Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jessica M. Ponce"'
Autor:
Jessica M. Ponce, Grace Coen, Kathryn M. Spitler, Nikola Dragisic, Ines Martins, Antentor Hinton, Margaret Mungai, Satya Murthy Tadinada, Hao Zhang, Gavin Y. Oudit, Long‐Sheng Song, Na Li, Peter Sicinski, Stefan Strack, E. Dale Abel, Colleen Mitchell, Duane D. Hall, Chad E. Grueter
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 7 (2020)
Background Nuclear‐to‐mitochondrial communication regulating gene expression and mitochondrial function is a critical process following cardiac ischemic injury. In this study, we determined that cyclin C, a component of the Mediator complex, regu
Externí odkaz:
https://doaj.org/article/25e15a470a0d4ce8a662239933b791ad
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 6 (2016)
Externí odkaz:
https://doaj.org/article/f71ec23774714ae8b82bb8ec96ffacc0
Autor:
George Dialynas, Om K Shrestha, Jessica M Ponce, Monika Zwerger, Dylan A Thiemann, Grant H Young, Steven A Moore, Liping Yu, Jan Lammerding, Lori L Wallrath
Publikováno v:
PLoS Genetics, Vol 11, Iss 5, p e1005231 (2015)
Mutations in the human LMNA gene cause muscular dystrophy by mechanisms that are incompletely understood. The LMNA gene encodes A-type lamins, intermediate filaments that form a network underlying the inner nuclear membrane, providing structural supp
Externí odkaz:
https://doaj.org/article/4c60fc51ebc44279a70fea6f7284eab9
Autor:
Kathryn M. Spitler, Na Li, Stefan Strack, Margaret Mungai, Ines Martins, Chad E. Grueter, E. Dale Abel, Grace Coen, Nikola Dragisic, Jessica M. Ponce, Antentor Othrell Hinton, Long-Sheng Song, Peter Sicinski, Duane D. Hall, Gavin Y. Oudit, Satya Murthy Tadinada, Colleen C. Mitchell, Hao Zhang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Nuclear‐to‐mitochondrial communication regulating gene expression and mitochondrial function is a critical process following cardiac ischemic injury. In this study, we determined that cyclin C, a component of the Mediator complex, regu
Autor:
Quan J. Zhang, Matthew Larson Murry, Chad E. Grueter, Matthew Harris, Jordan D. Fuqua, Cole T. Cochran, Sean Alexander, Dale Abel, Ana Kronemberger, Ranan Fattal, Jessica M. Ponce, Vitor A. Lira, Tyler Harper
Publikováno v:
The FASEB Journal. 34:1-1
Autor:
Biyi Chen, Kathryn M. Spitler, Long-Sheng Song, Adrianne Alexia, Duane D. Hall, Gavin Y. Oudit, Jessica M. Ponce, Chad E. Grueter
Publikováno v:
JCI Insight. 2
Widespread changes in cardiac gene expression occur during heart failure, yet the mechanisms responsible for coordinating these changes remain poorly understood. The Mediator complex represents a nodal point for modulating transcription by bridging c
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 312(4)
The mediator complex, a multisubunit nuclear complex, plays an integral role in regulating gene expression by acting as a bridge between transcription factors and RNA polymerase II. Genetic deletion of mediator subunit 1 (Med1) results in embryonic l
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
In the United States alone, 1 person dies from a coronary event approximately every 1.5 minutes.[1][1] Cardiovascular disease (CVD) encompasses larger subclasses of diseases, such as hypertension, coronary/peripheral artery disease, endothelial dysfu
Publikováno v:
Circulation Research. 117
Alterations in gene transcription are commonly associated with cardiovascular disease pathogenesis characterized by cardiomyocyte hypertrophy. The phenotypic responses result in diminished cardiac contractility, ventricular dilation, fibrosis and ult
Autor:
Monika Zwerger, George Dialynas, Grant H. Young, Liping Yu, Jessica M. Ponce, Lori L. Wallrath, Steven A. Moore, Dylan A. Thiemann, Om K. Shrestha, Jan Lammerding
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 11, Iss 5, p e1005231 (2015)
PLoS Genetics, Vol 11, Iss 5, p e1005231 (2015)
Mutations in the human LMNA gene cause muscular dystrophy by mechanisms that are incompletely understood. The LMNA gene encodes A-type lamins, intermediate filaments that form a network underlying the inner nuclear membrane, providing structural supp