Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Jessica L. Christenson"'
Autor:
Toru Hanamura, Jessica L. Christenson, Kathleen I. O’Neill, Emmanuel Rosas, Nicole S. Spoelstra, Michelle M. Williams, Jennifer K. Richer
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-15 (2021)
Abstract Purpose Accumulating evidence has attracted attention to the androgen receptor (AR) as a biomarker and therapeutic target in breast cancer. We hypothesized that AR activity within the tumor has clinical implications and investigated whether
Externí odkaz:
https://doaj.org/article/0371be8231394e019312e132cfe5dbce
Autor:
Michelle M. Williams, Jessica L. Christenson, Kathleen I. O’Neill, Sabrina A. Hafeez, Claire L. Ihle, Nicole S. Spoelstra, Jill E. Slansky, Jennifer K. Richer
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-13 (2021)
Abstract Many immune suppressive mechanisms utilized by triple negative breast cancer (TNBC) are regulated by oncogenic epithelial-to-mesenchymal transition (EMT). How TNBC EMT impacts innate immune cells is not fully understood. To determine how TNB
Externí odkaz:
https://doaj.org/article/60e89acc1885465fafd6cd0d4bea2bf5
Autor:
Natalia B. Fernández, Sofía M. Sosa, Justin T. Roberts, María S. Recouvreux, Luciana Rocha-Viegas, Jessica L. Christenson, Nicole S. Spoelstra, Facundo L. Couto, Ana R. Raimondi, Jennifer K. Richer, Natalia Rubinstein
Publikováno v:
Cells, Vol 12, Iss 3, p 444 (2023)
Triple negative breast cancer (TNBC) is an aggressive breast cancer subtype for which no effective targeted therapies are available. Growing evidence suggests that chemotherapy-resistant cancer cells with stem-like properties (CSC) may repopulate the
Externí odkaz:
https://doaj.org/article/82ee5a10864e493fb5f423a04c49e88e
Autor:
Michelle M. Williams, Sabrina A. Hafeez, Jessica L. Christenson, Kathleen I. O’Neill, Nia G. Hammond, Jennifer K. Richer
Publikováno v:
Pharmaceuticals, Vol 14, Iss 11, p 1122 (2021)
Approval of checkpoint inhibitors for treatment of metastatic triple negative breast cancer (mTNBC) has opened the door for the use of immunotherapies against this disease. However, not all patients with mTNBC respond to current immunotherapy approac
Externí odkaz:
https://doaj.org/article/e2edb5704120464694919c5e63ee7665
Publikováno v:
American journal of physiology. Cell physiology. 323(6)
Metastatic cancer is difficult to treat and is responsible for the majority of cancer-related deaths. After cancer cells initiate metastasis and successfully seed a distant site, resident cells in the tissue play a key role in determining how metasta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4d20cb0e33b922470f2b0737b2c2d9
https://pubmed.ncbi.nlm.nih.gov/36252127
https://pubmed.ncbi.nlm.nih.gov/36252127
Autor:
Jennifer K. Richer, Joel R. Eisner, Anthony Elias, Elaina T. Van Patten, Jordan Reese, G. Devon Trahan, Kenneth L. Jones, Nicole S. Spoelstra, Michelle M. Williams, Kathleen I. O'Neill, Jessica L. Christenson
Single-cell RNAseq of AR expressing MDA-MB-453 TNBC cells. scRNAseq was performed on untreated MDA-MB-453 cells cultured in full serum media. Cells were divided in groups based on their expression of AR, ARLow and ARHigh. (A) tSNE plot of AR levels i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bbf37a51d74bc33ff7d21665e1ab4ca
https://doi.org/10.1158/1535-7163.22522315.v1
https://doi.org/10.1158/1535-7163.22522315.v1
Autor:
Jennifer K. Richer, Jill E. Slansky, Virginia F. Borges, Kathleen Torkko, Rachel Culp-Hill, Angelo D'Alessandro, Jessica L. Christenson, Tullia C. Bruno, Lisa I. Greene
Summary of patient data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46c8a7d8338a9ea85803eb9720207c83
https://doi.org/10.1158/1541-7786.22516348
https://doi.org/10.1158/1541-7786.22516348
Autor:
Jennifer K. Richer, James R. Lambert, Diana M. Cittelly, Aik-Choon Tan, Jimin Shin, Greg D. Degala, Angelo D'Alessandro, Travis Nemkov, Michael A. Gordon, Michelle M. Williams, Kathleen I. O'Neill, Lisa I. Greene, Jessica L. Christenson, Thomas J. Rogers
Comparison of Gene Signatures following miR-200c Restoration in TNBC Cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e2e34fce6fd246f0255ad336746aaa
https://doi.org/10.1158/1541-7786.22515610.v1
https://doi.org/10.1158/1541-7786.22515610.v1
Autor:
Jennifer K. Richer, Joel R. Eisner, Anthony Elias, Elaina T. Van Patten, Jordan Reese, G. Devon Trahan, Kenneth L. Jones, Nicole S. Spoelstra, Michelle M. Williams, Kathleen I. O'Neill, Jessica L. Christenson
Gene expression changes following DHT treatment in HCI-009 PDXs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c53a70a81f9c0d97a096182a3c60a86
https://doi.org/10.1158/1535-7163.22522306.v1
https://doi.org/10.1158/1535-7163.22522306.v1
Autor:
Jennifer K. Richer, James R. Lambert, Diana M. Cittelly, Aik-Choon Tan, Jimin Shin, Greg D. Degala, Angelo D'Alessandro, Travis Nemkov, Michael A. Gordon, Michelle M. Williams, Kathleen I. O'Neill, Lisa I. Greene, Jessica L. Christenson, Thomas J. Rogers
Expanded GSEA results following miR-200c restoration in TNBC cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::555ec23b551357ccd1c7aa389b86c5fc
https://doi.org/10.1158/1541-7786.22515607.v1
https://doi.org/10.1158/1541-7786.22515607.v1