Výsledky vyhledávání - "Jessica K. Shaw"

Strawberry additive increases nicotine vapor sampling and systemic exposure but does not enhance Pavlovian-based nicotine reward in mice

Autor: Theresa Patten, Natalie L. Johnson, Jessica K. Shaw, Amanda M. Dossat, Allison Dreier, Bruce A. Kimball, Daniel W. Wesson, Mariella De Biasi

Nicotine is an addictive drug whose popularity has recently increased, particularly among adolescents, due to the availability of electronic nicotine devices (i.e., “vaping”) and nicotine e-liquids containing additives with rich chemosensory prop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b861339c344b0c669fdadad4df030cc5
https://doi.org/10.1101/2022.10.19.512743

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Individual differences in dopamine uptake in the dorsomedial striatum prior to cocaine exposure predict motivation for cocaine in male rats

Autor: Ole V. Mortensen, Mariella De Biasi, Shaili Aggarwal, Marion O. Scott, Jessica K. Shaw, I. Pamela Alonso, Rodrigo A. España, Bethan M. O’Connor, Stacia I. Lewandowski

Publikováno v: Neuropsychopharmacology

A major theme of addiction research has focused on the neural substrates of individual differences in the risk for addiction; however, little is known about how vulnerable populations differ from those that are relatively protected. Here, we prospect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08feb2b4522c77c17364be5cb51f535d
https://pubmed.ncbi.nlm.nih.gov/33953341

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Dissecting the neural circuitry of fear-induced appetite suppression

Autor: Jessica K. Shaw, Mariella De Biasi

Publikováno v: Neuron

The circuit mechanisms underlying fear-induced suppression of feeding are poorly understood. To help fill this gap, mice were fear conditioned, and the resulting changes in synaptic connectivity among the locus coeruleus (LC), the parabrachial nucleu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b781b90780932da5469efbe627562dcd
https://doi.org/10.1016/j.neuron.2021.02.008

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Suvorexant, an orexin/hypocretin receptor antagonist, attenuates motivational and hedonic properties of cocaine

Autor: David J. Barker, Taylor A. Gentile, Steven J. Simmons, John W. Muschamp, Jessica K. Shaw, Rodrigo A. España

Publikováno v: Addiction Biology. 23:247-255

Orexins ('hypocretins') are peptides produced by neurons of the hypothalamus that project to structures implicated in reward and emotion processing. Converging evidence demonstrates functional roles of orexin signaling in arousal, sleep/wakefulness a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e8892162315dab43da02fb66abb5666a
https://doi.org/10.1111/adb.12507

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Hypocretin/orexin knock-out mice display disrupted behavioral and dopamine responses to cocaine

Autor: Jason L. Locke, Zachary D. Brodnik, Rodrigo A. España, Sara R. Jones, Jessica K. Shaw, Mark J. Ferris

Publikováno v: Addiction Biology. 22:1695-1705

The hypocretin/orexin (HCRT) system is implicated in reward and reinforcement processes through actions on the mesolimbic dopamine (DA) system. Here we provide evidence for the relationship between HCRT and DA in vivo in anesthetized and freely movin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::58737c2b0652ef4d9468fb38f05cd3e6
https://doi.org/10.1111/adb.12432

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Hypocretin Receptor 1 Regulation of Dopamine Neurotransmission and Motivated Behavior

Autor: Jessica K. Shaw, Emily M. Black, Yanan Zhang, Rodrigo A. España

Hypocretin- (also known as orexin) containing neurons of the lateral hypothalamus project widely throughout the brain and are implicated in a range of behaviors via signaling at hypocretin receptor 1 (HCRTr1) and hypocretin receptor 2. These neurons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::82d8505aa937a3ec7e821cafe8cefeec
https://doi.org/10.1016/b978-0-12-813751-2.00005-x

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Hypocretin receptor 1 blockade produces bimodal modulation of cocaine-associated mesolimbic dopamine signaling

Autor: Zachary D. Brodnik, D A Perrey, Yanan Zhang, K A Levy, Jessica K. Shaw, Rodrigo A. España

Publikováno v: Psychopharmacology. 234(18)

Cocaine addiction is a chronic psychiatric disorder characterized by pathological motivation to obtain cocaine and behavioral and neurochemical hypersensitivity to cocaine-associated cues. These features of cocaine addiction are thought to be driven

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b70bb8765cc1223d37dbd9c902b0ec8
https://pubmed.ncbi.nlm.nih.gov/28667509

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Clozapine N-Oxide Administration Produces Behavioral Effects in Long–Evans Rats: Implications for Designing DREADD Experiments

Autor: Sandhya Krishnan Radhakrishnan, Stewart D. Clark, Jessica K. Shaw, Richard W. Browne, Duncan A. A. MacLaren, Prachi Khare, Rodrigo A. España

Publikováno v: eNeuro

Clozapine N-oxide (CNO) is a ligand for a powerful chemogenetic system that can selectively inhibit or activate neurons; the so-called Designer Receptors Exclusively Activated by Designer Drugs (DREADD) system. This system consists of synthetic G-pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c002ef7a0c07eb396fb52f99c8775e6
http://europepmc.org/articles/PMC5089539

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