Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Jessica L. Whited"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Throughout the animal kingdom regenerative ability varies greatly from species to species, and even tissue to tissue within the same organism. The sheer diversity of structures and mechanisms renders a thorough comparison of molecular processes truly
Externí odkaz:
https://doaj.org/article/f092071353214a0ebfc191dd1394c0e4
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-11 (2021)
Abstract Regeneration is an elegant and complex process informed by both local and long-range signals. Many current studies on regeneration are largely limited to investigations of local modulators within a canonical cohort of model organisms. Enhanc
Externí odkaz:
https://doaj.org/article/f6c31968a81740f6ad9728b555614f8d
Autor:
Fallon Durant, Jessica L. Whited
Publikováno v:
Advanced Science, Vol 8, Iss 15, Pp n/a-n/a (2021)
Abstract Soft tissue fibrosis and cutaneous scarring represent massive clinical burdens to millions of patients per year and the therapeutic options available are currently quite limited. Despite what is known about the process of fibrosis in mammals
Externí odkaz:
https://doaj.org/article/93bda38fcf5c453cb30474819430d43c
Publikováno v:
EvoDevo, Vol 10, Iss 1, Pp 1-13 (2019)
Abstract Complete and perfect regeneration of appendages is a process that has fascinated and perplexed biologists for centuries. Some tetrapods possess amazing regenerative abilities, but the regenerative abilities of others are exceedingly limited.
Externí odkaz:
https://doaj.org/article/c4fb385d32f04370ba25d56be32b1327
Autor:
Nicholas D. Leigh, Garrett S. Dunlap, Kimberly Johnson, Rachelle Mariano, Rachel Oshiro, Alan Y. Wong, Donald M. Bryant, Bess M. Miller, Alex Ratner, Andy Chen, William W. Ye, Brian J. Haas, Jessica L. Whited
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Limb regeneration requires a blastema with progenitor cells, immune cells, and an overlying wound epidermis, but molecular identities of these populations are unclear. Here, the authors use single-cell RNA-sequencing to identify transcriptionally dis
Externí odkaz:
https://doaj.org/article/4ed4afd9e0f24ba282c5975966235607
Autor:
Donald M. Bryant, Kimberly Johnson, Tia DiTommaso, Timothy Tickle, Matthew Brian Couger, Duygu Payzin-Dogru, Tae J. Lee, Nicholas D. Leigh, Tzu-Hsing Kuo, Francis G. Davis, Joel Bateman, Sevara Bryant, Anna R. Guzikowski, Stephanie L. Tsai, Steven Coyne, William W. Ye, Robert M. Freeman Jr., Leonid Peshkin, Clifford J. Tabin, Aviv Regev, Brian J. Haas, Jessica L. Whited
Publikováno v:
Cell Reports, Vol 18, Iss 3, Pp 762-776 (2017)
Mammals have extremely limited regenerative capabilities; however, axolotls are profoundly regenerative and can replace entire limbs. The mechanisms underlying limb regeneration remain poorly understood, partly because the enormous and incompletely s
Externí odkaz:
https://doaj.org/article/1952cf1abfac437ca3a57a2785b1e578
Autor:
Laura de Girolamo, Luiz Felipe Morlin Ambra, Carlotta Perucca Orfei, John P. McQuilling, Kelly A. Kimmerling, Katie C. Mowry, Kimberly A. Johnson, Amy T. Phan, Jessica L. Whited, Andreas H. Gomoll
Publikováno v:
Cells, Vol 8, Iss 11, p 1411 (2019)
Treatment of tendon injuries is challenging, with neither conservative nor surgical approaches providing full recovery. Placental-derived tissues represent a promising tool for the treatment of tendon injuries. In this study, human amniotic suspensio
Externí odkaz:
https://doaj.org/article/871feca15bd842aebff5e6211a772684
Publikováno v:
Methods in Molecular Biology ISBN: 9781071626580
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::791e0cbbfcb67f35c09f11c1ff4be0c0
https://doi.org/10.1007/978-1-0716-2659-7_22
https://doi.org/10.1007/978-1-0716-2659-7_22
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2562
Clustered regularly interspaced short palindromic repeats (CRISPR) is a powerful tool that enables editing of the axolotl genome. In this chapter, we will cover how to retrieve gene sequences, confirm annotation, design CRISPR targets, analyze indels
Publikováno v:
Developmental Dynamics. 250:750-752