasimham L. Parinandi, Emily Steinhour, Alon Peltz, Himabindu Mikkilineni
Publikováno v:
Toxicology Mechanisms and Methods. 17:541-557
Currently, mercury has been identified as a risk factor in cardiovascular diseases among humans. Here, we tested our hypothesis that mercury modulates the activity of the vascular endothelial cell (EC) lipid signaling enzyme phospholipase A(2) (PLA(2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b2a25cec04dc12dfa7b6fcf00c14da
https://doi.org/10.1080/15376510701380505
https://doi.org/10.1080/15376510701380505
Publikováno v:
Biophysical journal. 106(3)
Class 1 myosins are monomeric motor proteins that fulfill diverse functions at the membrane/cytoskeletal interface. All myosins-1 contain a motor domain, which binds actin, hydrolyzes ATP, and generates forces, and a TH1 domain, which interacts direc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e8120b0d59bf53048cea5c37fb5b4b
https://pubmed.ncbi.nlm.nih.gov/24507605
https://pubmed.ncbi.nlm.nih.gov/24507605
Autor:
Daniela S. Gerhard, Nadia L. Jaber, Martin L. Ferguson, Jaime M. Guidry Auvil, Jessica N. Mazerik, Nicholas B. Griner, Subhashini Jagu
Publikováno v:
Cancer Research. 76:5293-5293
The Office of Cancer Genomics (OCG), within the National Cancer Institute, supports cutting-edge genomics and translational research to advance the molecular understanding of cancer, with the ultimate goal of improving clinical outcomes through preci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67407bce0f6ea4428da43a25a561819c
https://doi.org/10.1158/1538-7445.am2016-5293
https://doi.org/10.1158/1538-7445.am2016-5293
Autor:
E Susan, O'Connor Butler, Jessica N, Mazerik, Jason P, Cruff, Shariq I, Sherwani, Barbara K, Weis, Clay B, Marsh, Achuthan C, Raghavamenon, Rao M, Uppu, Harald H O, Schmid, Narasimham L, Parinandi
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 610
The importance of understanding the mechanisms of modulation of cellular signaling cascades by the peroxidized membrane phospholipids (PLs) is well recognized. The enzyme-catalyzed peroxidation of PLs, as opposed to their oxidation by air and metal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf4a0d8b41a79489733fed9e15e0af07
https://pubmed.ncbi.nlm.nih.gov/20013191
https://pubmed.ncbi.nlm.nih.gov/20013191