Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jessica Kho"'
Autor:
Jessica Kho, Suhyeon Kwon, Heath Ecroyd, P Chi Pham, Huixin Wang, Shelli R McAlpine, Alana Y Huang, W Alexander Donald, Joel P Rivers
Publikováno v:
ACS Med Chem Lett
[Image: see text] We report the first small molecule peptides based on the N-terminal sequence of heat shock protein 27 (Hsp27, gene HSPB1) that demonstrates chaperone-like activity. The peptide, comprising the SWDPF sequence located at Hsp27’s ami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d09a41c52f679fa3069245c265df54d1
https://doi.org/10.1021/acsmedchemlett.0c00609
https://doi.org/10.1021/acsmedchemlett.0c00609
Publikováno v:
Frontiers in Dental Medicine, Vol 5 (2024)
This narrative review aims to discuss the incorporation of novel medical concepts and tools into dental practice, with the goal of improving early diagnosis and exploring new personalized treatment options for oral pathologies, such as caries and per
Externí odkaz:
https://doaj.org/article/eec65034df1a4e28800bcc5d5339ab24
Autor:
Shelli R. McAlpine, Samantha S. Zaiter, Lok K. O. Lam, Marwa N. Rahimi, David A. Neale, Gabriel D. Moldovan, Suhyeon Kwon, Jessica Kho, Michael Leong, Gillian Thornton, Jenane Konesan, Vickie Chan, Laura K. Buckton, Michael F. Lawler, Aldwin Guo
Publikováno v:
ACS Medicinal Chemistry Letters
Herein, we describe the synthesis and structure–activity relationships of cyclic peptides designed to target heat shock protein 90 (Hsp90). Generating 19 compounds and evaluating their binding affinity reveals that increasing electrostatic interact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d95234de22b1366007e162e32f61d2
https://doi.org/10.1021/acsmedchemlett.7b00310
https://doi.org/10.1021/acsmedchemlett.7b00310
Autor:
Nicole L. Richardson, Sheena Y. Nguyen, Samantha S. Zaiter, Jessica Kho, Yen Chin Koay, Laura K. Buckton, Daniel H. Tran, Ka Wai Lee, Shelli R. McAlpine
Publikováno v:
ChemMedChem. 11(8)
Macrocycles have several advantages over small-molecule drugs when it comes to addressing specific protein-protein interactions as therapeutic targets. Herein we report the synthesis of seven new cyclic peptide molecules and their biological activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c08933b26bfd5d2deeaad12f4fd0931f
https://pubmed.ncbi.nlm.nih.gov/26805515
https://pubmed.ncbi.nlm.nih.gov/26805515
Publikováno v:
Clinical Case Reports, Vol 10, Iss 11, Pp n/a-n/a (2022)
Abstract Cushing's disease is a rare condition caused by a benign pituitary tumor underlying adrenocorticotropic hormone excess. Medical treatment is implemented when surgical resection is not curative. We present a case of Cushing's disease with rec
Externí odkaz:
https://doaj.org/article/f9671ffa5992491bbdaa7a306f8e7bc2
Autor:
Hazem I. Assi, Rasha T. Kakati, Juliett Berro, Ibrahim Saikali, Bassem Youssef, Roula Hourany, Ibrahim Alameh, Abeer Tabbarah, Jessica Khoury, Houssein Darwish, Saada Alame
Publikováno v:
Current Oncology, Vol 28, Iss 2, Pp 1274-1279 (2021)
Papillary tumors of the pineal region (PTPR) can be observed among adults with poor prognosis and high recurrence rates. Standards of therapy involve total surgical excision along with radiation therapy, with no promising prospects for primary adjuva
Externí odkaz:
https://doaj.org/article/679ccc2a367048c191245d44b124f9a9
Autor:
Hazem I. Assi, Rasha T. Kakati, Rose Mary Attieh, Jessica Khoury, Fares Sukhon, Juliett Berro, Eman Sbaity, Ziad Salem, Arafat Tfayli, Ibrahim A. Alameh, Nagi El Saghir
Publikováno v:
Breast, Vol 52, Iss , Pp 58-63 (2020)
Introduction: By the time they complete breast cancer therapy, many young patients are still of childbearing age. We aim to estimate the incidence of pregnancies in women who completed treatment and examine the percentage of patients who received fer
Externí odkaz:
https://doaj.org/article/120b79d0e8204fe8a830b7b914b80177
Autor:
Hazem I. Assi, Ibrahim A. Alameh, Jessica Khoury, Maroun Bou Zerdan, Vanessa Akiki, Maya Charafeddine, Ghida I. El Saheb, Fares Sukhon, Eman Sbaity, Serine Baydoun, Nina Shabb, Ghina Berjawi, Mohamad B. Haidar
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
PurposeThe aim of this study was to evaluate the diagnostic ability of 2-deoxy-2-[fluorine-18]fluoro-d-glucose (18F-FDG) PET/non-contrast CT compared with those of ultrasound (US)-guided fine needle aspiration (FNA) for axillary lymph node (ALN) stag
Externí odkaz:
https://doaj.org/article/8f36003f0b4441d5b2f1de58ca1a668a
Autor:
Nour Abdul Halim, Rola El Sayed, Ibrahim A. Alameh, Jessica Khoury, Clara El Nakib, Maroun Bou Zerdan, Maya Charafeddine, Fadi Farhat, Fadi El Karak, Hazem I. Assi
Publikováno v:
Cancer Treatment and Research Communications, Vol 26, Iss , Pp 100275- (2021)
Introduction: Sarcomas are uncommon malignancies. No advances have been recently achieved despite multiple efforts. Pazopanib is a safe and effective tyrosine kinase inhibitor used in managing soft tissue sarcomas (STS) after chemotherapy failure. Ho
Externí odkaz:
https://doaj.org/article/dc0f132f975147388599a31f494987f0
Autor:
Hazem I. Assi, Nour Abdul Halim, Ibrahim Alameh, Jessica Khoury, Vicky Nahra, Fares Sukhon, Maya Charafeddine, Clara El Nakib, Nour Moukalled, Maroun Bou Zerdan, Pierre Bou Khalil
Publikováno v:
Critical Care Research and Practice, Vol 2021 (2021)
Introduction. Decisions regarding whether advanced cancer patients should be admitted to the ICU are based on a complex suite of considerations, including short- and long-term prognosis, quality of life, and therapeutic options to treat cancer. We ai
Externí odkaz:
https://doaj.org/article/929e36ff5c7e4290bd051c509871785d