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pro vyhledávání: '"Jessica Kowalski"'
Autor:
Achim Lother, Lutz Hein, Jennifer S. Esser, Lisa Deng, Jessica Kowalski, Michael Huck, David Fürst, Martin Moser, Christoph Bode
Publikováno v:
Journal of Endocrinology. 240:15-26
Aldosterone is a key factor in adverse cardiovascular remodeling by acting on the mineralocorticoid receptor (MR) in different cell types. Endothelial MR activation mediates hypertrophy, inflammation and fibrosis. Cardiovascular remodeling is often a
Autor:
Achim Lother, Chiara Suennen, Lisa Deng, Christoph Bode, Duygu Koca, Lutz Hein, Jessica Kowalski, David Meral
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 78(2)
Pulmonary hypertension is characterized by progressive remodeling of the pulmonary arteries, however, this is not therapeutically targeted yet. Aldosterone and the MR (mineralocorticoid receptor) are key drivers of cardiovascular disease, and there i