Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Jessica L. Rouge"'
Autor:
Ina F. de la Fuente, Shraddha S. Sawant, Mark Q. Tolentino, Patrick M. Corrigan, Jessica L. Rouge
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Therapeutic nucleic acids hold immense potential in combating undruggable, gene-based diseases owing to their high programmability and relative ease of synthesis. While the delivery of this class of therapeutics has successfully entered the clinical
Externí odkaz:
https://doaj.org/article/ddd4d3f7cb504ca0a9bf8c185f64f1e8
Autor:
Suman Pal, Ina F. de la Fuente, Shraddha S. Sawant, Jenna N. Cannata, Wu He, Jessica L. Rouge
Publikováno v:
Bioconjugate Chemistry.
Publikováno v:
ChemBioChem.
Autor:
Tyler D Gavitt, Jessica L. Rouge, Steven M. Szczepanek, Arlind B Mara, Alyssa K. Hartmann, Shraddha S. Sawant
Publikováno v:
ACS Nano. 15:11192-11201
Allergic asthma is one of the leading chronic lung diseases of both children and adults worldwide, resulting in significant morbidity and mortality in affected individuals. Many patients have severe asthma, which is refractory to treatment, illustrat
Autor:
Mark Q. Tolentino, Jessica L. Rouge
Publikováno v:
Materials Advances. 2:2267-2271
Herein we report a thermoresponsive crosslinker that can be utilized to stabilize the surface of micelles through a “click” reaction and to trigger the disassembly via a retro Diels Alder (rDA) mechanism. The micelles generated were 100 nm in siz
Multi-layered stimuli responsive DNA micelles for the stepwise controlled release of small molecules
Publikováno v:
Journal of materials chemistry. B. 10(37)
Controllable release of multiple distinct cargoes from a nanomaterial is crucial to a variety of therapeutic and catalytic applications. In this study, we describe a DNA functionalized multi-layered surface crosslinked micelle (mlSCM) consisting of i
Publikováno v:
Bioconjugate Chemistry. 31:1063-1069
Using a recently developed nucleic acid delivery platform, we demonstrate the effective delivery of metallodrug [AuIIIBr2(SSC-Inp-OEt)] (AP228; Inp = isonipecotic moiety), a hydrophobic, low solubility gold complex cytotoxic to cancer cells. It is sh
Publikováno v:
RSC Advances. 10:42349-42353
Intracellular trafficking and delivery of nucleic acids is an area of growing interest, particularly as it relates to therapeutic applications. Spectroscopic methods have been used to observe and quantitatively measure the delivery of oligonucleotide
Autor:
Soyoung E. Seo, Mary X. Wang, Chad M. Shade, Jessica L. Rouge, Keith A. Brown, Chad A. Mirkin
Publikováno v:
Spherical Nucleic Acids ISBN: 9780429200151
Spherical Nucleic Acids ISBN: 9781003056690
Spherical Nucleic Acids ISBN: 9781003056690
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13caa79bd0da4f04936bb71688f31c92
https://doi.org/10.4324/9780429200151-47
https://doi.org/10.4324/9780429200151-47