Norepinephrine Inhibits the Proliferation of Human Bone Marrow-Derived Mesenchymal Stem Cells via β2-Adrenoceptor-Mediated ERK1/2 and PKA Phosphorylation

Autor: Rainer H. Straub, Peter Angele, Susanne Grässel, Jessica Hedderich, Frank Zaucke, Andrea Meurer, Zsuzsa Jenei-Lanzl, Karima El Bagdadi

Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 11
International Journal of Molecular Sciences, Vol 21, Iss 3924, p 3924 (2020)

Bone marrow-derived mesenchymal stem cells (BMSCs) represent an alternative to chondrocytes to support cartilage regeneration in osteoarthritis (OA). The sympathetic neurotransmitter norepinephrine (NE) has been shown to inhibit their chondrogenic po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::386d28917f4c014f1917d59f5f7f91e4
http://europepmc.org/articles/PMC7312191