Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Jessica M. J. Swanson"'
Publikováno v:
Toxins, Vol 15, Iss 8, p 486 (2023)
Mycolactone is an exotoxin produced by Mycobacterium ulcerans that causes the neglected tropical skin disease Buruli ulcer. This toxin inhibits the Sec61 translocon in the endoplasmic reticulum (ER), preventing the host cell from producing several se
Externí odkaz:
https://doaj.org/article/10d4da25abf74954a193e0545b81f5eb
Autor:
R. Jay Braun, Jessica M. J. Swanson
Publikováno v:
Membranes, Vol 12, Iss 10, p 949 (2022)
Lipid droplets are essential organelles that store and traffic neutral lipids. The phospholipid monolayer surrounding their neutral lipid core engages with a highly dynamic proteome that changes according to cellular and metabolic conditions. Recent
Externí odkaz:
https://doaj.org/article/99c7446d1a364afdb7a33c2d55e34143
Publikováno v:
bioRxiv
Mycolactone is an exotoxin produced byMycobacterium ulceransthat causes the neglected tropical skin disease Buruli ulcer. This toxin inhibits the Sec61 translocon in the endoplasmic reticulum (ER), preventing the host cell from producing many secreto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd3e12a5365e391e9f9422777706f126
https://europepmc.org/articles/PMC10245786/
https://europepmc.org/articles/PMC10245786/
Publikováno v:
The journal of physical chemistry. B. 126(11)
Lipid droplets (LDs) are intracellular organelles whose primary function is energy storage. Known to emerge from the endoplasmic reticulum (ER) bilayer, LDs have a unique structure with a core consisting of neutral lipids, triacylglycerol (TG) or ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b90cd2a5df9b6e3125e3d1751f08783
https://pubmed.ncbi.nlm.nih.gov/35263109
https://pubmed.ncbi.nlm.nih.gov/35263109
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 2, p e1005972 (2018)
Mycolactone is the exotoxin produced by Mycobacterium ulcerans and is the virulence factor behind the neglected tropical disease Buruli ulcer. The toxin has a broad spectrum of biological effects within the host organism, stemming from its interactio
Externí odkaz:
https://doaj.org/article/9343a1d15f8e4a7a897ba8afa8e2e86f
Publikováno v:
J Phys Chem B
Canonical descriptions of multistep biomolecular transformations generally follow a single-pathway viewpoint, with a series of transitions through intermediates converting reactants to products or repeating a conformational cycle. However, mounting e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e384f7eada380eccdfdf82145f90ce
https://doi.org/10.1021/acs.jpcb.1c03304
https://doi.org/10.1021/acs.jpcb.1c03304
Publikováno v:
J Phys Chem B
Lipid droplets (LDs) are intracellular storage organelles composed of neutral lipids, such as triacylglycerol (TG), surrounded by a phospholipid (PL) monolayer decorated with specific proteins. Herein, we investigate the mechanism of protein associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6edb2c9bf7d05edb64d64cbaa61ce47
https://doi.org/10.1021/acs.jpcb.1c01795
https://doi.org/10.1021/acs.jpcb.1c01795
Publikováno v:
Biophysical journal. 121(22)
Mycolactone is a cytotoxic and immunosuppressive macrolide produced by Mycobacterium ulcerans and the sole causative agent of the neglected tropical skin disease Buruli ulcer. The toxin acts by invading host cells and interacting with intracellular t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e311b3bd66599c438ec7c9cf559a4d7d
https://pubmed.ncbi.nlm.nih.gov/36258678
https://pubmed.ncbi.nlm.nih.gov/36258678
Autor:
Siyoung Kim, Jessica M. J. Swanson
Publikováno v:
Biophys J
Lipid droplets (LDs) are energy storage organelles composed of neutral lipids, such as triacylglycerol (TG) and sterol esters, surrounded by a phospholipid (PL) monolayer. Their central role in metabolism, complex life cycle, and unique lipid monolay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b32c8190aa3eda4ab5df0272e3d5b7
https://doi.org/10.1016/j.bpj.2020.10.001
https://doi.org/10.1016/j.bpj.2020.10.001
Autor:
Chenghan Li, Jessica M. J. Swanson
Publikováno v:
J Phys Chem B
Proton transport in aqueous media is ubiquitously important in chemical and biological processes. Although ab initio molecular dynamics (AIMD) simulations have made great progress in characterizing proton transport, there has been a long-standing cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f747f6f78e30998232e5c431f1b1619
https://doi.org/10.1021/acs.jpcb.0c03615
https://doi.org/10.1021/acs.jpcb.0c03615