Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jessica L Swarts"'
Autor:
Jessica B Graham, Jessica L Swarts, Sarah R Leist, Alexandra Schäfer, Vineet D Menachery, Lisa E Gralinski, Sophia Jeng, Darla R Miller, Michael A Mooney, Shannon K McWeeney, Martin T Ferris, Fernando Pardo-Manuel de Villena, Mark T Heise, Ralph S Baric, Jennifer M Lund
Publikováno v:
PLoS Pathogens, Vol 17, Iss 1, p e1009287 (2021)
The COVID-19 pandemic has revealed that infection with SARS-CoV-2 can result in a wide range of clinical outcomes in humans. An incomplete understanding of immune correlates of protection represents a major barrier to the design of vaccines and thera
Externí odkaz:
https://doaj.org/article/be424a125c6f47b582b6def18907ae94
Autor:
Jessica B Graham, Jessica L Swarts, Courtney Wilkins, Sunil Thomas, Richard Green, Aimee Sekine, Kathleen M Voss, Renee C Ireton, Michael Mooney, Gabrielle Choonoo, Darla R Miller, Piper M Treuting, Fernando Pardo Manuel de Villena, Martin T Ferris, Shannon McWeeney, Michael Gale, Jennifer M Lund
Publikováno v:
PLoS Pathogens, Vol 12, Iss 11, p e1005996 (2016)
Infection with West Nile virus (WNV) leads to a range of disease outcomes, including chronic infection, though lack of a robust mouse model of chronic WNV infection has precluded identification of the immune events contributing to persistent infectio
Externí odkaz:
https://doaj.org/article/1368135a2e7e452780f93435ca1dd3a6
Autor:
Jessica B. Graham, Jessica L. Swarts, Sarah R. Leist, Alexandra Schäfer, Timothy A. Bell, Pablo Hock, Joe Farrington, Ginger D. Shaw, Martin T. Ferris, Fernando Pardo-Manuel de Villena, Ralph S. Baric, Jennifer M. Lund
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109103- (2024)
Summary: The response to infection is generally heterogeneous and diverse, with some individuals remaining asymptomatic while others present with severe disease or a diverse range of symptoms. Here, we address the role of host genetics on immune phen
Externí odkaz:
https://doaj.org/article/6feb8dbc17114d739ae8c4075c31ef37
Autor:
Tanvi Arkatkar, Veronica Davé, Irene Cruz Talavera, Jessica B. Graham, Jessica L. Swarts, Sean M. Hughes, Timothy A. Bell, Pablo Hock, Joe Farrington, Ginger D. Shaw, Anna Kirby, Michael Fialkow, Meei-Li Huang, Keith R. Jerome, Martin T. Ferris, Florian Hladik, Joshua T. Schiffer, Martin Prlic, Jennifer M. Lund
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 10 (2023)
Mucosal infections pose a significant global health burden. Antigen-specific tissue-resident T cells are critical to maintaining barrier immunity. Previous studies in the context of systemic infection suggest that memory CD8+ T cells may also provide
Externí odkaz:
https://doaj.org/article/c1f6027d12e448b38a3cfc27c143ba2e
Autor:
Kristina R. Edwards, Sophia Jeng, Richard Green, Shannon K. McWeeney, Darla R. Miller, Fernando Pardo-Manuel de Villena, Kathleen Voss, Michael Gale, Martin T. Ferris, Michael Mooney, Jessica B. Graham, Jessica L. Swarts, Jennifer M. Lund
Publikováno v:
ImmunoHorizons
The goal of a successful immune response is to clear the pathogen while sparing host tissues from damage associated with pathogen replication and active immunity. Regulatory T cells (Treg) have been implicated in maintaining this balance as they cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777f673d17f91ff9fa2e41be3329f5c7
https://pubmed.ncbi.nlm.nih.gov/33893179
https://pubmed.ncbi.nlm.nih.gov/33893179
Autor:
Sarah R. Leist, Alexandra Schäfer, Jessica L. Swarts, Sophia Jeng, Lisa E. Gralinski, Fernando Pardo-Manuel de Villena, Ralph S. Baric, Vineet D. Menachery, Martin T. Ferris, Shannon K. McWeeney, Jessica B. Graham, Michael Mooney, Jennifer M. Lund, Darla R. Miller, Mark T. Heise
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 1, p e1009287 (2021)
PLoS Pathogens, Vol 17, Iss 1, p e1009287 (2021)
The COVID-19 pandemic has revealed that infection with SARS-CoV-2 can result in a wide range of clinical outcomes in humans. An incomplete understanding of immune correlates of protection represents a major barrier to the design of vaccines and thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5b1db446b698dd147834c7bf117f4f
http://europepmc.org/articles/PMC7875398
http://europepmc.org/articles/PMC7875398
Autor:
Shannon K. McWeeney, Ralph S. Baric, Mark T. Heise, Darla R. Miller, Michael Mooney, Lisa E. Gralinski, Martin T. Ferris, Vineet D. Menachery, Sarah R. Leist, Sophia Jeng, Jennifer M. Lund, Jessica L. Swarts, Fernando Pardo-Manuel de Villena, Jessica B. Graham, Alexandra Schäfer
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
The COVID-19 pandemic has revealed that infection with SARS-CoV-2 can result in a wide range of clinical outcomes in humans, from asymptomatic or mild disease to severe disease that can require mechanical ventilation. An incomplete understanding of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c98b63d834338d4d33fa01f6a602f49
https://doi.org/10.1101/2020.09.21.306837
https://doi.org/10.1101/2020.09.21.306837
Autor:
Kathleen Voss, Jennifer M. Lund, Richard Green, Sunil Thomas, Jessica L. Swarts, Jessica B. Graham, Aimee Sekine, Michael Gale, Renee C. Ireton
Publikováno v:
The Journal of Infectious Diseases. 219:1162-1171
Background A challenge to the design of improved therapeutic agents and prevention strategies for neuroinvasive infection and associated disease is the lack of known natural immune correlates of protection. A relevant model to study such correlates i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e15cd39b3e6de8c0184959a99ff655
https://doi.org/10.1093/infdis/jiy623
https://doi.org/10.1093/infdis/jiy623
Publikováno v:
Current Protocols in Mouse Biology. 7:221-235
The use of a mouse model to study the breadth of symptoms and disease severity seen in human West Nile virus (WNV) infection can provide insight into the kinetics of the immune response and the specific pathways responsible for control of WNV infecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0862447015b1126393205d0a9e5b4c5b
https://doi.org/10.1002/cpmo.33
https://doi.org/10.1002/cpmo.33
Autor:
Michael Gale, Jennifer M. Lund, Lisa E. Gralinski, Martin T. Ferris, Shannon K. McWeeney, Sophia Jeng, Fernando Pardo-Manuel de Villena, Ralph S. Baric, Mark T. Heise, Darla R. Miller, Gabrielle Choonoo, Jessica B. Graham, Jessica L. Swarts, Alexandra Schäfer, Richard Green, Michael Mooney, Kenneth S. Plante, Clayton R. Morrison, Vineet D. Menachery, Kathleen Voss
Publikováno v:
The Journal of Infectious Diseases
Background Virus infections result in a range of clinical outcomes for the host, from asymptomatic to severe or even lethal disease. Despite global efforts to prevent and treat virus infections to limit morbidity and mortality, the continued emergenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::782260db7282e6a77c7f7cfa4fad6e9c