Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jessica J. Waninger"'
Autor:
Vincent T. Ma, Alahendra A. Chamila Perera, Yilun Sun, Merna Sitto, Jessica J. Waninger, Govind Warrier, Michael D. Green, Leslie A. Fecher, Christopher D. Lao
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundStandard combination ipilimumab/nivolumab (I/N) is given as 4 induction doses for advanced stage melanoma followed by nivolumab single-agent maintenance therapy. While many patients receive less than 4 doses due to immune-related toxicities
Externí odkaz:
https://doaj.org/article/24f277d92c434e08b89fee9a38e49630
Autor:
Jessica J. Waninger, Tyler S. Beyett, Varun V. Gadkari, Ronald F. Siebenaler, Carson Kenum, Sunita Shankar, Brandon T. Ruotolo, Arul M. Chinnaiyan, John J.G. Tesmer
Publikováno v:
Biochemistry and Biophysics Reports, Vol 29, Iss , Pp 101191- (2022)
Oncogenic mutations in KRAS result in a constitutively active, GTP-bound form that in turn activates many proliferative pathways. However, because of its compact and simple architecture, directly targeting KRAS with small molecule drugs has been chal
Externí odkaz:
https://doaj.org/article/5afdc55c4e9a499fb8675d06a6b666e1
Autor:
Jessica J. Waninger, Leslie A. Fecher, Christopher Lao, Sarah Yentz, Michael D. Green, Hakan Demirci
Publikováno v:
Cancers, Vol 14, Iss 23, p 5789 (2022)
Background: There is no standardized treatment for metastatic uveal melanoma (MUM) but immune checkpoint inhibitors (ICI) are increasingly used. While ICI has transformed the survival of metastatic cutaneous melanoma, MUM patients do not equally bene
Externí odkaz:
https://doaj.org/article/4469c6a654b840e49ca1153b4da75503
Publikováno v:
Ophthalmic Plastic & Reconstructive Surgery.
Publikováno v:
Ophthalmology.
Autor:
Gaopeng Li, Jae Eun Choi, Ilona Kryczek, Yilun Sun, Peng Liao, Shasha Li, Shuang Wei, Sara Grove, Linda Vatan, Reagan Nelson, Grace Schaefer, Steven G. Allen, Kamya Sankar, Leslie A. Fecher, Mishal Mendiratta-Lala, Timothy L. Frankel, Angel Qin, Jessica J. Waninger, Alangoya Tezel, Ajjai Alva, Christopher D. Lao, Nithya Ramnath, Marcin Cieslik, Paul W. Harms, Michael D. Green, Arul M. Chinnaiyan, Weiping Zou
Publikováno v:
Cancer Cell. 41:304-322.e7
Autor:
Ronald F, Siebenaler, Seema, Chugh, Jessica J, Waninger, Vijaya L, Dommeti, Carson, Kenum, Malay, Mody, Anudeeta, Gautam, Nidhi, Patel, Alec, Chu, Pushpinder, Bawa, Jennifer, Hon, Richard D, Smith, Heather, Carlson, Xuhong, Cao, John J G, Tesmer, Sunita, Shankar, Arul M, Chinnaiyan
Publikováno v:
PNAS nexus. 1(3)
Activating mutations in RAS GTPases drive nearly 30% of all human cancers. Our prior work described an essential role for Argonaute 2 (AGO2), of the RNA-induced silencing complex, in mutant
Autor:
Qin A; 1Division of Hematology and Oncology, University of Michigan, Ann Arbor, Michigan., Zhao S; 2Center for Biostatistics., Miah A; 3Division of Medical Oncology, and., Wei L; 2Center for Biostatistics., Patel S; 4Department of Internal Medicine, The Ohio State University, Columbus, Ohio., Johns A; 4Department of Internal Medicine, The Ohio State University, Columbus, Ohio., Grogan M; 3Division of Medical Oncology, and., Bertino EM; 3Division of Medical Oncology, and., He K; 3Division of Medical Oncology, and., Shields PG; 3Division of Medical Oncology, and., Kalemkerian GP; 1Division of Hematology and Oncology, University of Michigan, Ann Arbor, Michigan., Gadgeel SM; 1Division of Hematology and Oncology, University of Michigan, Ann Arbor, Michigan.; 5Division of Hematology and Oncology, Henry Ford Cancer Center, Detroit, Michigan., Ramnath N; 1Division of Hematology and Oncology, University of Michigan, Ann Arbor, Michigan., Schneider BJ; 1Division of Hematology and Oncology, University of Michigan, Ann Arbor, Michigan., Hassan KA; 1Division of Hematology and Oncology, University of Michigan, Ann Arbor, Michigan.; 6Department of Hematology and Oncology, Cleveland Clinic, Cleveland, Ohio; and., Szerlip N; 7Department of Neurosurgery., Chopra Z; 8Department of Medical Education, and., Journey S; 8Department of Medical Education, and., Waninger J; 8Department of Medical Education, and., Spakowicz D; 2Center for Biostatistics.; 3Division of Medical Oncology, and., Carbone DP; 3Division of Medical Oncology, and., Presley CJ; 3Division of Medical Oncology, and., Otterson GA; 3Division of Medical Oncology, and., Green MD; 9Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan., Owen DH; 3Division of Medical Oncology, and.
Publikováno v:
Journal of the National Comprehensive Cancer Network : JNCCN [J Natl Compr Canc Netw] 2021 Apr 20; Vol. 19 (8), pp. 915-921. Date of Electronic Publication: 2021 Apr 20.
Autor:
Shankar S; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Tien JC; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Siebenaler RF; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Chugh S; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Dommeti VL; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Zelenka-Wang S; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Wang XM; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Apel IJ; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Waninger J; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Eyunni S; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Xu A; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Mody M; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Goodrum A; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Zhang Y; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Tesmer JJ; Department of Biological Sciences, Purdue University, West Lafayette, IN, 47907, USA., Mannan R; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Cao X; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI, 48109, USA., Vats P; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Pitchiaya S; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Ellison SJ; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Shi J; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Kumar-Sinha C; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Crawford HC; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, 48109, USA.; Internal Medicine, University of Michigan, Ann Arbor, MI, 48109, USA., Chinnaiyan AM; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, 48109, USA. arul@umich.edu.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA. arul@umich.edu.; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI, 48109, USA. arul@umich.edu.; Department of Urology, University of Michigan, Ann Arbor, MI, 48109, USA. arul@umich.edu.; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, 48109, USA. arul@umich.edu.
Publikováno v:
Nature communications [Nat Commun] 2020 Jun 04; Vol. 11 (1), pp. 2817. Date of Electronic Publication: 2020 Jun 04.
Autor:
Waldschmidt HV, Homan KT, Cruz-Rodríguez O, Cato MC, Waninger-Saroni J, Larimore KM, Cannavo A; Center for Translational Medicine, Temple University , Philadelphia, Pennsylvania 19140, United States., Song J; Center for Translational Medicine, Temple University , Philadelphia, Pennsylvania 19140, United States., Cheung JY; Center for Translational Medicine, Temple University , Philadelphia, Pennsylvania 19140, United States., Kirchhoff PD, Koch WJ; Center for Translational Medicine, Temple University , Philadelphia, Pennsylvania 19140, United States., Tesmer JJ, Larsen SD
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2016 Apr 28; Vol. 59 (8), pp. 3793-807. Date of Electronic Publication: 2016 Apr 13.