Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jessica L Flesher"'
Autor:
Marc C Liggins, Jessica L Flesher, Sohail Jahid, Priya Vasudeva, Victoria Eby, Shunsuke Takasuga, Junko Sasaki, Takehiko Sasaki, Raymond E Boissy, Anand K Ganesan
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007290 (2018)
PIKfyve, VAC14, and FIG4 form a complex that catalyzes the production of PI(3,5)P2, a signaling lipid implicated in process ranging from lysosome maturation to neurodegeneration. While previous studies have identified VAC14 and FIG4 mutations that le
Externí odkaz:
https://doaj.org/article/6d8395e8a22e45cc82e85a7db02d0084
Autor:
Jessica Shiu, Lihua Zhang, Griffin Lentsch, Jessica L. Flesher, Suoqin Jin, Christopher Polleys, Seong Jin Jo, Craig Mizzoni, Pezhman Mobasher, Jasmine Kwan, Francisca Rius-Diaz, Bruce J. Tromberg, Irene Georgakoudi, Qing Nie, Mihaela Balu, Anand K. Ganesan
Publikováno v:
JCI Insight, Vol 7, Iss 13 (2022)
Vitiligo is an autoimmune skin disease characterized by the destruction of melanocytes by autoreactive CD8+ T cells. Melanocyte destruction in active vitiligo is mediated by CD8+ T cells, but the persistence of white patches in stable disease is poor
Externí odkaz:
https://doaj.org/article/70db2878d8444c468566494231468fe7
Autor:
Sohail Jahid, Jose A. Ortega, Linh M. Vuong, Isabella Maria Acquistapace, Stephanie J. Hachey, Jessica L. Flesher, Maria Antonietta La Serra, Nicoletta Brindani, Giuseppina La Sala, Jacopo Manigrasso, Jose M. Arencibia, Sine Mandrup Bertozzi, Maria Summa, Rosalia Bertorelli, Andrea Armirotti, Rongsheng Jin, Zheng Liu, Chi-Fen Chen, Robert Edwards, Christopher C.W. Hughes, Marco De Vivo, Anand K. Ganesan
Publikováno v:
Cell Reports, Vol 39, Iss 1, Pp 110641- (2022)
Summary: CDC42 family GTPases (RHOJ, RHOQ, CDC42) are upregulated but rarely mutated in cancer and control both the ability of tumor cells to invade surrounding tissues and the ability of endothelial cells to vascularize tumors. Here, we use computer
Externí odkaz:
https://doaj.org/article/b20a95d5a6444819bbfaaf7b0c218769
Autor:
Jessica L. Flesher, David E. Fisher
Publikováno v:
Epigenomes, Vol 5, Iss 4, p 23 (2021)
Epigenetic regulation is a crucial component of DNA maintenance and cellular identity. As our understanding of the vast array of proteins that contribute to chromatin accessibility has advanced, the role of epigenetic remodelers in disease has become
Externí odkaz:
https://doaj.org/article/3f77b4663c36427eaa96c33b6ef600af
Autor:
Kendall Martin, Jessica L. Flesher, Rui Zhao, Klemens J. Hertel, Chia-Feng Tsai, Amber N Habowski, Yongsheng Shi, Anand K. Ganesan, Marian L. Waterman, Tujin Shi, Robert Edwards, H. Steven Wiley, Jennifer M. Bates
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-17 (2020)
Communications biology, vol 3, iss 1
Communications Biology
Communications biology, vol 3, iss 1
Communications Biology
Intestinal stem cells are non-quiescent, dividing epithelial cells that rapidly differentiate into progenitor cells of the absorptive and secretory cell lineages. The kinetics of this process is rapid such that the epithelium is replaced weekly. To d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cdbddba1eaf7796f085f3b75822d464
http://link.springer.com/article/10.1038/s42003-020-01181-z
http://link.springer.com/article/10.1038/s42003-020-01181-z
Autor:
