Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jessica M. Halow"'
Autor:
Jessica M. Halow, Rachel Byron, Megan S. Hogan, Raquel Ordoñez, Mark Groudine, M. A. Bender, John A. Stamatoyannopoulos, Matthew T. Maurano
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The functional consequences of variation in human regulatory DNA depend on the local chromatin environment and the cell/tissue context. Here the authors use highly diverged hybrid mice to study genetic effects on DNA accessibility in vivo across mult
Externí odkaz:
https://doaj.org/article/1d484e6b9c4d452395c7af6a519b4e6c
Thermodynamic limitation for Ca2+handling contributes to decreased contractile reserve in rat hearts
Autor:
Markus Meyer, Jessica M. Halow, Vincent M. Figueredo, Joanne S. Ingwall, Rong Tian, Wolfgang H. Dillmann, S. Albert Camacho
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 275:H2064-H2071
The free energy release from ATP hydrolysis (‖ΔG∼p‖) is decreased by inhibiting the creatine kinase (CK) reaction, which may limit the thermodynamic driving force for the sarcoplasmic reticulum (SR) Ca2+pumps and thereby cause a decrease in co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d7bf8a65806492a1cdc01f922eea4ea
https://doi.org/10.1152/ajpheart.1998.275.6.h2064
https://doi.org/10.1152/ajpheart.1998.275.6.h2064
Publikováno v:
Journal of molecular and cellular cardiology. 31(9)
The goal of this study was to test the hypothesis that during myocardial ischemia, slowing of the Ca(2+) transient decline causes slowed relaxation. Our approach was to monitor pressure and Ca(2+) transients in isovolumic rat hearts during control an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf1c5a031de08a5e778baa5da7a53bf
https://pubmed.ncbi.nlm.nih.gov/10471357
https://pubmed.ncbi.nlm.nih.gov/10471357
Autor:
Matthias Spindler, James C.A. Hopkins, S. A. Camacho, Rong Tian, Jessica M. Halow, Michael E. Christe, Joanne S. Ingwall
Publikováno v:
The Journal of clinical investigation. 99(4)
Sarcomere relaxation depends on dissociation of actin and myosin, which is regulated by a number of factors, including intracellular [MgATP] as well as MgATP hydrolysis products [MgADP] and inorganic phosphate [Pi], pHi, and cytosolic calcium concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ecd8512a1123160d2fb6f69064b8dcd
https://pubmed.ncbi.nlm.nih.gov/9045879
https://pubmed.ncbi.nlm.nih.gov/9045879
There is no consensus for a detailed model of the regulation of mitochondrial ATP production in cells. The problem of metabolic control in intact tissues is extremely difficult for two reasons. First, it is not clear how best to measure the parameter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::510df3bab79016ecc71558e5930ad324
https://doi.org/10.1016/s1569-2558(08)60253-2
https://doi.org/10.1016/s1569-2558(08)60253-2
Phosphocreatine protects transgenic mouse liver expressing creatine kinase from hypoxia and ischemia
Publikováno v:
The American journal of physiology. 265(6 Pt 1)
Creatine kinase (CK) is normally found at high levels in muscle and brain and catalyzes the reaction phosphocreatine (PCr) + MgADP + H+creatine (Cr) + MgATP. CK is not normally found at high levels in liver. A line of transgenic mice that express hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f61a664fbcbe424b0261ef99ffed60f
https://pubmed.ncbi.nlm.nih.gov/8279516
https://pubmed.ncbi.nlm.nih.gov/8279516