Výsledky vyhledávání - "Jessica Klockow"

Data from A Novel Theranostic Strategy for MMP-14–Expressing Glioblastomas Impacts Survival

Autor: Heike E. Daldrup-Link, Robert A. Falconer, Paul M. Loadman, Jianghong Rao, Sanjiv Sam Gambhir, Edwin Chang, Samuel Cheshier, Siddharta Mitra, Frederick T. Chin, Laura Pisani, Ketan Yerneni, Jessica Klockow, Goreti Ribeiro Morais, Kai Li, Zixin Chen, Suchismita Mohanty

Glioblastoma (GBM) has a dismal prognosis. Evidence from preclinical tumor models and human trials indicates the role of GBM-initiating cells (GIC) in GBM drug resistance. Here, we propose a new treatment option with tumor enzyme-activatable, combine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6cfde44f0d5475ce85a61715b8ac14d
https://doi.org/10.1158/1535-7163.c.6539568.v1

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Figure S3 from A Novel Theranostic Strategy for MMP-14–Expressing Glioblastomas Impacts Survival

In vivo tumorigenic assay for GIC derived from pcGBM39

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3441a5004eb6b28880d2e511422ec620
https://doi.org/10.1158/1535-7163.22510302.v1

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Figure S5 from A Novel Theranostic Strategy for MMP-14–Expressing Glioblastomas Impacts Survival

Effect of CLIO-ICT on mouse body weight

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25756b5221c0ae0144844daf4136813d
https://doi.org/10.1158/1535-7163.22510293.v1

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Figure S4 from A Novel Theranostic Strategy for MMP-14–Expressing Glioblastomas Impacts Survival

Immunofluorescent confocal images for MMP-14 expression in pcGBM39 tumors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe13905e531b4b6064fcc3b17cca59c
https://doi.org/10.1158/1535-7163.22510299.v1

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Figure S2 from A Novel Theranostic Strategy for MMP-14–Expressing Glioblastomas Impacts Survival

Flowcytometric characterization of GICs in pcGBM39 and pcGBM2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a36f152368db7a4aac8815b95b7fad
https://doi.org/10.1158/1535-7163.22510305

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Figure S6 from A Novel Theranostic Strategy for MMP-14–Expressing Glioblastomas Impacts Survival

Biodistribution and toxicity data from CLIO-ICT-treated mice

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37841fcde6664619b9fea3cf7ebda967
https://doi.org/10.1158/1535-7163.22510290

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Figure S1 from A Novel Theranostic Strategy for MMP-14–Expressing Glioblastomas Impacts Survival

CLIO-ICTs induce apoptosis in GBM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8d1de70534414ea567f1854fbf4a490
https://doi.org/10.1158/1535-7163.22510308

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A Novel Theranostic Strategy for

Autor: Suchismita, Mohanty, Zixin, Chen, Kai, Li, Goreti Ribeiro, Morais, Jessica, Klockow, Ketan, Yerneni, Laura, Pisani, Frederick T, Chin, Siddharta, Mitra, Samuel, Cheshier, Edwin, Chang, Sanjiv Sam, Gambhir, Jianghong, Rao, Paul M, Loadman, Robert A, Falconer, Heike E, Daldrup-Link

Publikováno v: Molecular Imaging

This invited commentary discusses a recent article by Mohanty et al in Molecular Cancer Therapeutics about significant therapeutic efficacies of novel theranostic nanoparticles (TNPs) for the treatment of human brain cancers in mouse models. The TNPs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9a489b1de3fb322e454efe20cbe9d875
https://pubmed.ncbi.nlm.nih.gov/28929923

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