Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jessica K. Harrison"'
Autor:
Chen Dong, Shuhua Fu, Rowan M. Karvas, Brian Chew, Laura A. Fischer, Xiaoyun Xing, Jessica K. Harrison, Pooja Popli, Ramakrishna Kommagani, Ting Wang, Bo Zhang, Thorold W. Theunissen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Here the authors perform a genome-wide CRISPR-Cas9 knockout screen to systematically identify and characterize essential and growth-restricting genes in human trophoblast cells. They identify TEAD1 as a key regulator that plays an important role in t
Externí odkaz:
https://doaj.org/article/bd32546a95904b3d9c16e6c741f46e37
Autor:
Adam W. Akerman, Elizabeth N. Collins, Andrew R. Peterson, Lauren B. Collins, Jessica K. Harrison, Amari DeVaughn, Jaleel M. Townsend, Rebecca L. Vanbuskirk, Jessica Riopedre‐Maqueira, Ailet Reyes, Joyce E. Oh, Charles M. Raybuck, Jeffrey A. Jones, John S. Ikonomidis
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 16 (2021)
Background Thoracic aortic aneurysms (TAAs) occur because of abnormal remodeling of aortic extracellular matrix and are accompanied by the emergence of proteolytically active myofibroblasts. The microRNA miR‐133a regulates cellular phenotypes and i
Externí odkaz:
https://doaj.org/article/bba559186768485f8fb4ea7373e8752a
Autor:
Seongmi K. Russell, Jessica K. Harrison, Benjamin S. Olson, Hyung Joo Lee, Valerie P. O’Brien, Xiaoyun Xing, Jonathan Livny, Lu Yu, Elisha D. O. Roberson, Rajdeep Bomjan, Changxu Fan, Marina Sha, Shady Estfanous, Amal O. Amer, Marco Colonna, Thaddeus S. Stappenbeck, Ting Wang, Thomas J. Hannan, Scott J. Hultgren
Publikováno v:
Nature Microbiology. 8:875-888
Previous urinary tract infections (UTIs) can predispose one to future infections; however, the underlying mechanisms affecting recurrence are poorly understood. We previously found that UTIs in mice cause differential bladder epithelial (urothelial)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4faeea41dd8a9df4355998246b870e1a
https://doi.org/10.1038/s41564-023-01346-6
https://doi.org/10.1038/s41564-023-01346-6
Autor:
Xiaoyu Zhuo, Silas Hsu, Deepak Purushotham, Prashant K Kuntala, Jessica K Harrison, Alan Y Du, Samuel Chen, Daofeng Li, Ting Wang
Publikováno v:
Genome Research. :gr.277550.122
Genome browsers have become an intuitive and critical tool to visualize and analyze genomic features and data. Conventional genome browsers display data/annotations on a single reference genome/assembly; there are also genomic alignment viewer/browse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6ac08c49675f5d683f4c6665fcb17f9
https://doi.org/10.1101/gr.277550.122
https://doi.org/10.1101/gr.277550.122
Autor:
Daofeng Li, Deepak Purushotham, Jessica K Harrison, Silas Hsu, Xiaoyu Zhuo, Changxu Fan, Shane Liu, Vincent Xu, Samuel Chen, Jason Xu, Shinyi Ouyang, Angela S Wu, Ting Wang
Publikováno v:
Nucleic acids research.
WashU Epigenome Browser (https://epigenomegateway.wustl.edu/browser/) is a web-based genomic data exploration tool that provides visualization, integration, and analysis of epigenomic datasets. The newly renovated user interface and functions have en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::684fd5b1550f0b4a7eb257628aec63bb
https://pubmed.ncbi.nlm.nih.gov/35412637
https://pubmed.ncbi.nlm.nih.gov/35412637
Publikováno v:
Nature Methods. 19:909-910
Biological functions are not only encoded by the genome’s sequence but also regulated by its three-dimensional (3D) structure. More and more studies have revealed the importance of 3D chromatin structures in development and diseases; therefore, vis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652ecc1cfb96bf7bef6c3e81c7440cc4
https://doi.org/10.1038/s41592-022-01550-y
https://doi.org/10.1038/s41592-022-01550-y
Autor:
Chen Dong, Shuhua Fu, Rowan M. Karvas, Brian Chew, Laura A. Fischer, Xiaoyun Xing, Jessica K. Harrison, Pooja Popli, Ramakrishna Kommagani, Ting Wang, Bo Zhang, Thorold W. Theunissen
Publikováno v:
Nature communications. 13(1)
The recent derivation of human trophoblast stem cells (hTSCs) provides a scalable in vitro model system of human placental development, but the molecular regulators of hTSC identity have not been systematically explored thus far. Here, we utilize a g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b7e2ccb6ec8ce04c18a8aad323752c
https://pubmed.ncbi.nlm.nih.gov/35538076
https://pubmed.ncbi.nlm.nih.gov/35538076
Autor:
Jessica Riopedre-Maqueira, Joyce E Oh, Adam W Akerman, Amari DeVaughn, Jessica K Harrison, Charles M Raybuck, Jaleel M Townsend, Elizabeth N Collins, John S. Ikonomidis, Jeffrey A. Jones, Lauren B Collins, Andrew R Peterson, Rebecca L Vanbuskirk, Ailet Reyes
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Thoracic aortic aneurysms (TAAs) occur because of abnormal remodeling of aortic extracellular matrix and are accompanied by the emergence of proteolytically active myofibroblasts. The microRNA miR‐133a regulates cellular phenotypes and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd5a0f99c92cb210dcefc419e79c9fee
https://doi.org/10.1161/jaha.120.019862
https://doi.org/10.1161/jaha.120.019862
Autor:
Adam W Akerman, Joyce E Oh, Amari DeVaughn, John S. Ikonomidis, Elizabeth N Collins, Jessica K Harrison, Jessica Riopedre, Lauren B Collins, Charles M Raybuck
Publikováno v:
Circulation Research. 125
Rationale: Thoracic aortic aneurysms (TAA) result from dysregulated remodeling of the vascular extracellular matrix, and may occur as result of altered resident cellular phenotype. MicroRNA-133a is reduced in clinical TAA specimens and plays an inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22a23a1bdde8ffe26a5b647081d075b5
https://doi.org/10.1161/res.125.suppl_1.320
https://doi.org/10.1161/res.125.suppl_1.320