Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jessica M. Collins"'
Autor:
Jane Alty, Lynette R. Goldberg, Eddy Roccati, Katherine Lawler, Quan Bai, Guan Huang, Aidan D Bindoff, Renjie Li, Xinyi Wang, Rebecca J. St George, Kaylee Rudd, Larissa Bartlett, Jessica M. Collins, Mimieveshiofuo Aiyede, Nadeeshani Fernando, Anju Bhagwat, Julia Giffard, Katharine Salmon, Scott McDonald, Anna E. King, James C. Vickers
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Dementia prevalence is predicted to triple to 152 million globally by 2050. Alzheimer’s disease (AD) constitutes 70% of cases. There is an urgent need to identify individuals with preclinical AD, a 10–20-year period of progres
Externí odkaz:
https://doaj.org/article/74f6fbaa4eec4ff48e00b119eaf2c298
Autor:
Andrew J. Phipps, Samuel Dwyer, Jessica M. Collins, Fariha Kabir, Rachel AK. Atkinson, Md Anisuzzaman Chowdhury, Lyzette Matthews, Deepika Dixit, Rhiannon S. Terry, Jason Smith, Nuri Gueven, William Bennett, Anthony L. Cook, Anna E. King, Sharn Perry
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34587- (2024)
The loss of upper and lower motor neurons, and their axons is central to the loss of motor function and death in amyotrophic lateral sclerosis (ALS). Due to the diverse range of genetic and environmental factors that contribute to the pathogenesis of
Externí odkaz:
https://doaj.org/article/7531f8291b514223ba86fbf01962189c
Does serum neurofilament light help predict accelerated cognitive ageing in unimpaired older adults?
Autor:
Jessica M. Collins, Aidan D. Bindoff, Eddy Roccati, Jane E. Alty, James C. Vickers, Anna E. King
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionNeurofilament light (NfL) is a blood biomarker of neurodegeneration. While serum NfL levels have been demonstrated to increase with normal ageing, the relationship between serum NfL levels and normal age-related changes in cognitive funct
Externí odkaz:
https://doaj.org/article/23b3e954c4794582b21d8c76f84a5a5e
Autor:
Jane Alty, Quan Bai, Renjie Li, Katherine Lawler, Rebecca J. St George, Edward Hill, Aidan Bindoff, Saurabh Garg, Xinyi Wang, Guan Huang, Kaining Zhang, Kaylee D. Rudd, Larissa Bartlett, Lynette R. Goldberg, Jessica M. Collins, Mark R. Hinder, Sharon L. Naismith, David C. Hogg, Anna E. King, James C. Vickers
Publikováno v:
BMC Neurology, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background The worldwide prevalence of dementia is rapidly rising. Alzheimer’s disease (AD), accounts for 70% of cases and has a 10–20-year preclinical period, when brain pathology covertly progresses before cognitive symptoms appear. Th
Externí odkaz:
https://doaj.org/article/480ea2a8937f452e859aaf3451cc9168
Autor:
Jessica M. Collins, Rachel A.K. Atkinson, Lyzette M. Matthews, Isabella C. Murray, Sharn E. Perry, Anna E. King
Publikováno v:
Neurobiology of Disease, Vol 172, Iss , Pp 105821- (2022)
The mechanisms underlying the loss of motor neuron axon integrity in amyotrophic lateral sclerosis (ALS) are unclear. SARM1 has been identified as a genetic risk variant in sporadic ALS, and the SARM1 protein is a key mediator of axon degeneration. T
Externí odkaz:
https://doaj.org/article/aee574e35db0403b9102ac2971707900
Autor:
Jessica M. Collins, Edward Hill, Aidan Bindoff, Anna E. King, Jane Alty, Mathew J. Summers, James C. Vickers
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Background: The brain-derived neurotrophic factor (BDNF) protein has been shown to have a prominent role in neuron survival, growth, and function in experimental models, and the BDNF Val66Met polymorphism which regulates its expression has been linke
Externí odkaz:
https://doaj.org/article/acd8f355224d4569b7db96ed550991e9
Autor:
Desiree M. Markantone, Atif Towheed, Aaron T. Crain, Jessica M. Collins, Alicia M. Celotto, Michael J. Palladino
Publikováno v:
Neurobiology of Disease, Vol 117, Iss , Pp 203-210 (2018)
Mitochondrial encephalomyopathies (MEs) result from mutations in mitochondrial genes critical to oxidative phosphorylation. Severe and untreatable ME results from mutations affecting each endogenous mitochondrial encoded gene, including all 13 establ
Externí odkaz:
https://doaj.org/article/1d7b2d5169c747a2b77b765c85e314f5
Autor:
Gary P. Morris, Catherine G. Foster, Jo‐Maree Courtney, Jessica M. Collins, Jake M. Cashion, Lachlan S. Brown, David W. Howells, Gabriele C. DeLuca, Alison J. Canty, Anna E. King, Jenna M. Ziebell, Brad A. Sutherland
Publikováno v:
Glia.
Autor:
Michael I. Garry, Ross C. Langley, Jeffery J. Summers, Aidan Bindoff, Alexander D. Tang, Mark R. Hinder, William Bennett, Samuel J. Bolland, Alison J. Canty, Jessica M Collins, Jennifer Rodger
Publikováno v:
Brain Stimulation, Vol 14, Iss 6, Pp 1498-1507 (2021)
BackgroundRepetitive transcranial magnetic stimulation (rTMS) is a non-invasive tool commonly used to drive neural plasticity in the young adult and aged brain. Recent data from mouse models have shown that even at subthreshold intensities (0.12 Tesl
Publikováno v:
Brain Structure and Function. 226:2041-2055
The calcium binding protein parvalbumin is expressed in interneurons of two main morphologies, the basket and chandelier cells, which target perisomatic domains on principal cells and are extensively interconnected in laminar networks by synapses and