Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jessica L. Beers"'
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 3, Pp 320-332 (2023)
Abstract Cannabidiol (CBD) is approved for treatment of seizures associated with two forms of epilepsy that become apparent in infancy or early childhood. To consider an adult physiologically‐based pharmacokinetic (PBPK) model for pediatric scaling
Externí odkaz:
https://doaj.org/article/5c080e5b866245dbabe47413166f9d7b
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 484 (2024)
Cannabinoid use has surged in the past decade, with a growing interest in expanding cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC) applications into special populations. Consequently, the increased use of CBD and THC raises the risk of drug
Externí odkaz:
https://doaj.org/article/72136d7239ca4c84a3287935c146c0a6
A Review of CYP-Mediated Drug Interactions: Mechanisms and In Vitro Drug-Drug Interaction Assessment
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 99 (2024)
Drug metabolism is a major determinant of drug concentrations in the body. Drug-drug interactions (DDIs) caused by the co-administration of multiple drugs can lead to alteration in the exposure of the victim drug, raising safety or effectiveness conc
Externí odkaz:
https://doaj.org/article/5d7237d0277e4a00bb3d0ee8d46f696a
Publikováno v:
ACS Medicinal Chemistry Letters. 14:614-620
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22c933b47300cbb6f0046611a8870395
https://doi.org/10.1021/acsmedchemlett.3c00017
https://doi.org/10.1021/acsmedchemlett.3c00017
Autor:
Boris Reidel, Sabri Abdelwahab, Joe Alexander Wrennall, Phillip W. Clapp, Jessica L. Beers, Klarissa D. Jackson, Robert Tarran, Mehmet Kesimer
Publikováno v:
Journal of Applied Toxicology. 43:680-693
E-cigarette, or vaping product use-associated lung injury (EVALI), is a severe respiratory disorder that caused a sudden outbreak of hospitalized young people in 2019. Using cannabis oil containing vaping products, including vitamin E acetate contami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fca263c7842bf27e4941d7b7b86dfc21
https://doi.org/10.1002/jat.4415
https://doi.org/10.1002/jat.4415
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Toxicology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::495fff4abbdcbca85df28645ee26aba2
https://doi.org/10.1124/jpet.122.241590
https://doi.org/10.1124/jpet.122.241590
Publikováno v:
CPT: pharmacometricssystems pharmacology.
Cannabidiol (CBD) is approved for treatment of seizures associated with two forms of epilepsy that become apparent in infancy or early childhood. To consider an adult physiologically based pharmacokinetic (PBPK) model for pediatric scaling, we assess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3517d667187e264c30d5c12864c9a65
https://pubmed.ncbi.nlm.nih.gov/36540909
https://pubmed.ncbi.nlm.nih.gov/36540909
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ae73e29254b3effdb63507de0d25fc6
https://doi.org/10.1096/fasebj.2022.36.s1.r3054
https://doi.org/10.1096/fasebj.2022.36.s1.r3054
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce66574c0c7227c6857b6bbeb888ae4b
https://doi.org/10.1096/fasebj.2022.36.s1.r4072
https://doi.org/10.1096/fasebj.2022.36.s1.r4072
Autor:
Elizabeth A. Burnham, Arsany A. Abouda, Jennifer E. Bissada, Dasean T. Nardone-White, Jessica L. Beers, Jonghwa Lee, Matthew J. Vergne, Klarissa D. Jackson
Publikováno v:
Chem Res Toxicol
Sunitinib is an orally administered tyrosine kinase inhibitor associated with idiosyncratic hepatotoxicity; however, the mechanisms of this toxicity remain unclear. We have previously shown that cytochromes P450 1A2 and 3A4 catalyze sunitinib metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05d990170cfc8a11098839d72af6369
https://europepmc.org/articles/PMC9131896/
https://europepmc.org/articles/PMC9131896/
