Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jessica Gorrill"'
Autor:
Anne E. Kiltie, Martin Kerr, Cheryl L. Scudamore, Ester M. Hammond, Sarah J. Jevons, Michael R.L. Stratford, James Thompson, Selvakumar Anbalagan, Jacqueline Kelly, Judith Nicholson, Jessica Gorrill, Helen Scott, Jia-Ling Ruan, Blaz Groselj
Treating mice vertically head-down in the SARRP. Preliminary experiments on freshly dead mice, irradiated then immediately subjected to autopsy, demonstrated that small bowel is at a safe distance from the field edge.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::370152db82cd00a460bcf27dfb019c46
https://doi.org/10.1158/1535-7163.22505328.v1
https://doi.org/10.1158/1535-7163.22505328.v1
Autor:
Anne E. Kiltie, Martin Kerr, Cheryl L. Scudamore, Ester M. Hammond, Sarah J. Jevons, Michael R.L. Stratford, James Thompson, Selvakumar Anbalagan, Jacqueline Kelly, Judith Nicholson, Jessica Gorrill, Helen Scott, Jia-Ling Ruan, Blaz Groselj
Panobinostat levels following IP and IV administration. Six h after injection of PAN 10 mg/kg IP or IV, plasma and selected organs were removed and PAN concentrations determined using HPLC.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d7f7f5aa1dfe53b5a6642093ff1b8aa
https://doi.org/10.1158/1535-7163.22505313
https://doi.org/10.1158/1535-7163.22505313
Autor:
Anne E. Kiltie, Martin Kerr, Cheryl L. Scudamore, Ester M. Hammond, Sarah J. Jevons, Michael R.L. Stratford, James Thompson, Selvakumar Anbalagan, Jacqueline Kelly, Judith Nicholson, Jessica Gorrill, Helen Scott, Jia-Ling Ruan, Blaz Groselj
HDAC expression and cellular response to HDAC inhibition. A) qPCR of mRNA expression of HDAC 1-11 genes in normal human urothelial cells (NHU) and RT112, CAL29 and T24 bladder cancer cells. Relative gene expression was normalised to GAPDH levels (n=3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9728a8673294b76c8363f2468d867093
https://doi.org/10.1158/1535-7163.22505322.v1
https://doi.org/10.1158/1535-7163.22505322.v1
Autor:
Anne E. Kiltie, Martin Kerr, Cheryl L. Scudamore, Ester M. Hammond, Sarah J. Jevons, Michael R.L. Stratford, James Thompson, Selvakumar Anbalagan, Jacqueline Kelly, Judith Nicholson, Jessica Gorrill, Helen Scott, Jia-Ling Ruan, Blaz Groselj
List of primers and antibodies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db777f1bf392240fa8522b12c3df0eeb
https://doi.org/10.1158/1535-7163.22505316
https://doi.org/10.1158/1535-7163.22505316
Autor:
Anne E. Kiltie, Martin Kerr, Cheryl L. Scudamore, Ester M. Hammond, Sarah J. Jevons, Michael R.L. Stratford, James Thompson, Selvakumar Anbalagan, Jacqueline Kelly, Judith Nicholson, Jessica Gorrill, Helen Scott, Jia-Ling Ruan, Blaz Groselj
Days for RT112 xenografts to treble in volume and body weights and treatment of Ku80KD xenografts. A) Days for xenografts to treble in volume (PAN+IR vs IR, p=0.06). Skin overlying the xenograft developed ulceration in two mice treated with IR alone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac539cdefbe324e89a2243145485a02
https://doi.org/10.1158/1535-7163.22505331
https://doi.org/10.1158/1535-7163.22505331
Autor:
Anne E. Kiltie, Martin Kerr, Cheryl L. Scudamore, Ester M. Hammond, Sarah J. Jevons, Michael R.L. Stratford, James Thompson, Selvakumar Anbalagan, Jacqueline Kelly, Judith Nicholson, Jessica Gorrill, Helen Scott, Jia-Ling Ruan, Blaz Groselj
As the population ages, more elderly patients require radiotherapy-based treatment for their pelvic malignancies, including muscle-invasive bladder cancer, as they are unfit for major surgery. Therefore, there is an urgent need to find radiosensitizi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81936d3c4bbc6917bb40d3d57a695170
https://doi.org/10.1158/1535-7163.c.6538026.v1
https://doi.org/10.1158/1535-7163.c.6538026.v1
Autor:
Anne E. Kiltie, Martin Kerr, Cheryl L. Scudamore, Ester M. Hammond, Sarah J. Jevons, Michael R.L. Stratford, James Thompson, Selvakumar Anbalagan, Jacqueline Kelly, Judith Nicholson, Jessica Gorrill, Helen Scott, Jia-Ling Ruan, Blaz Groselj
Supplementary methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ea70883482e1396bfcb1afd96ff7ade
https://doi.org/10.1158/1535-7163.22505319
https://doi.org/10.1158/1535-7163.22505319
Autor:
Anne E. Kiltie, Martin Kerr, Cheryl L. Scudamore, Ester M. Hammond, Sarah J. Jevons, Michael R.L. Stratford, James Thompson, Selvakumar Anbalagan, Jacqueline Kelly, Judith Nicholson, Jessica Gorrill, Helen Scott, Jia-Ling Ruan, Blaz Groselj
A) Assessment of acute large bowel damage. CD1-nude mice treated with mock treatment or PAN (10 mg/kg) +/-IR. Lesions were scored semi-quantitatively using a 0-5 scale where 0 is no lesion present to 5 where the entire organ was affected by the patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c527dbbb0fced07afb1ef127c043a24
https://doi.org/10.1158/1535-7163.22505310.v1
https://doi.org/10.1158/1535-7163.22505310.v1
Autor:
Anne E. Kiltie, Martin Kerr, Cheryl L. Scudamore, Ester M. Hammond, Sarah J. Jevons, Michael R.L. Stratford, James Thompson, Selvakumar Anbalagan, Jacqueline Kelly, Judith Nicholson, Jessica Gorrill, Helen Scott, Jia-Ling Ruan, Blaz Groselj
Radiosensitising effects of panobinostat under hypoxia. A) Effect of 24-hour 25 nM PAN or DMSO on radiosensitivity of RT112 cells under 2% O2 (hypoxia) and normoxia and exposure to irradiation under the same conditions. Normoxia data taken from (14).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c8851a67332238a1f1a1488f56cc78a
https://doi.org/10.1158/1535-7163.22505325
https://doi.org/10.1158/1535-7163.22505325
Autor:
Blaz Groselj, Jessica Gorrill, Cheryl L. Scudamore, Jong-Wei Hsu, Jia-Ling Ruan, Anne E. Kiltie
Radiotherapy combined with a radiosensitiser is effective treatment in muscle-invasive bladder cancer, but can result in severe bowel toxicity. The classical crypt assay can be used to assess gut toxicity in vivo following whole abdominal radiation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcb51ed3a5564ba9e90c6e4ab829b6c1
https://ora.ox.ac.uk/objects/uuid:87068bc8-59df-49c2-b53d-066a6e9edf85
https://ora.ox.ac.uk/objects/uuid:87068bc8-59df-49c2-b53d-066a6e9edf85