Výsledky vyhledávání - "Jessica L L, Robinson"

Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17

Autor: Carlos Caldas, Jessica L. L. Robinson, Jason S. Carroll, Dong Gui Hu, Dhilushi D. Wijayakumara, Peter I. Mackenzie, Wayne D. Tilley, Theresa E. Hickey, Robyn Meech, Luke A. Selth, Apichaya Chanawong, Gerard A. Tarulli, Roslin Russell

Publikováno v: Cancer Research. 76:5881-5893

Glucuronidation is an enzymatic process that terminally inactivates steroid hormones, including estrogens and androgens, thereby influencing carcinogenesis in hormone-dependent cancers. While estrogens drive breast carcinogenesis via the estrogen rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65b8a3595b1b6d32dda111400ac64e0
https://doi.org/10.1158/0008-5472.can-15-3372

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GATA2 expression and biochemical recurrence following salvage radiation therapy for relapsing prostate cancer

Autor: Jennifer L. Peterson, Alexander S. Parker, Katherine S. Tzou, Steven E. Schild, Laura A. Vallow, Thomas M. Pisansky, Kevin J. Wu, Tracy W. Hilton, Michael G. Heckman, Jessica L. L. Robinson, Steven J. Buskirk

High GATA2 expression has been associated with an increased risk of poor clinical outcomes after radical prostatectomy; however, this has not been studied in relation to risk of biochemical recurrence (BCR) after salvage radiation therapy (SRT) for r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5eba7d8722e7ce124a17d32d4668f70
https://europepmc.org/articles/PMC5594993/

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An Examination of the Association between FOXA1 Staining Level and Biochemical Recurrence following Salvage Radiation Therapy for Recurrent Prostate Cancer

Autor: Jodi Miller, Jason S. Carroll, William J. Howat, Pamela A. Kreinest, Kevin J. Wu, Jessica L. L. Robinson, Alexander S. Parker, Thomas M. Pisansky, Tracy W. Hilton, Katherine S. Tzou, Steven J. Buskirk, Jennifer L. Peterson, Michael G. Heckman, Steven E. Schild, Laura A. Vallow

Publikováno v: PLoS ONE
PLoS ONE, Vol 11, Iss 3, p e0151785 (2016)

BACKGROUND: Standardly collected clinical and pathological patient information has demonstrated only moderate ability to predict risk of biochemical recurrence (BCR) of prostate cancer in men undergoing salvage radiation therapy (SRT) for a rising PS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d87e832ea4aabfe1c201c5b184f33411
https://www.repository.cam.ac.uk/handle/1810/292188

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Minireview: The Androgen Receptor in Breast Tissues: Growth Inhibitor, Tumor Suppressor, Oncogene?

Autor: Theresa E. Hickey, Wayne D. Tilley, Jessica L. L. Robinson, Jason S. Carroll

Publikováno v: Molecular Endocrinology. 26:1252-1267

Androgen receptor (AR) signaling exerts an antiestrogenic, growth-inhibitory influence in normal breast tissue, and this role may be sustained in estrogen receptor α (ERα)-positive luminal breast cancers. Conversely, AR signaling may promote growth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ead11335123d44c619872f190860c41
https://doi.org/10.1210/me.2012-1107

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Elevated levels of FOXA1 facilitate androgen receptor chromatin binding resulting in a CRPC-like phenotype

Autor: Jessica L. L. Robinson, Wayne D. Tilley, Anne Y. Warren, Thomas L. Carroll, Theresa E. Hickey, David E. Neal, Sarah L. Vowler, Jason S. Carroll, Nikolaos Papoutsoglou, Alastair D. Lamb

Publikováno v: Oncogene

Castration-resistant prostate cancer (CRPC) continues to pose a significant clinical challenge with new generation second-line hormonal therapies affording limited improvement in disease outcome. As the androgen receptor (AR) remains a critical drive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d7202409139183eb3cccf1e6c00424
https://www.repository.cam.ac.uk/handle/1810/292241

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Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1

Autor: David E. Neal, Caryn S. Ross-Innes, Jessica L. L. Robinson, Ian G. Mills, Wayne D. Tilley, Stewart MacArthur, Jason S. Carroll

Publikováno v: The EMBO Journal

Breast cancer is a heterogeneous disease and several distinct subtypes exist based on differential gene expression patterns. Molecular apocrine tumours were recently identified as an additional subgroup, characterised as oestrogen receptor negative a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2617e139f686cad5239f3b53f24fa047
https://europepmc.org/articles/PMC3160190/

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Abstract 2922: Androgen receptor driven transcription in a subtype of estrogen receptor negative breast cancer is controlled by FoxA1

Autor: Jason S. Carroll, Wayne D. Tilley, Jessica L. L. Robinson, David E. Neal, Gordon D. Brown

Publikováno v: Cancer Research. 72:2922-2922

Breast cancer is a heterogeneous disease and several distinct subtypes exist based on differential gene expression patterns. Molecular apocrine tumors were recently identified as an additional subgroup, characterised as ERα- AR+, but with an express

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::90efde70eef32891b839732aa5727633
https://doi.org/10.1158/1538-7445.am2012-2922

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