Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jessica M. Hair"'
Autor:
Charles W. Loftin, Alexandros G. Georgakilas, Khaled Aziz, Olga A. Sedelnikova, Dave C. Francisco, Jessica M. Hair, Thomas A. Winters, Prakash Peddi, Jennifer S. Dickey, Kara J. Burns, Mihalis I. Panayiotidis, William M. Bonner
Publikováno v:
Free Radical Biology and Medicine. 48:1435-1443
DNA-dependent protein kinase (DNA-PK) is a key non-homologous end joining (NHEJ) nuclear serine/threonine protein kinase involved in various DNA metabolic and damage signaling pathways contributing to the maintenance of genomic stability and preventi
Autor:
Dave C. Francisco, Mihalis I. Panayiotidis, Jessica M. Hair, Alexandros G. Georgakilas, Prakash Peddi, Angela M. Cecil
Publikováno v:
Cancer Letters. 269:174-183
Complex DNA damage such as double strand breaks (DSBs) and non-DSB bistranded oxidative clustered DNA lesions (OCDL) (two or more DNA lesions within a short DNA fragment of 1-10bp on opposing DNA strands) are considered the hallmark of ionizing radia
Publikováno v:
Current Protocols in Cell Biology
The two basic groups of complex DNA damage are double-strand breaks (DSBs) and non-DSB oxidatively-induced clustered DNA lesions (OCDLs). The single-cell gel electrophoresis (SCGE) or comet assay has been widely used for the detection of low levels o
Autor:
Katie A. Lehockey, Georgia I. Terzoudi, Devika Srivastava, Gabriel E. Pantelias, Jessica M. Hair, Vasiliki I. Hatzi, Alexandros G. Georgakilas, Weixin Wang
Publikováno v:
Chemico-biological interactions. 188(2)
Oxidatively-induced clustered DNA lesions are considered the signature of any ionizing radiation like the ones human beings are exposed daily from various environmental sources (medical X-rays, radon, etc.). To evaluate the role of BRCA1 deficiencies
Autor:
Brittany A. Flood, Dave C. Francisco, Jessica M. Hair, Prakash Peddi, Peter T. Kalogerinis, Angela M. Cecil, George Sigounas, Alexandros G. Georgakilas
Publikováno v:
Free radical biologymedicine. 44(4)
Oxidatively induced stress and DNA damage have been associated with various human pathophysiological conditions, including cancer and aging. Complex DNA damage such as double-strand breaks (DSBs) and non-DSB bistranded oxidatively induced clustered D