Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jessica L. Andersen"'
Autor:
Toshinori Agatsuma, George D. Demetri, Atsushi Ochiai, Toshihiko Doi, Suzanne George, Matthew L. Hemming, Sandro Santagata, Jessica L. Andersen, Taisei Nomura, Yuki Abe, Reiko Kamei, Koichiro Inaki, Takashi Nakada, Tsuyoshi Karibe, Takuma Iguchi, Jun Hasegawa, Manabu Abe, Chiharu Hattori, Michiko Kitamura, Satoru Yasuda, Tomoko Shibutani, Akiko Kawano Nagatsuma, Amr H. Abdelhamid Ahmed, Kenji Iida
Currently, the only approved treatments for gastrointestinal stromal tumor (GIST) are tyrosine kinase inhibitors (TKI), which eventually lead to the development of secondary resistance mutations in KIT or PDGFRA and disease progression. Herein, we id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ff5c1a35e538f0f23815d732707bbe
https://doi.org/10.1158/2159-8290.c.6549451.v1
https://doi.org/10.1158/2159-8290.c.6549451.v1
Autor:
Toshinori Agatsuma, George D. Demetri, Atsushi Ochiai, Toshihiko Doi, Suzanne George, Matthew L. Hemming, Sandro Santagata, Jessica L. Andersen, Taisei Nomura, Yuki Abe, Reiko Kamei, Koichiro Inaki, Takashi Nakada, Tsuyoshi Karibe, Takuma Iguchi, Jun Hasegawa, Manabu Abe, Chiharu Hattori, Michiko Kitamura, Satoru Yasuda, Tomoko Shibutani, Akiko Kawano Nagatsuma, Amr H. Abdelhamid Ahmed, Kenji Iida
Characteristics for GIST patient samples, GPR20 expression in KIT/PDGFRA wild type GIST, GPR20 expression in normal, malignant and sarcoma tissue microarrays.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27293cf28c63fa839c7af8be6d843fa1
https://doi.org/10.1158/2159-8290.22540666
https://doi.org/10.1158/2159-8290.22540666
Autor:
Toshinori Agatsuma, George D. Demetri, Atsushi Ochiai, Toshihiko Doi, Suzanne George, Matthew L. Hemming, Sandro Santagata, Jessica L. Andersen, Taisei Nomura, Yuki Abe, Reiko Kamei, Koichiro Inaki, Takashi Nakada, Tsuyoshi Karibe, Takuma Iguchi, Jun Hasegawa, Manabu Abe, Chiharu Hattori, Michiko Kitamura, Satoru Yasuda, Tomoko Shibutani, Akiko Kawano Nagatsuma, Amr H. Abdelhamid Ahmed, Kenji Iida
S1: Expression of GPR20 in clinical GIST specimens from NCCHE S2: Representative images of GPR20 expression in various sarcoma including GIST in University of Basel derived TMA. S3: GPR20 was not expressed in systemic mastocytosis. S4: Protein expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::972e3baf460726f896fad4d66dcaea01
https://doi.org/10.1158/2159-8290.22540669
https://doi.org/10.1158/2159-8290.22540669
Autor:
Ewa Sicinska, George D. Demetri, Anthony Letai, Suzanne George, Chandrajit P. Raut, Brian D. Crompton, Morgan R. Benson, Kelly S. Klega, Jessica L. Andersen, Elizaveta Lavrova, Leona A. Doyle, Madeleine L. Taddei, Justin A. Anderson, Michael A. Loycano, Patrick Bhola, Matthew L. Hemming
Supplementary Table from Preclinical Modeling of Leiomyosarcoma Identifies Susceptibility to Transcriptional CDK Inhibitors through Antagonism of E2F-Driven Oncogenic Gene Expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d14dbb91f4e7590044f3aade67c8d08
https://doi.org/10.1158/1078-0432.22488117
https://doi.org/10.1158/1078-0432.22488117
Autor:
Sandro Santagata, George D. Demetri, Scott A. Armstrong, Peter K. Sorger, Matt van de Rijn, Amr H. Abdelhamid Ahmed, Emanuele Mazzola, Joanna Przybyl, Jessica L. Andersen, Jia-Ren Lin, Shannon Coy, Matthew L. Hemming
