Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Jessica H Hartman"'
Autor:
Katherine S. Morton, Jessica H. Hartman, Nathan Heffernan, Ian T. Ryde, Isabel W. Kenny-Ganzert, Lingfeng Meng, David R. Sherwood, Joel N. Meyer
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Diets high in saturated fat and sugar, termed “Western diets,” have been associated with several negative health outcomes, including increased risk for neurodegenerative disease. Parkinson’s disease (PD) is the second most p
Externí odkaz:
https://doaj.org/article/874606a651f54ef29a0f753f990c4cef
Autor:
Kelly R. Misare, Elizabeth A. Ampolini, Hyland C. Gonzalez, Kaitlan A. Sullivan, Xin Li, Camille Miller, Bintou Sosseh, Jaclyn B. Dunne, Christina Voelkel-Johnson, Kacy L. Gordon, Jessica H. Hartman
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Polyploid cells contain more than two copies of each chromosome. Polyploidy has important roles in development, evolution, and tissue regeneration/repair, and can arise as a programmed polyploidization event or be triggered by stress. Cancer
Externí odkaz:
https://doaj.org/article/5a58c60f1ad04f77b4fbd7f303a7d381
Autor:
Kelly R. Misare, Elizabeth A. Ampolini, Hyland C. Gonzalez, Kaitlan A. Sullivan, Xin Li, Camille Miller, Bintou Sosseh, Jaclyn B. Dunne, Christina Voelkel-Johnson, Kacy L. Gordon, Jessica H. Hartman
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/60ef9e837e9d4b1485b3a0792ebdc7aa
Autor:
Zaria K. Killingsworth, Kelly R. Misare, Abigail S. Ryan, Elizabeth A. Ampolini, Tsultrim T. Mendenhall, Melinda A. Engevik, Jessica H. Hartman
Publikováno v:
Current Research in Toxicology, Vol 7, Iss , Pp 100195- (2024)
Aims: Cytochrome P450 2E1 (CYP2E1) is a mammalian monooxygenase expressed at high levels in the liver that metabolizes low molecular weight pollutants and drugs, as well as endogenous fatty acids and ketones. Although CYP2E1 has been mainly studied i
Externí odkaz:
https://doaj.org/article/286db841821c4bd5bca14ceb69fe1c11
Autor:
Zachary R. Markovich, Jessica H. Hartman, Ian T. Ryde, Kathleen A. Hershberger, Abigail S. Joyce, Patrick L. Ferguson, Joel N. Meyer
Publikováno v:
Current Research in Toxicology, Vol 3, Iss , Pp 100084- (2022)
Aims: Mitochondrial dysfunction is implicated in several diseases, including neurological disorders such as Parkinson’s disease. However, there is uncertainty about which of the many mechanisms by which mitochondrial function can be disrupted may l
Externí odkaz:
https://doaj.org/article/af65153e866440f4a28635d49c513a85
Publikováno v:
Cells, Vol 11, Iss 2, p 288 (2022)
Cytochrome P450 2E1 (CYP2E1) is pivotal in hepatotoxicity induced by alcohol abuse and different xenobiotics. In this setting, CYP2E1 generates reactive metabolites inducing oxidative stress, mitochondrial dysfunction and cell death. In addition, thi
Externí odkaz:
https://doaj.org/article/4d00432af2bb422e8054990d7a22686d
Autor:
Jessica H. Hartman, Latasha L. Smith, Kacy L. Gordon, Ricardo Laranjeiro, Monica Driscoll, David R. Sherwood, Joel N. Meyer
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Abstract Exercise and caloric restriction improve health, including reducing risk of cardiovascular disease, neurological disease, and cancer. However, molecular mechanisms underlying these protections are poorly understood, partly due to the cost an
Externí odkaz:
https://doaj.org/article/72d3f1ab341c44bab535ac51b4bbcded
Publikováno v:
Cells
Cells, Vol 11, Iss 288, p 288 (2022)
Cells, 2022, 11 (2), pp.288. ⟨10.3390/cells11020288⟩
Cells, Vol 11, Iss 288, p 288 (2022)
Cells, 2022, 11 (2), pp.288. ⟨10.3390/cells11020288⟩
International audience; Cytochrome P450 2E1 (CYP2E1) is pivotal in hepatotoxicity induced by alcohol abuse and different xenobiotics. In this setting, CYP2E1 generates reactive metabolites inducing oxidative stress, mitochondrial dysfunction and cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df62b0b73a752379894cf114c8d2e09e
https://pubmed.ncbi.nlm.nih.gov/35053404
https://pubmed.ncbi.nlm.nih.gov/35053404
Autor:
Samuel J. Widmayer, Laura E. Jameson, Stefan Taubert, Riccardo F. Romersi, Joel N. Meyer, Jessica H. Hartman, Christina M. Bergemann, Maxwell C.K. Leung, Dillon E. King, Erik C. Andersen, Katherine S. Morton
Publikováno v:
Journal of Toxicology and Environmental Health, Part B. 24:51-94
Caenorhabditis elegans has emerged as a major model in biomedical and environmental toxicology. Numerous papers on toxicology and pharmacology in C. elegans have been published, and this species has now been adopted by investigators in academic toxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7aa5a9c58421466d698287898ed56cf
https://doi.org/10.1080/10937404.2021.1884921
https://doi.org/10.1080/10937404.2021.1884921
Autor:
Justin W.C. Leung, Jessica H. Hartman, Makayla Berry, Robert L. Eoff, Lane Smith, Alyssa Richey, Julie Gunderson, Leena Maddukuri, Callie Johnson, Megan R. Reed, Amit Ketkar
Publikováno v:
Nucleic Acids Research
We previously reported that human Rev1 (hRev1) bound to a parallel-stranded G-quadruplex (G4) from the c-MYC promoter with high affinity. We have extended those results to include other G4 motifs, finding that hRev1 exhibited stronger affinity for pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c08dd83219609f6a81157da30073a87
http://europepmc.org/articles/PMC7913688
http://europepmc.org/articles/PMC7913688