AGS3 antagonizes LGN to balance oriented cell divisions and cell fate choices in mammalian epidermis

Autor: Carlos P Descovich, Kendall J Lough, Akankshya Jena, Jessica J Wu, Jina Yom, Danielle C Spitzer, Manuela Uppalapati, Katarzyna M Kedziora, Scott E Williams

Publikováno v: eLife, Vol 12 (2023)

Oriented cell divisions balance self-renewal and differentiation in stratified epithelia such as the skin epidermis. During peak epidermal stratification, the distribution of division angles among basal keratinocyte progenitors is bimodal, with plana

Externí odkaz: https://doaj.org/article/a0bb50460c8e4723a4d8a41ba4e782f4

Biosensors to Monitor Water Quality Utilizing Insect Odorant-Binding Proteins as Detector Elements

Autor: Spiros D. Dimitratos, Allison S. Hommel, Kenneth D. Konrad, Lauren M. Simpson, Jessica J. Wu-Woods, Daniel F. Woods

Publikováno v: Biosensors, Vol 9, Iss 2, p 62 (2019)

In the developing world, the identification of clean, potable water continues to pose a pervasive challenge, and waterborne diseases due to fecal contamination of water supplies significantly threaten public health. The ability to efficiently monitor

Externí odkaz: https://doaj.org/article/58b7486b11124a8bb4256f8e3d1c549c

Disruption of the nectin-afadin complex recapitulates features of the human cleft lip/palate syndrome CLPED1

Autor: Danielle C. Spitzer, Kendall J. Lough, Jessica J. Wu, Abby J. Bergman, Kevin M. Byrd, Scott E. Williams

Publikováno v: Development

Cleft palate (CP), one of the most common congenital diseases, arises from failures in secondary palatogenesis during embryonic development. Several human genetic syndromes featuring CP and ectodermal dysplasia have been linked to mutations in genes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69f18b4c3132f416bccc629567c68b7
https://doi.org/10.1242/dev.189241

Characterizing the Craniofacial Morphological Changes in Neural Crest Cell Specific Conditional Connexin‐43 Knock‐Out Mice

Autor: Elizabeth Jewlal, Jessica J. Wu, Katherine E. Willmore

Publikováno v: The FASEB Journal. 34:1-1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9db492fb9730cdf2bd435a2bf28312ba
https://doi.org/10.1096/fasebj.2020.34.s1.05491

Enhancing Precision in Detecting Severe Immune-Related Adverse Events: Comparative Analysis of Large Language Models and International Classification of Disease Codes in Patient Records.

Autor: Sun VH; Harvard Medical School, Boston, MA.; Cardiovascular Imaging Research Center, Massachusetts General Hospital, Boston, MA., Heemelaar JC; Harvard Medical School, Boston, MA.; Cardiovascular Imaging Research Center, Massachusetts General Hospital, Boston, MA.; Leiden University Medical Center, Leiden, the Netherlands., Hadzic I; Harvard Medical School, Boston, MA.; Artificial Intelligence in Medicine (AIM) Program, Mass General Brigham, Boston, MA.; Brigham and Women's Hospital, Boston, MA.; Maastricht University, Maastricht, the Netherlands., Raghu VK; Harvard Medical School, Boston, MA.; Cardiovascular Imaging Research Center, Massachusetts General Hospital, Boston, MA., Wu CY; Division of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital, Boston, MA.; Far Eastern Memorial Hospital, New Taipei City, Taiwan., Zubiri L; Harvard Medical School, Boston, MA.; Division of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital, Boston, MA., Ghamari A; Harvard Medical School, Boston, MA.; Cardiovascular Imaging Research Center, Massachusetts General Hospital, Boston, MA., LeBoeuf NR; Harvard Medical School, Boston, MA.; Department of Dermatology, Brigham and Women's Hospital, Boston, MA.; Center for Cutaneous Oncology, Dana-Farber Cancer Institute, Boston, MA., Abu-Shawer O; Department of Internal Medicine, Cleveland Clinic, Cleveland, OH., Kehl KL; Harvard Medical School, Boston, MA.; Division of Population Sciences, Dana-Farber Cancer Institute, Boston, MA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Grover S; Harvard Medical School, Boston, MA.; Division of Gastroenterology, Hepatology, and Endoscopy, Brigham and Women's Hospital, Boston, MA., Singh P; Harvard Medical School, Boston, MA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Suero-Abreu GA; Harvard Medical School, Boston, MA.; Cardiovascular Imaging Research Center, Massachusetts General Hospital, Boston, MA.; Division of Cardiology, Massachusetts General Hospital, Boston, MA., Wu J; Harvard Medical School, Boston, MA.; Cardiovascular Imaging Research Center, Massachusetts General Hospital, Boston, MA., Falade AS; Internal Medicine Department, Massachusetts General Brigham Salem Hospital, Salem, MA., Grealish K; Division of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital, Boston, MA., Thomas MF; Division of Gastroenterology, Oregon Health and Science University, Portland, OR.; Department of Medicine, Oregon Health and Science University, Portland, OR.; Department of Cell, Developmental, and Cancer Biology, Oregon Health and Science University, Portland, OR., Hathaway N; Division of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital, Boston, MA., Medoff BD; Harvard Medical School, Boston, MA.; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA., Gilman HK; Harvard Medical School, Boston, MA.; Cardiovascular Imaging Research Center, Massachusetts General Hospital, Boston, MA., Villani AC; Harvard Medical School, Boston, MA.; Center for Immunology and Inflammatory Diseases (CIID), Massachusetts General Hospital Krantz Family Center for Cancer Research, Boston, MA.; Broad Institute of MIT and Harvard, Cambridge, MA., Ho JS; Harvard Medical School, Boston, MA.; Cardiovascular Imaging Research Center, Massachusetts General Hospital, Boston, MA., Mooradian MJ; Harvard Medical School, Boston, MA.; Division of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital, Boston, MA., Sise ME; Harvard Medical School, Boston, MA.; Division of Nephrology, Massachusetts General Hospital, Boston, MA., Zlotoff DA; Harvard Medical School, Boston, MA.; Division of Cardiology, Massachusetts General Hospital, Boston, MA., Blum SM; Harvard Medical School, Boston, MA.; Division of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital, Boston, MA.; Center for Immunology and Inflammatory Diseases (CIID), Massachusetts General Hospital Krantz Family Center for Cancer Research, Boston, MA.; Broad Institute of MIT and Harvard, Cambridge, MA., Dougan M; Harvard Medical School, Boston, MA.; Division of Gastroenterology, Massachusetts General Hospital, Boston, MA., Sullivan RJ; Harvard Medical School, Boston, MA.; Division of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital, Boston, MA., Neilan TG; Harvard Medical School, Boston, MA.; Cardiovascular Imaging Research Center, Massachusetts General Hospital, Boston, MA.; Division of Cardiology, Massachusetts General Hospital, Boston, MA., Reynolds KL; Harvard Medical School, Boston, MA.; Division of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital, Boston, MA.

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2024 Dec 10; Vol. 42 (35), pp. 4134-4144. Date of Electronic Publication: 2024 Sep 03.