Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jessica L, Caldwell"'
Autor:
Gopireddy R. Reddy, Lu Ren, Phung N. Thai, Jessica L. Caldwell, Manuela Zaccolo, Julie Bossuyt, Crystal M. Ripplinger, Yang K. Xiang, Madeline Nieves-Cintrón, Nipavan Chiamvimonvat, Manuel F. Navedo
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103693- (2022)
Summary: Sinoatrial node (SAN) cells are the pacemakers of the heart. This study describes a method for culturing and infection of adult mouse SAN cells with FRET-based biosensors that can be exploited to examine signaling events. SAN cells cultured
Externí odkaz:
https://doaj.org/article/a4901bdc385443a6b47fa18fb6c488d0
Autor:
Nathan C. Denham, Charles M. Pearman, Jessica L. Caldwell, George W. P. Madders, David A. Eisner, Andrew W. Trafford, Katharine M. Dibb
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Atrial fibrillation (AF) is commonly associated with heart failure. A bidirectional relationship exists between the two—AF exacerbates heart failure causing a significant increase in heart failure symptoms, admissions to hospital and cardiovascular
Externí odkaz:
https://doaj.org/article/64909765f54e44ed91259196e8f432e2
Autor:
Lu Ren, Jessica L. Caldwell, G. R. Reddy, Phung N. Thai, Manuela Zaccolo, Julie Bossuyt, Crystal M. Ripplinger, Nipavan Chiamvimonvat, Yang Kevin Xiang, Madeline Nieves-Cintrón, Manuel F. Navedo
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103693-(2022)
iScience
iScience, vol 25, iss 1
iScience
iScience, vol 25, iss 1
Summary Sinoatrial node (SAN) cells are the pacemakers of the heart. This study describes a method for culturing and infection of adult mouse SAN cells with FRET-based biosensors that can be exploited to examine signaling events. SAN cells cultured i
Autor:
David A. Eisner, Christian Pinali, Emma J. Radcliffe, Charles M. Pearman, Katharine M. Dibb, Charlotte E.R. Smith, Andrew W. Trafford, Amy E. Watkins, Margaux A. Horn, Jessica D. Clarke, Jessica L. Caldwell, Elizabeth F. Bode, Mark Eisner, Aiste Adomaviciene, Callum J. Quinn
Transverse (t)-tubules drive the rapid and synchronous Ca2+ rise in cardiac myocytes. The virtual complete loss of atrial t-tubules in heart failure (HF) decreases Ca2+ release. It is unknown if or how atrial t-tubules can be restored and if restored
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a02108dfbd18274c30eadfa093f6d108
https://doi.org/10.1101/2021.10.28.466162
https://doi.org/10.1101/2021.10.28.466162
Autor:
Michael Lawless, Jessica L. Caldwell, Emma J. Radcliffe, Charlotte E. R. Smith, George W. P. Madders, David C. Hutchings, Lori S. Woods, Stephanie J. Church, Richard D. Unwin, Graeme J. Kirkwood, Lorenz K. Becker, Charles M. Pearman, Rebecca F. Taylor, David A. Eisner, Katharine M. Dibb, Andrew. W. Trafford
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Heart failure (HF) is characterized by poor survival, a loss of catecholamine reserve and cellular structural remodeling in the form of disorganization and loss of the transverse tubule network. Indeed, survival rates for HF are worse than many commo
Autor:
Lianguo Wang, Amanda M. Guevara, Jessica L. Caldwell, I-Ju (Eric) Lee, Beth A. Habecker, Crystal M. Ripplinger
Publikováno v:
Heart Rhythm. 19:S5
Autor:
Srinu Tapa, Eric I-Ju Lee, Crystal M. Ripplinger, Lianguo Wang, Lena Ngo, Amanda Guevara, Zhen Wang, Jessica L. Caldwell
Publikováno v:
Heart Rhythm. 18:S283-S284
Publikováno v:
Eisner, D, Trafford, A, Caldwell, J & Hutchings, D 2020, ' The Control of Diastolic Calcium in the Heart : Basic Mechanisms and Functional Implications ', Circulation research, vol. 126, no. 3 . https://doi.org/10.1161/CIRCRESAHA.119.315891
Normal cardiac function requires that intracellular Ca 2+ concentration be reduced to low levels in diastole so that the ventricle can relax and refill with blood. Heart failure is often associated with impaired cardiac relaxation. Little, however, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963832597f08b62df07738b5679a0474
https://www.research.manchester.ac.uk/portal/en/publications/the-control-of-diastolic-calcium-in-the-heart(2717f3a3-4473-4767-999a-2658fbf3172c).html
https://www.research.manchester.ac.uk/portal/en/publications/the-control-of-diastolic-calcium-in-the-heart(2717f3a3-4473-4767-999a-2658fbf3172c).html
Publikováno v:
Current Opinion in Physiology. 1:153-160
Cardiac transverse (t)-tubules play a vital role in ensuring synchronous contraction. They contain L-type Ca2+ channels which closely couple with intracellular Ca2+ release channels throughout the cell to mediate a rapid and uniform Ca2+ release. The
Publikováno v:
Heart Rhythm. 18:S465