Profound degeneration of wake-promoting neurons in Alzheimer’s disease

Autor: Jun Oh, Helmut Heinsen, Jessica Kudlacek, William W. Seeley, Celica Cosme, Christine M. Walsh, Elisa de Paula França Resende, Thomas C. Neylan, Eduardo Joaquim Lopes Alho, Jackson C. Bittencourt, Rana Eser, Dulce Ovando Morales, Salvatore Spina, Bruce L. Miller, Cathrine Petersen, Lea T. Grinberg, Alexander J. Ehrenberg, Sara R. Dunlop, Panos Theofilas

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Alzheimers Dement

Introduction Sleep-wake disturbances are a common and early feature in Alzheimer's disease (AD). The impact of early tau pathology in wake-promoting neurons (WPNs) remains unclear. Methods We performed stereology in postmortem brains from AD individu

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