Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jessica L. Kelliher"'
Autor:
Jessica L. Kelliher, Melissa L. Folkerts, Kaiyuan V. Shen, Wan Song, Kyle Tengler, Clara M. Stiefel, Seong-Ok Lee, Eloise Dray, Weixing Zhao, Brian Koss, Nicholas R. Pannunzio, Justin W. Leung
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The master DNA damage repair histone protein, H2AX, is essential for orchestrating the recruitment of downstream mediator and effector proteins at damaged chromatin. The phosphorylation of H2AX at S139, γH2AX, is well-studied for its DNA re
Externí odkaz:
https://doaj.org/article/f40958dd8a9b496c9a1c7b226404941a
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Histone ubiquitination plays a critical role in the DNA damage response pathway. Here the authors reveal how RNF168 ubiquitinates the H2A family including noncanonical variants, H2AZ and macroH2A1/2, at the divergent N-terminal tail lysine residue.
Externí odkaz:
https://doaj.org/article/78f4cd1bfa81402db000d570e1f392c6
Autor:
Kyle P. Grim, Brian San Francisco, Jana N. Radin, Erin B. Brazel, Jessica L. Kelliher, Paola K. Párraga Solórzano, Philip C. Kim, Christopher A. McDevitt, Thomas E. Kehl-Fie
Publikováno v:
mBio, Vol 8, Iss 5 (2017)
ABSTRACT During infection, the host sequesters essential nutrients, such as zinc, to combat invading microbes. Despite the ability of the immune effector protein calprotectin to bind zinc with subpicomolar affinity, Staphylococcus aureus is able to s
Externí odkaz:
https://doaj.org/article/8a26e45d09634efa9423ab852119bcc0
Autor:
Analiz Rodriguez, Sydnye L Shuttleworth, Michael A Bauer, Jessica L Kelliher, Lora J Rogers, Daniel Fil, Brian Koss, Latambria Hampton, Emilie Darrigues
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/d28e0263cb6c43149ee8399116c4bb93
Autor:
Sydnye L Shuttleworth, Aaron J Storey, Michael A Bauer, Jessica L Kelliher, Lora J Rogers, Daniel Fil, Rick D Edmondson, Sam G Mackintosh, Alan J Tackett, Brian Koss
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/9cb38792be9547f0b106a607b70915a1
Autor:
Jana N Radin, Jessica L Kelliher, Paola K Párraga Solórzano, Kyle P Grim, Rouhallah Ramezanifard, James M Slauch, Thomas E Kehl-Fie
Publikováno v:
PLoS Pathogens, Vol 15, Iss 7, p e1007971 (2019)
The ability of Staphylococcus aureus and other pathogens to consume glucose is critical during infection. However, glucose consumption increases the cellular demand for manganese sensitizing S. aureus to host-imposed manganese starvation. The current
Externí odkaz:
https://doaj.org/article/7b023c0d80744da4b0ea9daddb491223
Publikováno v:
PLoS Pathogens, Vol 12, Iss 11, p e1006040 (2016)
During infection the host imposes manganese and zinc starvation on invading pathogens. Despite this, Staphylococcus aureus and other successful pathogens remain capable of causing devastating disease. However, how these invaders adapt to host-imposed
Externí odkaz:
https://doaj.org/article/b7047a69f1cf48c9a2f99135d8904540
Autor:
L. An, Robert L. Eoff, Michael S.Y. Huen, Jiadong Wang, Zhanzhan Xu, Jessica L. Kelliher, Justin W.C. Leung, Megan R. Reed, Kirk West
Publikováno v:
Nucleic Acids Research. 47:6236-6249
The tumor suppressor protein 53BP1 plays key roles in response to DNA double-strand breaks (DSBs) by serving as a master scaffold at the damaged chromatin. Current evidence indicates that 53BP1 assembles a cohort of DNA damage response (DDR) factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af01a8dfe68c765cbadf4fe0f10bd54
https://doi.org/10.1093/nar/gkz263
https://doi.org/10.1093/nar/gkz263
Publikováno v:
FEBS J
The chromatin-based DNA damage response pathway is tightly orchestrated by histone post-translational modifications, including histone H2A ubiquitination. Ubiquitination plays an integral role in regulating cellular processes including DNA damage sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::516334514b8e40cce6bf88178a423a38
https://europepmc.org/articles/PMC8486888/
https://europepmc.org/articles/PMC8486888/
Autor:
Kevin M. Grudzinski, Aleeza J. Leder Macek, Thomas E. Kehl-Fie, Jessica L. Kelliher, Jana N. Radin
Publikováno v:
J Bacteriol
Phosphate is an essential nutrient that Staphylococcus aureus and other pathogens must acquire from the host during infection. While inorganic monophosphate (Pi) is the preferred source of this nutrient, bacteria can also obtain it from phosphate-con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06cc7457bbb5a6e479d556b4aa2619db
https://europepmc.org/articles/PMC7585055/
https://europepmc.org/articles/PMC7585055/