Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jessica L. Reinardy"'
Autor:
Jessica L Reinardy, Daniel M Corey, Christelle Golzio, Sarah B Mueller, Nicholas Katsanis, Christopher D Kontos
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139614 (2015)
The endothelial receptor tyrosine kinase (RTK) Tie1 was discovered over 20 years ago, yet its precise function and mode of action remain enigmatic. To shed light on Tie1's role in endothelial cell biology, we investigated a potential threonine phosph
Externí odkaz:
https://doaj.org/article/cf43434ad6a1446398e1f56412f48133
Autor:
Douglas A. Marchuk, Espen E. Spangenburg, Thomas D. Green, Sehoon Keum, Ayotunde O. Dokun, Joseph M. McClung, Christopher D. Kontos, Timothy J. McCord, Jessica L. Reinardy, Christopher D. Lascola, Brian H. Annex, Cameron A. Schmidt, Sarah B. Mueller, Terence E. Ryan, Talaignair N. Venkatraman, Kevin W. Southerland
Publikováno v:
Circulation. 136:281-296
Background: Critical limb ischemia is a manifestation of peripheral artery disease that carries significant mortality and morbidity risk in humans, although its genetic determinants remain largely unknown. We previously discovered 2 overlapping quant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::985e04abb07f79b0c4051fc53e0ea327
https://doi.org/10.1161/circulationaha.116.024873
https://doi.org/10.1161/circulationaha.116.024873
Publikováno v:
Neuroscience Letters. 451:124-128
Presenilin-1 is required for gamma-secretase activity, which participates in Notch receptor processing, the pathogenesis of Alzheimer's disease and the modulation of Ca(2+) signaling. We tested the hypothesis that gamma-secretase proteolytic activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa44ac6c21c04a1cabac59ae1293a36b
https://doi.org/10.1016/j.neulet.2008.12.031
https://doi.org/10.1016/j.neulet.2008.12.031
Autor:
David Brown, Terence E. Ryan, Sabah N. A. Hussain, Sarah B. Mueller, Christopher D. Kontos, Cameron A. Schmidt, Joseph M. McClung, Thomas D. Green, Jessica L. Reinardy, Timothy J. McCord
Publikováno v:
Frontiers in Physiology, Vol 6 (2015)
Frontiers in Physiology
Frontiers in Physiology
Recent strategies to treat peripheral arterial disease (PAD) have focused on stem cell based therapies, which are believed to result in local secretion of vascular growth factors. Little is known, however, about the role of ischemic endogenous cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a0fe1147b991d583fe31d4ed9cdfbb6
https://doi.org/10.3389/fphys.2015.00161
https://doi.org/10.3389/fphys.2015.00161
Autor:
Kun Ding, Raquel Lima e Silva, Christopher P. Seidel, Huiming Xia, Aling Dong, Jikui Shen, Dietmar Vestweber, Bonnie L. Lee, Joseph M. McClung, Maike Frye, Sean F. Hackett, Peter A. Campochiaro, Masashi Kojima, Brian W. Howard, Jessica L. Reinardy, Kevin G. Peters, Jiangxia Wang, Christopher D. Kontos
Retinal and choroidal neovascularization (NV) and vascular leakage contribute to visual impairment in several common ocular diseases. The angiopoietin/TIE2 (ANG/TIE2) pathway maintains vascular integrity, and negative regulators of this pathway are p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e515af0a2d6eea867a6619ff884377cb
https://europepmc.org/articles/PMC4191011/
https://europepmc.org/articles/PMC4191011/
