Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jessica K. Chandler"'
Autor:
Patrick M. McNutt, Katie M. Hoffman, Jessica K. Chandler, Erik A. Johnson, Marian R. Nelson, Margaret R. Eisen
Publikováno v:
Neuropharmacology
The acute toxicity of organophosphorus-based compounds is primarily a result of acetylcholinesterase inhibition in the central and peripheral nervous systems. The resulting cholinergic crisis manifests as seizure, paralysis, respiratory failure and n
Autor:
James F. Irwin, Erik A. Johnson, Teresa M. Ferrara-Bowens, Michelle Guignet, Jessica K. Chandler, Kevin Laitipaya, Matthew D. Wegner, Devin D. Palmer, Lukas J. Shumway, Joseph T. McCabe, Laura B. Tucker
Publikováno v:
Neurotoxicology. 63
Soman (GD) exposure results in status epilepticus (SE) that leads to neurodegeneration, neuroinflammation, and behavioral consequences including learning and memory deficits. The neuroinflammatory response is characterized by the upregulation of the