BARX1-/HAND1- GIST
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dfedf16754047cafda1f3b231e33d98
https://doi.org/10.1158/1078-0432.22480482
https://doi.org/10.1158/1078-0432.22480482
Autor:
Sandro Santagata, George D. Demetri, Scott A. Armstrong, Peter K. Sorger, Matt van de Rijn, Amr H. Abdelhamid Ahmed, Emanuele Mazzola, Joanna Przybyl, Jessica L. Andersen, Jia-Ren Lin, Shannon Coy, Matthew L. Hemming
GIST Immunohistochemistry Cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::243b1d8dc052ff4de9a3d991d3c39e7a
https://doi.org/10.1158/1078-0432.22480485
https://doi.org/10.1158/1078-0432.22480485
Autor:
Ewa Sicinska, George D. Demetri, Anthony Letai, Suzanne George, Chandrajit P. Raut, Brian D. Crompton, Morgan R. Benson, Kelly S. Klega, Jessica L. Andersen, Elizaveta Lavrova, Leona A. Doyle, Madeleine L. Taddei, Justin A. Anderson, Michael A. Loycano, Patrick Bhola, Matthew L. Hemming
Supplementary Figure from Preclinical Modeling of Leiomyosarcoma Identifies Susceptibility to Transcriptional CDK Inhibitors through Antagonism of E2F-Driven Oncogenic Gene Expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37300001c59cec0c8be4c3658314bb53
https://doi.org/10.1158/1078-0432.22488129
https://doi.org/10.1158/1078-0432.22488129
Autor:
James E. Bradner, George D. Demetri, Scott A. Armstrong, Ewa Sicinska, Chandrajit P. Raut, Thomas G. Scott, Otari Chipashvili, Timothy Hagan, Jessica L. Andersen, Matthew A. Lawlor, Matthew L. Hemming
Gastrointestinal stromal tumor (GIST) is a mesenchymal neoplasm characterized by activating mutations in the related receptor tyrosine kinases KIT and PDGFRA. GIST relies on expression of these unamplified receptor tyrosine kinase (RTK) genes through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892a37a37a39293056fb095a998fdb8b
https://doi.org/10.1158/0008-5472.c.6511217
https://doi.org/10.1158/0008-5472.c.6511217
Autor:
Ewa Sicinska, George D. Demetri, Anthony Letai, Suzanne George, Chandrajit P. Raut, Brian D. Crompton, Morgan R. Benson, Kelly S. Klega, Jessica L. Andersen, Elizaveta Lavrova, Leona A. Doyle, Madeleine L. Taddei, Justin A. Anderson, Michael A. Loycano, Patrick Bhola, Matthew L. Hemming
Supplementary Data from Preclinical Modeling of Leiomyosarcoma Identifies Susceptibility to Transcriptional CDK Inhibitors through Antagonism of E2F-Driven Oncogenic Gene Expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::503cfd081509776cc6a5fa7cb8f6570d
https://doi.org/10.1158/1078-0432.22488138
https://doi.org/10.1158/1078-0432.22488138
Autor:
Sandro Santagata, George D. Demetri, Scott A. Armstrong, Peter K. Sorger, Matt van de Rijn, Amr H. Abdelhamid Ahmed, Emanuele Mazzola, Joanna Przybyl, Jessica L. Andersen, Jia-Ren Lin, Shannon Coy, Matthew L. Hemming
Purpose:Gastrointestinal stromal tumor (GIST) arises from interstitial cells of Cajal (ICC) or their precursors, which are present throughout the gastrointestinal tract. Although gastric GIST is commonly indolent and small intestine GIST more aggress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e33bdad8db1f0d154aa49910e0cc65e
https://doi.org/10.1158/1078-0432.c.6530451.v1
https://doi.org/10.1158/1078-0432.c.6530451.v1