Yeon Sook Choi, Tal H. Erlich, Max von Franque, Inbal Rachmin, Jessica L. Flesher, Erik B. Schiferle, Yi Zhang, Marcello Pereira da Silva, Alva Jiang, Allison S. Dobry, Mack Su, Sharon Germana, Sebastian Lacher, Orly Freund, Ezra Feder, Jose L. Cortez, Suyeon Ryu, Tamar Babila Propp, Yedidyah Leo Samuels, Labib R. Zakka, Marjan Azin, Christin E. Burd, Norman E. Sharpless, X. Shirley Liu, Clifford Meyer, William Gerald Austen, Branko Bojovic, Curtis L. Cetrulo, Martin C. Mihm, Dave S. Hoon, Shadmehr Demehri, Elena B. Hawryluk, David E. Fisher
Publikováno v:
Cell, vol 185, iss 12
Giant congenital melanocytic nevi are NRAS-driven proliferations that may cover up to 80% of the body surface. Their most dangerous consequence is progression to melanoma. This risk often triggers preemptive extensive surgical excisions in childhood,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1282dd3563562f2e5eb8127d9a904bb9
https://pubmed.ncbi.nlm.nih.gov/35799061
https://pubmed.ncbi.nlm.nih.gov/35799061
Autor:
Jessica Shiu, Lihua Zhang, Griffin Lentsch, Jessica L Flesher, Suoqin Jin, Christopher Polleys, Seong Jin Jo, Craig Mizzoni, Pezhman Mobasher, Jasmine Kwan, Francisca Ruis-Diaz, Bruce J Tromberg, Irene Georgakoudi, Qing Nie, Mihaela Balu, Anand K Ganesan
Vitiligo is an autoimmune skin disease that is characterized by the progressive destruction of melanocytes by autoreactive CD8+ T cells. Melanocyte destruction in active vitiligo is mediated by CD8+ T cells but why white patches in stable disease per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc100e1c6482e197f2d73d3cb0d4f341
https://doi.org/10.1101/2021.12.03.470971
https://doi.org/10.1101/2021.12.03.470971
Autor:
Jessica Shiu, Lihua Zhang, Griffin Lentsch, Jessica L. Flesher, Suoqin Jin, Christopher Polleys, Seong Jin Jo, Craig Mizzoni, Pezhman Mobasher, Jasmine Kwan, Francisca Rius-Diaz, Bruce J. Tromberg, Irene Georgakoudi, Qing Nie, Mihaela Balu, Anand K. Ganesan
Publikováno v:
JCI insight. 7(13)
Vitiligo is an autoimmune skin disease characterized by the destruction of melanocytes by autoreactive CD8+ T cells. Melanocyte destruction in active vitiligo is mediated by CD8+ T cells, but the persistence of white patches in stable disease is poor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1989201039350bc1c55e289e0ac2b9b0
https://pubmed.ncbi.nlm.nih.gov/35653192
https://pubmed.ncbi.nlm.nih.gov/35653192
Autor:
Elyse K. Paterson‐Coleman, Jonathan Neumann, Eric Pearlman, Michaela E. Marshall, Grant R. MacGregor, Anand K. Ganesan, Jessica L. Flesher, Priya Vasudeva, Rolando Ruiz-Vega
Publikováno v:
Pigment Cell Melanoma Res
MITF, a gene that is mutated in familial melanoma and Waardenburg syndrome, encodes multiple isoforms expressed from alternative promoters that share common coding exons but have unique amino termini. It is not completely understood how these isoform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69d513c6b9500d4f6ec285bb5afbf4c9
https://doi.org/10.1111/pcmr.12828
https://doi.org/10.1111/pcmr.12828
Autor:
Karsten König, Christopher Polleys, Jessica L. Flesher, Irene Georgakoudi, Lihua Zhang, Mihaela Balu, Griffin Lentsch, Suoqin Jin, Pezhman Mobasher, Bruce J. Tromberg, Qing Nie, Anand K. Ganesan, Jessica Shiu, Craig Mizzoni
Publikováno v:
Photonics in Dermatology and Plastic Surgery 2021.
Vitiligo is an immune skin disorder consisting of depigmented skin patches caused by the destruction of epidermal melanocytes. Vitiligo treatment represents a clinical challenge since the re-pigmentation mechanism is not fully understood. In this pil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbe2c3fe599eb148cf7b00e6389f267b
https://doi.org/10.1117/12.2582167
https://doi.org/10.1117/12.2582167