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pro vyhledávání: '"Jessica L. Danger"'
Autor:
Poulomee Sarkar, Jessica L. Danger, Ira Jain, Laura A. Meadows, Christopher Beam, Josette Medicielo, Cameron Burgess, James M. Musser, Paul Sumby
Publikováno v:
mSphere, Vol 3, Iss 5 (2018)
ABSTRACT Populations of a bacterial pathogen, whether recovered from a single patient or from a worldwide study, are often a heterogeneous mix of genetically and phenotypically divergent strains. Such heterogeneity is of value in changing environment
Externí odkaz:
https://doaj.org/article/df3136ebea0b42d1bef0975929d58596
Publikováno v:
J Bacteriol
The group A Streptococcus (GAS; Streptococcus pyogenes) causes an elaborate array of human diseases. In part, such variability in disease potential is a consequence of GAS manipulating the expression of a catalogue of virulence factors, with regulati
Publikováno v:
Infection and Immunity. 89
Serotype M28 isolates of the group A Streptococcus (GAS; Streptococcus pyogenes) are non-randomly associated with cases of puerperal sepsis, a potentially life-threatening infection that can occur in women following childbirth. Previously, we discove
Publikováno v:
Molecular Microbiology
Summary The group A Streptococcus (GAS) causes diseases that range from mild (e.g. pharyngitis) to severely invasive (e.g. necrotizing fasciitis). Strain‐ and serotype‐specific differences influence the ability of isolates to cause individual dis
Autor:
Josette Medicielo, Cameron Burgess, Ira Jain, Roshika Roshika, Paul Sumby, Jessica L. Danger, Gregory Calfee, Anupama Ramalinga, Poulomee Sarkar
Publikováno v:
J Infect Dis
BackgroundBacterial infections following childbirth—so-called puerperal infections—cause morbidity in 5%–10% of all new mothers. At low frequency, the infection can spread to the blood, resulting in life-threatening sepsis known as puerperal se
Autor:
Roshika, Roshika, Ira, Jain, Josette, Medicielo, Jasmin, Wächter, Jessica L, Danger, Paul, Sumby
Publikováno v:
Infect Immun
Serotype M28 isolates of the group A Streptococcus (GAS; Streptococcus pyogenes) are nonrandomly associated with cases of puerperal sepsis, a potentially life-threatening infection that can occur in women following childbirth. Previously, we discover
Publikováno v:
Journal of Bacteriology. 197:3720-3730
The group A Streptococcus (GAS; Streptococcus pyogenes ) causes more than 700 million human infections each year. The success of this pathogen can be traced in part to the extensive arsenal of virulence factors that are available for expression in te
Autor:
Christopher Beam, Poulomee Sarkar, Josette Medicielo, Jessica L. Danger, Ira Jain, Paul Sumby, Cameron Burgess, Laura A. Meadows, James M. Musser
Publikováno v:
mSphere, Vol 3, Iss 5 (2018)
Populations of a bacterial pathogen, whether recovered from a single patient or from a worldwide study, are often a heterogeneous mix of genetically and phenotypically divergent strains. Such heterogeneity is of value in changing environments and ari
Autor:
Brian Tjaden, Poulomee Sarkar, Ira Jain, Jessica L. Danger, Eric W. Miller, Paul Sumby, Gregory Calfee, Bernd Kreikemeyer
Publikováno v:
Infection and Immunity. 86
Isolates of a given bacterial pathogen often display phenotypic variation, and this can negatively impact public health, for example, by reducing the efficacy of preventative measures. Here, we identify that the human pathogen group A Streptococcus (
Autor:
Anupama Ramalinga, Paul Sumby, Eric W. Miller, Jessica L. Danger, Samuel A. Shelburne, Nicola Horstmann
Publikováno v:
Molecular Microbiology. 98:473-489
Phenotypic heterogeneity is commonly observed between isolates of a given pathogen. Epidemiological analyses have identified that some serotypes of the group A Streptococcus (GAS) are non-randomly associated with particular disease manifestations. He