Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jessica Giacomoni"'
Autor:
Jessica Giacomoni, Malin Åkerblom, Mette Habekost, Alessandro Fiorenzano, Janko Kajtez, Marcus Davidsson, Malin Parmar, Tomas Björklund
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Direct neural conversion of endogenous non-neuronal cells, such as resident glia, into therapeutic neurons has emerged as a promising strategy for brain repair, aiming to restore lost or damaged neurons. Proof-of-concept has been obtained from animal
Externí odkaz:
https://doaj.org/article/c3d7e2d6b3b847adb1d3068e5cf75a20
Autor:
Jessica Giacomoni, Mette Habekost, Efrain Cepeda-Prado, Bengt Mattsson, Daniella Rylander Ottosson, Malin Parmar, Janko Kajtez
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 102041- (2023)
Summary: Tissue clearing is commonly used for whole-brain imaging but seldom used for brain slices. Here, we present a simple protocol to slice, immunostain, and clear sections of adult rat brains for subsequent high-resolution confocal imaging. The
Externí odkaz:
https://doaj.org/article/c0dfa2b7e4f14de895dbe51742d920da
Autor:
Alessandro Fiorenzano, Edoardo Sozzi, Marcella Birtele, Janko Kajtez, Jessica Giacomoni, Fredrik Nilsson, Andreas Bruzelius, Yogita Sharma, Yu Zhang, Bengt Mattsson, Jenny Emnéus, Daniella Rylander Ottosson, Petter Storm, Malin Parmar
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
3D brain organoids have been used to investigate human brain development and pathology. Here the authors establish human ventral midbrain organoids coupled with single cell sequencing to study developing and mature dopamine neurons and use silk scaff
Externí odkaz:
https://doaj.org/article/0673168cfbbc48178fafc719524f253a
Autor:
Alessandro Fiorenzano, Edoardo Sozzi, Marcella Birtele, Janko Kajtez, Jessica Giacomoni, Fredrik Nilsson, Andreas Bruzelius, Yogita Sharma, Yu Zhang, Bengt Mattsson, Jenny Emnéus, Daniella Rylander Ottosson, Petter Storm, Malin Parmar
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/6ac80cd882654bf0a6f605aa0b6b1832
Autor:
Jessica Giacomoni, Andreas Bruzelius, Christina-Anastasia Stamouli, Daniella Rylander Ottosson
Publikováno v:
Cells, Vol 9, Iss 11, p 2451 (2020)
Glial progenitor cells are widely distributed in brain parenchyma and represent a suitable target for future therapeutic interventions that generate new neurons via in situ reprogramming. Previous studies have shown successful reprogramming of mouse
Externí odkaz:
https://doaj.org/article/1cb102046b71465ab82421fb2fc11c0a
Autor:
Daniella Rylander Ottosson, Maria Pereira, Andreas Bruzelius, Marcella Birtele, Sara Nolbrant, Devin Chandler-Militello, Steven A. Goldman, Jessica Giacomoni, Malin Parmar, Deirdre B. Hoban
Publikováno v:
Stem Cell Reports; 15(4), pp 869-882 (2020)
Nolbrant, S, Giacomoni, J, Hoban, D B, Bruzelius, A, Birtele, M, Chandler-Militello, D, Pereira, M, Ottosson, D R, Goldman, S A & Parmar, M 2020, ' Direct Reprogramming of Human Fetal-and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons ', Stem Cell Reports, vol. 15, no. 4, pp. 869-882 . https://doi.org/10.1016/j.stemcr.2020.08.013
Stem Cell Reports
Nolbrant, S, Giacomoni, J, Hoban, D B, Bruzelius, A, Birtele, M, Chandler-Militello, D, Pereira, M, Ottosson, D R, Goldman, S A & Parmar, M 2020, ' Direct Reprogramming of Human Fetal-and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons ', Stem Cell Reports, vol. 15, no. 4, pp. 869-882 . https://doi.org/10.1016/j.stemcr.2020.08.013
Stem Cell Reports
Summary Human glial progenitor cells (hGPCs) are promising cellular substrates to explore for the in situ production of new neurons for brain repair. Proof of concept for direct neuronal reprogramming of glial progenitors has been obtained in mouse m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc8c584fa78eee6c4058c1750231cce0
https://lup.lub.lu.se/record/2ec98338-79dd-4747-bbfa-7c3186ba6174
https://lup.lub.lu.se/record/2ec98338-79dd-4747-bbfa-7c3186ba6174