Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jessica M. Gomes"'
Autor:
Gurdyal S. Besra, Sharon L. Kendall, Yi Zhang, Kim A. Hatch, Philip Marsh, Neil G. Stoker, Lorenz Wernisch, Jessica M. Gomes, Joanna Bacon, Philip D. Butcher, Lynn G. Dover
Publikováno v:
Microbiology. 153:1435-1444
The low level of available iron in vivo is a major obstacle for microbial pathogens and is a stimulus for the expression of virulence genes. In this study, Mycobacterium tuberculosis H37Rv was grown aerobically in the presence of limited iron availab
Autor:
Monica Singh, Geoffrey W. de Lisle, Desmond M. Collins, Grant S. Hotter, Gurdyal S. Besra, Pania Mouat, Shalome A. Bassett, B.J. Wards, Jessica M. Gomes, Pamela Kawakami, Paul R. Wheeler
Publikováno v:
Journal of Bacteriology. 187:2267-2277
The unusual and complex cell wall of pathogenic mycobacteria plays a major role in pathogenesis, with specific complex lipids acting as defensive, offensive, or adaptive effectors of virulence. The phthiocerol and phthiodiolone dimycocerosate esters
Autor:
Frank Follmann, Jessica M. Gomes, Else Marie Agger, Gurdyal S. Besra, Roland Lang, Ida Rosenkrands, Dennis Christensen, Claire Swetman Andersen, Carsten J. Kirschning, David E. Minnikin, Pernille Nordly, Peter Andersen, Anja Olsen, Veemal Bhowruth
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 183(4)
The immunostimulatory activity of lipids associated with the mycobacterial cell wall has been recognized for several decades and exploited in a large variety of different adjuvant preparations. Previously, we have shown that a mycobacterial lipid ext
EthA, a common activator of thiocarbamide-containing drugs acting on different mycobacterial targets
Autor:
Robert C. Reynolds, Laurent Kremer, Paul Gratraud, Gurdyal S. Besra, Anuradha Alahari, Lynn G. Dover, Jessica M. Gomes, Veemal Bhowruth
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2007, 51 (3), pp.1055-63. ⟨10.1128/AAC.01063-06⟩
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2007, 51 (3), pp.1055-63. ⟨10.1128/AAC.01063-06⟩
Many of the current antimycobacterial agents require some form of cellular activation unmasking reactive groups, which in turn will bind to their specific targets. Therefore, understanding the mechanisms of activation of current antimycobacterials no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f15bbaa1374d6040ae4adc43d71e99
https://hal.archives-ouvertes.fr/hal-00150519
https://hal.archives-ouvertes.fr/hal-00150519