Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jessica L. E. Hill"'
Autor:
Maikel L. Colli, Mireia Ramos-Rodríguez, Ernesto S. Nakayasu, Maria I. Alvelos, Miguel Lopes, Jessica L. E. Hill, Jean-Valery Turatsinze, Alexandra Coomans de Brachène, Mark A. Russell, Helena Raurell-Vila, Angela Castela, Jonàs Juan-Mateu, Bobbie-Jo M. Webb-Robertson, Lars Krogvold, Knut Dahl-Jorgensen, Lorella Marselli, Piero Marchetti, Sarah J. Richardson, Noel G. Morgan, Thomas O. Metz, Lorenzo Pasquali, Décio L. Eizirik
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
The cytokine IFNα is expressed in the islets of individuals with type 1 diabetes and contributes to local inflammation and destruction of beta cells. Here, the authors provide a global multiomics view of IFNα-induced changes in human beta cells at
Externí odkaz:
https://doaj.org/article/7ba57ffc94954c2897c0cf413d87e02a
Autor:
Sarah J. Richardson, Noel G. Morgan, Jay Young, Edward C. Burnett, Jessica L. E. Hill, Katie Partridge, Kyle C. A. Wedgwood, Mark Russell, Jessica R. Chaffey, Kaiyven A. Leslie, Pouria Akhbari, Shalinee Dhayal
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
The generation of a human pancreatic beta cell line which reproduces the responses seen in primary beta cells, but is amenable to propagation in culture, has long been an important goal in diabetes research. This is particularly true for studies focu
Autor:
Mireia Ramos-Rodríguez, Lorenzo Pasquali, Decio L. Eizirik, Knut Dahl-Jørgensen, Lars Krogvold, Helena Raurell-Vila, Jean-Valery Turatsinze, Sarah J. Richardson, Jonàs Juan-Mateu, Jessica L. E. Hill, Alexandra Coomans de Brachène, Piero Marchetti, Maikel Luis Colli, Mark Russell, Noel G. Morgan, Angela Castela, Bobbie-Jo M. Webb-Robertson, Thomas O. Metz, Lorella Marselli, Maria Inês Alvelos, Miguel Lopes, Ernesto S. Nakayasu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Nature Communications
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Nature Communications
Interferon-α (IFNα), a type I interferon, is expressed in the islets of type 1 diabetic individuals, and its expression and signaling are regulated by T1D genetic risk variants and viral infections associated with T1D. We presently characterize hum
Autor:
Jamie Bennett, Jessica L. E. Hill, Thineesha Gnaneswaran, Sarah Donegan, Brenda Strutt, David J. Hill, Sandra Szlapinski
Publikováno v:
Paediatrics Publications
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
The apelin receptor (Aplnr) and its ligands, Apelin and Apela, contribute to metabolic control. The insulin resistance associated with pregnancy is accommodated by an expansion of pancreatic β-cell mass (BCM) and increased insulin secretion, involvi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2761377e1adf9d812f1d594f077495b
https://ir.lib.uwo.ca/paedpub/2262
https://ir.lib.uwo.ca/paedpub/2262
Autor:
Renee King, Mark Russell, Brenda Strutt, David J. Hill, Noel G. Morgan, Sarah J. Richardson, Yuzhen Tong, Jessica L. E. Hill, Bibek Saha
Publikováno v:
Nutrients, Vol 11, Iss 3, p 605 (2019)
Paediatrics Publications
Nutrients
Volume 11
Issue 3
Paediatrics Publications
Nutrients
Volume 11
Issue 3
Low birth weight is a risk factor for gestational and type 2 diabetes (T2D). Since mammalian target of rapamycin (mTOR) controls pancreatic &beta
cell mass and hormone release, we hypothesized that nutritional insult in utero might permanently a
cell mass and hormone release, we hypothesized that nutritional insult in utero might permanently a
Autor:
Anne Op De Beeck, Jessica L. E. Hill, Sarah J. Richardson, Reinaldo Sousa Dos Santos, Piero Marchetti, Flavia M.M. Paula, Maikel Luis Colli, Lorella Marselli, Noel G. Morgan, Laura Marroquí, Decio L. Eizirik, Alexandra Coomans de Brachène
Publikováno v:
SSRN Electronic Journal.
Antibodies targeting PD-1 and its ligand PDL1 are used in cancer immunotherapy but may lead to autoimmune diseases, including type 1 diabetes (T1D). PD-1/PDL1 expression is probably important for maintaining tolerance, but it remains unclear whether
Autor:
Anne Op De Beeck, Sarah J. Richardson, Piero Marchetti, Lorella Marselli, Decio L. Eizirik, Pia Leete, Maikel Luis Colli, Knut Dahl-Jørgensen, Reinaldo Sousa Dos Santos, Alexandra Coomans de Brachène, Lars Krogvold, Jessica R. Chaffey, Noel G. Morgan, Flavia M.M. Paula, Angela Castela, Jessica L. E. Hill, Laura Marroquí
Publikováno v:
EBioMedicine
EBioMedicine, 36
EBioMedicine, 36
Antibodies targeting PD-1 and its ligand PDL1 are used in cancer immunotherapy but may lead to autoimmune diseases, including type 1 diabetes (T1D). It remains unclear whether PDL1 is expressed in pancreatic islets of people with T1D and how is it re