Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Jessica J O'Konek"'
Autor:
Pamela T Wong, Pascale R Leroueil, Douglas M Smith, Susan Ciotti, Anna U Bielinska, Katarzyna W Janczak, Catherine H Mullen, Jeffrey V Groom, Erin M Taylor, Crystal Passmore, Paul E Makidon, Jessica J O'Konek, Andrzej Myc, Tarek Hamouda, James R Baker
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126120 (2015)
Vaccine adjuvants have been reported to induce both mucosal and systemic immunity when applied to mucosal surfaces and this dual response appears important for protection against certain pathogens. Despite the potential advantages, however, no mucosa
Externí odkaz:
https://doaj.org/article/4084c3c916ea48baa41149fcafb14c47
Autor:
Michael N. Saunders, Claudia M. Rival, Mahua Mandal, Kayla Cramton, Laila M. Rad, Katarzyna W. Janczak, Laura A. Williams, Amogh R. Angadi, Jessica J. O’Konek, Lonnie D. Shea, Loren D. Erickson
Publikováno v:
Frontiers in Allergy, Vol 5 (2024)
IgE antibodies against the mammalian oligosaccharide allergen galactose-α-1,3-galactose (αGal) can result in a severe allergic disease known as alpha-gal syndrome (AGS). This syndrome, acquired by tick bites that cause αGal sensitization, leads to
Externí odkaz:
https://doaj.org/article/bbac7c05e8a044a5add0d3cf5958ff43
Autor:
Mohammad Farazuddin, Grant Acker, Joseph Zourob, Jessica J. O’Konek, Pamela T. Wong, Susan Morris, Andrew J. Rasky, Chang H. Kim, Nicholas W. Lukacs, James R. Baker, Jr.
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110103- (2024)
Summary: Retinoic acid (RA), controls the immunoregulatory functions of many immune cells, including dendritic cells (DCs), and is important for mucosal immunity. In DCs, RA regulates the expression of pattern recognition receptors and stimulates int
Externí odkaz:
https://doaj.org/article/55aa5bd1b6a845208fb6063fbe76ebbc
Autor:
Sonia Jangra, Jeffrey J. Landers, Gabriel Laghlali, Raveen Rathnasinghe, Prajakta Warang, Seok-Chan Park, Jessica. J. O’Konek, Gagandeep Singh, Katarzyna W. Janczak, Adolfo García-Sastre, Nandini Arya, Dilara Karadag, James R. Baker, Michael Schotsaert, Pamela T. Wong
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-18 (2023)
Abstract Multiple FDA-approved SARS-CoV-2 vaccines currently provide excellent protection against severe disease. Despite this, immunity can wane relatively fast, particularly in the elderly and novel viral variants capable of evading infection- and
Externí odkaz:
https://doaj.org/article/e0f2e171cb6d49a6bff9be7e335d5f23
Publikováno v:
Frontiers in Allergy, Vol 4 (2023)
Externí odkaz:
https://doaj.org/article/752460b32da24460b85a625fcfaa7dfc
Autor:
Sonia Jangra, Jeffrey J. Landers, Raveen Rathnasinghe, Jessica J. O’Konek, Katarzyna W. Janczak, Marilia Cascalho, Andrew A. Kennedy, Andrew W. Tai, James R. Baker, Michael Schotsaert, Pamela T. Wong
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Several SARS-CoV-2 vaccines have received EUAs, but many issues remain unresolved, including duration of conferred immunity and breadth of cross-protection. Adjuvants that enhance and shape adaptive immune responses that confer broad protection again
Externí odkaz:
https://doaj.org/article/02e1fb5d10c442a983749ef606a66613
Autor:
Mohammad Farazuddin, Jeffrey J. Landers, Katarzyna W. Janczak, Hayley K. Lindsey, Fred D. Finkelman, James R. Baker, Jessica J. O’Konek
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
We have demonstrated that intranasal immunotherapy with allergens formulated in a nanoemulsion (NE) mucosal adjuvant suppresses Th2/IgE-mediated allergic responses and protects from allergen challenge in murine food allergy models. Protection conferr
Externí odkaz:
https://doaj.org/article/cd077d7e2db64de48475073d268ae5d2
Publikováno v:
Journal of Allergy and Clinical Immunology. 150:1-11
Recent events involving the global coronavirus pandemic have focused attention on vaccination strategies. Although tremendous advances have been made in subcutaneous and intramuscular vaccines during this time, one area that has lagged in implementat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dac9d55d1cc5dff294953cf9a8a6f83
https://doi.org/10.1016/j.jaci.2022.05.002
https://doi.org/10.1016/j.jaci.2022.05.002
Autor:
Mohammad Farazuddin, Rishi R. Goel, Nicholas J. Kline, Jeffrey J. Landers, Jessica J. O'Konek, James R. Baker Jr.
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Mucosal surfaces are the primary point of entry for many infectious agents and mucosal immune responses serve as the primary defense to these pathogens. In order to mount an effective mucosal immune response, it is important to induce T cell homing t
Externí odkaz:
https://doaj.org/article/6557caa4c5e54f9887e51586894400d2
Autor:
Jay A. Berzofsky, Masaki Terabe, Gurdyal S. Besra, Petr Illarionov, Zheng Xia, Liat Izhak, Satomi Takao, Shingo Kato, Jessica J. O'Konek
Purpose: Most studies characterizing antitumor properties of invariant natural killer T (iNKT) cells have used the agonist, α-galactosylceramide (α-GalCer). However, α-GalCer induces strong, long-lasting anergy of iNKT cells, which could be a majo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a56f9ba093a1afab4b248a58326cd9ff
https://doi.org/10.1158/1078-0432.c.6520448.v1
https://doi.org/10.1158/1078-0432.c.6520448.v1
